Results 11 to 20 of about 10,886 (208)
Association of RNAs with Bacillus subtilis Hfq. [PDF]
PLoS ONE, 2013 The prevalence and characteristics of small regulatory RNAs (sRNAs) have not been well characterized for Bacillus subtilis, an important model system for Gram-positive bacteria. However, B.
Michael Dambach +2 more
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Tracking the Elusive Function of Bacillus subtilis Hfq.
PLoS ONE, 2015 RNA-binding protein Hfq is a key component of the adaptive responses of many proteobacterial species including Escherichia coli, Salmonella enterica and Vibrio cholera.
Tatiana Rochat +6 more
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RNA binding of Hfq monomers promotes RelA-mediated hexamerization in a limiting Hfq environment [PDF]
Nature Communications, 2021 RelA stimulates RyhB small RNA–target mRNA interaction by promoting assembly of Hfq monomers into hexamers. Here the authors show that RelA-mediated Hfq hexamerization requires an initial binding of RNA to Hfq monomers.
Pallabi Basu +5 more
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Staphylococcus aureus pigmentation is not controlled by Hfq [PDF]
BMC Research Notes, 2020 Objective The golden color of Staphylococcus aureus is due to the synthesis of carotenoid pigments. In Gram-negative bacteria, Hfq is a global posttranscriptional regulator, but its function in S. aureus remains obscure. The absence of Hfq in S.
Wenfeng Liu +3 more
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Impact of Hfq on the Bacillus subtilis transcriptome. [PDF]
PLoS ONE, 2014 The RNA chaperone Hfq acts as a central player in post-transcriptional gene regulation in several Gram-negative Bacteria, whereas comparatively little is known about its role in Gram-positive Bacteria.
Hermann Hämmerle +5 more
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Hfq: the flexible RNA matchmaker [PDF]
Current Opinion in Microbiology, 2016 The RNA chaperone protein Hfq is critical to the function of small, base pairing RNAs in many bacteria. In the past few years, structures and modeling of wild type Hfq and assays of various mutants have documented that the homohexameric Hfq ring can contact RNA at four sites (proximal face, distal face, rim and C-terminal tail) and that different RNAs ...
Taylor B Updegrove +2 more
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RNA reflections: converging on Hfq [PDF]
RNA, 2015 As the journal RNA celebrates its 20th anniversary, the role of non-coding RNAs as regulators is firmly established in a broad range of organisms. Among these are the many bacterial RNAs that pair with their targets and regulate mRNA stability and translation. In Escherichia coli and other gram-negative organisms, these small RNAs (sRNAs) depend on Hfq,
Gottesman, Susan, Storz, Gisela
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Clostridium difficile Hfq can replace Escherichia coli Hfq for most of its function [PDF]
RNA, 2014 A gene for the Hfq protein is present in the majority of sequenced bacterial genomes. Its characteristic hexameric ring-like core structure is formed by the highly conserved N-terminal regions. In contrast, the C-terminal forms an extension, which varies in length, lacks homology, and is predicted to be unstructured.
J., Caillet +3 more
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Microorganisms, 2021 Yersinia ruckeri causes outbreaks of enteric redmouth disease in salmon aquaculture all over the world. The transient antibiotic tolerance exhibited by bacterial persisters is commonly thought to be responsible for outbreaks; however, the molecular ...
Iván L. Calderón +5 more
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Apomorphine Targets the Pleiotropic Bacterial Regulator Hfq [PDF]
Antibiotics, 2021 Hfq is a bacterial regulator with key roles in gene expression. The protein notably regulates translation efficiency and RNA decay in Gram-negative bacteria, thanks to its binding to small regulatory noncoding RNAs. This property is of primary importance for bacterial adaptation and survival in hosts.
Florian Turbant +6 more
openaire +3 more sources