Results 11 to 20 of about 6,621 (215)

Pervasive Targeting of Nascent Transcripts by Hfq

open access: yesCell Reports, 2018
Summary: Hfq is an RNA chaperone and an important post-transcriptional regulator in bacteria. Using chromatin immunoprecipitation coupled with high-throughput DNA sequencing (ChIP-seq), we show that Hfq associates with hundreds of different regions of ...
Simon Dove, Kathryn Ramsey
exaly   +7 more sources

Staphylococcus aureus pigmentation is not controlled by Hfq [PDF]

open access: yesBMC Research Notes, 2020
Objective The golden color of Staphylococcus aureus is due to the synthesis of carotenoid pigments. In Gram-negative bacteria, Hfq is a global posttranscriptional regulator, but its function in S. aureus remains obscure. The absence of Hfq in S.
Wenfeng Liu   +3 more
doaj   +4 more sources

Association of RNAs with Bacillus subtilis Hfq. [PDF]

open access: yesPLoS ONE, 2013
The prevalence and characteristics of small regulatory RNAs (sRNAs) have not been well characterized for Bacillus subtilis, an important model system for Gram-positive bacteria. However, B.
Michael Dambach   +2 more
doaj   +4 more sources

RNA binding of Hfq monomers promotes RelA-mediated hexamerization in a limiting Hfq environment [PDF]

open access: yesNature Communications, 2021
RelA stimulates RyhB small RNA–target mRNA interaction by promoting assembly of Hfq monomers into hexamers. Here the authors show that RelA-mediated Hfq hexamerization requires an initial binding of RNA to Hfq monomers.
Pallabi Basu   +5 more
doaj   +4 more sources

Impact of Hfq on the Bacillus subtilis transcriptome. [PDF]

open access: yesPLoS ONE, 2014
The RNA chaperone Hfq acts as a central player in post-transcriptional gene regulation in several Gram-negative Bacteria, whereas comparatively little is known about its role in Gram-positive Bacteria.
Hermann Hämmerle   +5 more
doaj   +6 more sources

Tracking the Elusive Function of Bacillus subtilis Hfq.

open access: yesPLoS ONE, 2015
RNA-binding protein Hfq is a key component of the adaptive responses of many proteobacterial species including Escherichia coli, Salmonella enterica and Vibrio cholera.
Tatiana Rochat   +6 more
doaj   +7 more sources

Pleiotropic regulatory function of the RNA chaperone Hfq in the Pseudomonas protegens FD6

open access: yesPhytopathology Research
The rhizosphere bacterium Pseudomonas protegens FD6, which is associated with the production of antibiotics such as pyoluteorin (PLT) and 2,4-diacetylphloroglucinol (2,4-DAPG), has strong antagonistic effects on phytopathogens.
Deyu Wen   +7 more
doaj   +2 more sources

Amyloid-like Hfq interaction with single-stranded DNA: involvement in recombination and replication in Escherichia coli

open access: yesQRB Discovery, 2022
Interactions between proteins and single-stranded DNA (ssDNA) are crucial for many fundamental biological processes, including DNA replication and genetic recombination.
Krzysztof Kubiak   +10 more
doaj   +2 more sources

The RNA chaperone Hfq is involved in stress tolerance and virulence in uropathogenic Proteus mirabilis. [PDF]

open access: yesPLoS ONE, 2014
Hfq is a bacterial RNA chaperone involved in the riboregulation of diverse genes via small noncoding RNAs. Here, we show that Hfq is critical for the uropathogenic Proteus mirabilis to effectively colonize the bladder and kidneys in a murine urinary ...
Min-Cheng Wang   +4 more
doaj   +1 more source

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