Results 51 to 60 of about 10,886 (208)

Regulation of virulence in Francisella tularensis by small non-coding RNAs [PDF]

, 2011
Using a cDNA cloning and sequencing approach we have shown that Francisella tularensis expresses homologues of several small RNAs (sRNAs) that are well-conserved among diverse bacteria.
Alain Charbit, Eric Frapy, Guillaume Postic, Iharilalao Dubail, Jonathan Livny, Karin L. Meibom, Marion Dupuis   +6 more
core   +2 more sources

Hfq C-terminal region forms a β-rich amyloid-like motif without perturbing the N-terminal Sm-like structure

Communications Biology, 2023
Hfq is a pleitropic actor that serves as stress response and virulence factor in the bacterial cell. To execute its multiple functions, Hfq assembles into symmetric torus-shaped hexamers.
Mélanie Berbon, Denis Martinez, Estelle Morvan, Axelle Grélard, Brice Kauffmann, Jehan Waeytens, Frank Wien, Véronique Arluison, Birgit Habenstein   +8 more
doaj   +1 more source

Genome-wide transcription start site profiling in biofilm-grown Burkholderia cenocepacia J2315 [PDF]

, 2015
Background: Burkholderia cenocepacia is a soil-dwelling Gram-negative Betaproteobacterium with an important role as opportunistic pathogen in humans. Infections with B.
Coenye, Tom, Deforce, Dieter, Förstner, Konrad, Sass, Andrea, Van Acker, Heleen, Van Nieuwerburgh, Filip, Vogel, Jörg   +6 more
core   +2 more sources

The Hfq chaperone helps the ribosome mature [PDF]

The EMBO Journal, 2018
Ribosome biogenesis is a complex process that is facilitated by a large number of assembly factors. In this issue, Andrade et al (2018) provide evidence that a widely conserved RNA chaperone, Hfq, acts as a ribosomal assembly factor in bacteria. Hfq is known to support regulation of stress response genes by small RNAs.
Indra Mani Sharma, Arthur Korman, Sarah A Woodson   +2 more
openaire   +2 more sources

Amyloid-like Hfq interaction with single-stranded DNA: involvement in recombination and replication in Escherichia coli

QRB Discovery, 2022
Interactions between proteins and single-stranded DNA (ssDNA) are crucial for many fundamental biological processes, including DNA replication and genetic recombination.
Krzysztof Kubiak, Frank Wien, Indresh Yadav, Nykola C. Jones, Søren Vrønning Hoffmann, Eric Le Cam, Antoine Cossa, Frederic Geinguenaud, Johan R. C. van der Maarel, Grzegorz Węgrzyn, Véronique Arluison   +10 more
doaj   +1 more source

Bacterial nitrate assimilation: gene distribution and regulation [PDF]

, 2011
In the context of the global nitrogen cycle, the importance of inorganic nitrate for the nutrition and growth of marine and freshwater autotrophic phytoplankton has long been recognized.
Andrew J. Gates, Assumpção, Caballero, Cabello, Chai, Chen, Conrado Moreno-Vivián, David J. Richardson, Flores, Forchhammer, Forchhammer, Gates, Gutierrez, Ishida, Kayumov, Koropatkin, Leigh, Li, Lin, Lledó, Llácer, M. Dolores Roldán, Moreno-Vivián, Nakano, Ogawa, Ohashi, Pawlowski, Paz-Yepes, Pino, Puerta-Fernández, Ramos, Richardson, Sanders, Shao, Shu, Shu, Stuart J. Ferguson, Swanson, Szeto, Toukdarian, Víctor M. Luque-Almagro, Weiss, Weiss, Wray, Wu   +44 more
core   +1 more source

Prediction of Hfq in actinobacteria [PDF]

, 2015
AbstractHfq is the bacterial orthologue of the eukaryotic (L)Sm family of proteins found across all domains of life and potentially an ancient protein, but it has not been found in all phyletic lines. A careful search successfully identified a distant hfq orthologue in the cyanobacteria leaving the actinobacteria as the major phylum with no known hfq ...
Bora, Nagamani, Ward, Alan C, Kim, Wonyong   +2 more
openaire   +1 more source

Biological and transcriptomic studies reveal hfq is required for swimming, biofilm formation and stress response in Xanthomonas axonpodis pv. citri

BMC Microbiology, 2019
Background Hfq is a widely conserved bacterial RNA-binding protein which generally mediates the global regulatory activities involv ed in physiological process and virulence.
Xuelu Liu, Yuping Yan, Haodi Wu, Changyong Zhou, Xuefeng Wang   +4 more
doaj   +1 more source

Central role for RNase YbeY in Hfq-dependent and Hfq-independent small-RNA regulation in bacteria [PDF]

BMC Genomics, 2014
Conceptual parallels exist between bacterial and eukaryotic small-RNA (sRNA) pathways, yet relatively little is known about which protein may recognize and recruit bacterial sRNAs to interact with targets. In eukaryotes, Argonaute (AGO) proteins discharge such functions.
Pandey, Shree P., Winkler, Jonathan A., Li, Hu, Camacho, Diogo M., Collins, James J., Walker, Graham C.   +5 more
openaire   +4 more sources

Structural and biochemical studies on ATP binding and hydrolysis by the Escherichia coli RNA chaperone Hfq. [PDF]

PLoS ONE, 2012
In Escherichia coli the RNA chaperone Hfq is involved in riboregulation by assisting base-pairing between small regulatory RNAs (sRNAs) and mRNA targets. Several structural and biochemical studies revealed RNA binding sites on either surface of the donut
Hermann Hämmerle, Mads Beich-Frandsen, Branislav Večerek, Lukas Rajkowitsch, Oliviero Carugo, Kristina Djinović-Carugo, Udo Bläsi   +6 more
doaj   +1 more source