Results 31 to 40 of about 6,261 (210)
Profound impact of Hfq on nutrient acquisition, metabolism and motility in the plant pathogen Agrobacterium tumefaciens. [PDF]
PLoS ONE, 2014 As matchmaker between mRNA and sRNA interactions, the RNA chaperone Hfq plays a key role in riboregulation of many bacteria. Often, the global influence of Hfq on the transcriptome is reflected by substantially altered proteomes and pleiotropic ...
Philip Möller +6 more
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RNA Biology, 2013 The bacterial Hfq protein is a versatile modulator of RNA function and is particularly important for regulation mediated by small non-coding RNAs. Hfq is a bacterial Sm protein but bears more similarity to the eukaryotic Sm-like (Lsm) family of proteins than the prototypical Sm proteins.
Wilusz, Carol J., Wilusz, Jeffrey
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Microorganisms, 2021 Yersinia ruckeri causes outbreaks of enteric redmouth disease in salmon aquaculture all over the world. The transient antibiotic tolerance exhibited by bacterial persisters is commonly thought to be responsible for outbreaks; however, the molecular ...
Iván L. Calderón +5 more
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Overexpression of an outer membrane protein associated with decreased susceptibility to carbapenems in Proteus mirabilis. [PDF]
PLoS ONE, 2015 Proteus mirabilis isolates commonly have decreased susceptibility to imipenem. Previously, we found P. mirabilis hfq mutant was more resistant to imipenem and an outer membrane protein (OMP) could be involved.
Yi-Lin Tsai +6 more
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Involvement of the post-transcriptional regulator Hfq in Yersinia pestis virulence. [PDF]
PLoS ONE, 2009 BACKGROUND:Yersinia pestis is the causative agent of plague, which is transmitted primarily between fleas and mammals and is spread to humans through the bite of an infected flea or contact with afflicted animals.
Jing Geng +13 more
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Hfq binding changes the structure of Escherichia coli small noncoding RNAs OxyS and RprA, which are involved in the riboregulation of rpoS [PDF]
, 2013 : OxyS and RprA are two small noncoding RNAs (sRNAs) that modulate the expression of rpoS, encoding an alternative sigma factor that activates transcription of multiple Escherichia coli stress-response genes.
Taylor, James E. +28 more
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The Hfq chaperone helps the ribosome mature [PDF]
The EMBO Journal, 2018 Ribosome biogenesis is a complex process that is facilitated by a large number of assembly factors. In this issue, Andrade et al (2018) provide evidence that a widely conserved RNA chaperone, Hfq, acts as a ribosomal assembly factor in bacteria. Hfq is known to support regulation of stress response genes by small RNAs.
Indra Mani Sharma +2 more
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Hfq Globally Binds and Destabilizes sRNAs and mRNAs in
mSystems, 2019 Hfq is a ubiquitous Sm-like RNA-binding protein in bacteria involved in physiological fitness and pathogenesis, while its in vivo binding nature remains elusive. Here we reported genome-wide Hfq-bound RNAs in Yersinia pestis, a causative agent of plague,
Yanping Han +7 more
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mBio, 2017 Legionella pneumophila is an environmental bacterium that parasitizes protozoa, but it may also infect humans, thereby causing a severe pneumonia called Legionnaires’ disease. To cycle between the environment and a eukaryotic host, L.
Giulia Oliva +4 more
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Impact of Hfq on global gene expression and intracellular survival in Brucella melitensis. [PDF]
PLoS ONE, 2013 Brucella melitensis is a facultative intracellular bacterium that replicates within macrophages. The ability of brucellae to survive and multiply in the hostile environment of host macrophages is essential to its virulence. The RNA-binding protein Hfq is
Mingquan Cui +17 more
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