Results 21 to 30 of about 6,780 (207)

Bacillus subtilis Hfq: A role in chemotaxis and motility

Journal of Biosciences, 2016
Hfq is a global post-transcriptional regulator that modulates the translation and stability of target mRNAs and thereby regulates pleiotropic functions, such as growth, stress, virulence and motility, in many Gram-negative bacteria.
KUMAR, P, RAO, KK, JAGTAP, CB
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RNA reflections: converging on Hfq [PDF]

RNA, 2015
As the journal RNA celebrates its 20th anniversary, the role of non-coding RNAs as regulators is firmly established in a broad range of organisms. Among these are the many bacterial RNAs that pair with their targets and regulate mRNA stability and translation. In Escherichia coli and other gram-negative organisms, these small RNAs (sRNAs) depend on Hfq,
Gottesman, Susan, Storz, Gisela
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Hfq: the flexible RNA matchmaker [PDF]

Current Opinion in Microbiology, 2016
The RNA chaperone protein Hfq is critical to the function of small, base pairing RNAs in many bacteria. In the past few years, structures and modeling of wild type Hfq and assays of various mutants have documented that the homohexameric Hfq ring can contact RNA at four sites (proximal face, distal face, rim and C-terminal tail) and that different RNAs ...
Taylor B Updegrove, Aixia Zhang, Gisela Storz   +2 more
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Lsm proteins and Hfq [PDF]

RNA Biology, 2013
The bacterial Hfq protein is a versatile modulator of RNA function and is particularly important for regulation mediated by small non-coding RNAs. Hfq is a bacterial Sm protein but bears more similarity to the eukaryotic Sm-like (Lsm) family of proteins than the prototypical Sm proteins.
Wilusz, Carol J., Wilusz, Jeffrey
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The RNA Chaperone Hfq Participates in Persistence to Multiple Antibiotics in the Fish Pathogen Yersinia ruckeri

Microorganisms, 2021
Yersinia ruckeri causes outbreaks of enteric redmouth disease in salmon aquaculture all over the world. The transient antibiotic tolerance exhibited by bacterial persisters is commonly thought to be responsible for outbreaks; however, the molecular ...
Iván L. Calderón, María José Barros, Fernanda Montt, Fernando Gil, Juan A. Fuentes, Lillian G. Acuña   +5 more
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Overexpression of an outer membrane protein associated with decreased susceptibility to carbapenems in Proteus mirabilis. [PDF]

PLoS ONE, 2015
Proteus mirabilis isolates commonly have decreased susceptibility to imipenem. Previously, we found P. mirabilis hfq mutant was more resistant to imipenem and an outer membrane protein (OMP) could be involved.
Yi-Lin Tsai, Min-Cheng Wang, Po-Ren Hsueh, Ming-Che Liu, Rouh-Mei Hu, Yue-Jin Wu, Shwu-Jen Liaw   +6 more
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Involvement of the post-transcriptional regulator Hfq in Yersinia pestis virulence. [PDF]

PLoS ONE, 2009
BACKGROUND:Yersinia pestis is the causative agent of plague, which is transmitted primarily between fleas and mammals and is spread to humans through the bite of an infected flea or contact with afflicted animals.
Jing Geng, Yajun Song, Lei Yang, Yanyan Feng, Yefeng Qiu, Gang Li, Jingyu Guo, Yujing Bi, Yi Qu, Wang Wang, Xiaoyi Wang, Zhaobiao Guo, Ruifu Yang, Yanping Han   +13 more
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Hfq binding changes the structure of Escherichia coli small noncoding RNAs OxyS and RprA, which are involved in the riboregulation of rpoS [PDF]

, 2013
: OxyS and RprA are two small noncoding RNAs (sRNAs) that modulate the expression of rpoS, encoding an alternative sigma factor that activates transcription of multiple Escherichia coli stress-response genes.
Taylor, James E., Callaghan, Anastasia J., Helen A. Vincent, Phillips, Jack O., Cary, Peter, Vincent, H., Peter D. Cary, Sobott, F., Jack O. Phillips, Frank Sobott, Vincent, Helen A., Henderson, Charlotte A., Stone, Carlanne, Alessandra Casamento, Henderson, Charlotte, Carlanne M. Stone, Anastasia J. Callaghan, Darren M. Gowers, Cary, Peter D., Charlotte A. Henderson, James E.N. Taylor, Casamento, A., Callaghan, Anastasia, Phillips, Jack, Gowers, Darren, Casamento, Alessandra, Stone, Carlanne M., Sobott, Frank, Gowers, Darren M.   +28 more
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The Hfq chaperone helps the ribosome mature [PDF]

The EMBO Journal, 2018
Ribosome biogenesis is a complex process that is facilitated by a large number of assembly factors. In this issue, Andrade et al (2018) provide evidence that a widely conserved RNA chaperone, Hfq, acts as a ribosomal assembly factor in bacteria. Hfq is known to support regulation of stress response genes by small RNAs.
Indra Mani Sharma, Arthur Korman, Sarah A Woodson   +2 more
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Structural insights into the dynamics and function of the C-terminus of the E. coli RNA chaperone Hfq [PDF]

, 2011
The hexameric Escherichia coli RNA chaperone Hfq (Hfq(Ec)) is involved in riboregulation of target mRNAs by small trans-encoded RNAs. Hfq proteins of different bacteria comprise an evolutionarily conserved core, whereas the C-terminus is variable in ...
Beich-Frandsen, Mads (Department of Structural and Computational Biology, Centre for Molecular Biology, University of Vienna), Kontaxis, Georg (Department of Structural and Computational Biology, Centre for Molecular Biology, University of Vienna), Blasi, U., Rajkowitsch, L., Miles, Andrew (Birkbeck College), Sjöblom, Björn (Department of Structural and Computational Biology, Centre for Molecular Biology, University of Vienna), Miles, Andrew J., Svergun, D.I., Kloiber, K., Kristina Djinović-Carugo, Vecerek, B., Karin Kloiber, Konarev, P.V., Lukas Rajkowitsch, Hämmerle, Hermann Konrad (Department of Biochemistry and Cell Biology, Centre for Molecular Biology, University of Vienna), Georg Kontaxis, Bläsi, Udo (Department of Microbiology, Immunobiology and Genetics, Centre for Molecular Biology, University of Vienna), Djinovic-Carugo, K., Robert Konrat, Branislav Večerek, Konarev, Peter V. (EMBL Hamburg), Andrew J. Miles, Kloiber, Karin (Department of Structural and Computational Biology, Centre for Molecular Biology, University of Vienna), Rajkowitsch, Lukas (Department of Biochemistry and Cell Biology, Centre for Molecular Biology, University of Vienna), Udo Bläsi, Wallace, Bonnie A., Svergun, D. I., Petr V. Konarev, Svergun, Dimitri I. (EMBL Hamburg), Björn Sjöblom, Hammerle, H., Mads Beich-Frandsen, Wallace, B. A., Sjoblom, B., Miles, A. J., Konrat, Robert (Department of Structural and Computational Biology, Centre for Molecular Biology, University of Vienna), Vecerek, Branislav (Department of Microbiology, Immunobiology and Genetics, Centre for Molecular Biology, University of Vienna), Dimitri I. Svergun, B. A. Wallace, Beich Frandsen, M., Djinovic Carugo, K., Konarev, P. V., Beich-Frandsen, M., Konrat, R., Djinovic-Carugo, Kristina (Department of Structural and Computational Biology, Centre for Molecular Biology, University of Vienna), Hermann Hämmerle, Kontaxis, G.   +46 more
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