Results 71 to 80 of about 10,886 (208)
Regulation of fixLJ by Hfq Controls Symbiotically Important Genes in Sinorhizobium meliloti
The RNA-binding chaperone Hfq plays critical roles in the establishment and functionality of the symbiosis between Sinorhizobium meliloti and its legume hosts. A mutation in hfq reduces symbiotic efficiency resulting in a Fix− phenotype, characterized by
Mengsheng Gao +3 more
doaj +1 more source
Effect of shear stress on Pseudomonas aeruginosa isolated from the cystic fibrosis lung [PDF]
Chronic colonization of the lungs by Pseudomonas aeruginosa is one of the major causes of morbidity and mortality in cystic fibrosis (CF) patients. To gain insights into the characteristic biofilm phenotype of P. aeruginosa in the CF lungs, mimicking the
Cornelis, Pierre +7 more
core +3 more sources
We characterised nine SPFH‐domain containing proteins in Pseudomonas aeruginosa PA14 and found remarkable sequence divergence and scattered evolutionary distribution. Functional analyses showed that single or multiple deletions had no detectable impact on growth, motility, biofilm formation, stress resistance or virulence under laboratory conditions ...
Víctor Manuel García‐Maldonado +3 more
wiley +1 more source
Reduced heme levels underlie the exponential growth defect of the Shewanella oneidensis hfq mutant. [PDF]
The RNA chaperone Hfq fulfills important roles in small regulatory RNA (sRNA) function in many bacteria. Loss of Hfq in the dissimilatory metal reducing bacterium Shewanella oneidensis strain MR-1 results in slow exponential phase growth and a reduced ...
Christopher M Brennan +9 more
doaj +1 more source
Many RNA-RNA interactions depend on molecular chaperones to form and remain stable in living cells. A prime example is the RNA chaperone Hfq, which is a critical effector involved in regulatory interactions between small RNAs (sRNAs) and cognate target ...
David Lalaouna +8 more
doaj +1 more source
Several Hfq-dependent alterations in physiology of Yersinia enterocolitica O:3 are mediated by derepression of the transcriptional regulator RovM [PDF]
In bacteria, the RNA chaperone Hfq enables pairing of small regulatory RNAs with their target mRNAs and therefore is a key player of post-transcriptional regulation network. As a global regulator, Hfq is engaged in the adaptation to external environment,
Bengoechea, José A +5 more
core +1 more source
This study revealed that the transcriptional regulator EmrR in Dickeya oryzae modulates virulence by regulating hrpL expression and c‐di‐GMP levels. It affects motility, biofilm formation, cellulase production and pathogenicity. EMSA and footprinting confirmed EmrR binds directly to the promoter of its target operon.
Mingfa Lv +12 more
wiley +1 more source
Role of the Sinorhizobium meliloti Global Regulator Hfq in Gene Regulation and Symbiosis
The RNA-binding protein Hfq is a global regulator which controls diverse cellular processes in bacteria. To begin understanding the role of Hfq in the Sinorhizobium meliloti–Medicago truncatula nitrogen-fixing symbiosis, we defined free-living and ...
Mengsheng Gao +3 more
doaj +1 more source
Hfq regulates the expression of the thermostable direct hemolysin gene in
Background The hfq gene is conserved in a wide variety of bacteria and Hfq is involved in many cellular functions such as stress responses and the regulation of gene expression.
Mawatari Kazuaki +5 more
doaj +1 more source
To precisely modulate natural and synthetic regulatory parts, SUPER is introduced as a sophisticated and tunable controller of genetic devices without requiring sequence modification on the target. SUPER enhances dynamic range of RNA‐, chemical‐, temperature‐, and protein‐responsive biosensors up to 1011%, and converts biosensors to cover an expanded ...
Taeyang Heo +3 more
wiley +1 more source

