Results 41 to 50 of about 6,261 (210)
RNA Biology, 2013 In all domains of life, non-coding RNAs (ncRNAs) play a central role in cellular biology. In bacteria, the systematic discovery and analysis of ncRNAs revealed a large repertoire of regulatory transcripts, which among other characteristics is responsible for the high adaptability of prokaryotes.
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The RNA chaperone Hfq is important for growth and stress tolerance in Francisella novicida.
PLoS ONE, 2011 The RNA-binding protein Hfq is recognized as an important regulatory factor in a variety of cellular processes, including stress resistance and pathogenesis.
Jacob R Chambers, Kelly S Bender
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Apomorphine Targets the Pleiotropic Bacterial Regulator Hfq [PDF]
Antibiotics, 2021 Hfq is a bacterial regulator with key roles in gene expression. The protein notably regulates translation efficiency and RNA decay in Gram-negative bacteria, thanks to its binding to small regulatory noncoding RNAs. This property is of primary importance for bacterial adaptation and survival in hosts.
Florian Turbant +6 more
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Post-transcriptional regulator Hfq binds catalase HPII: crystal structure of the complex. [PDF]
PLoS ONE, 2013 We report a crystal structure of Hfq and catalase HPII from Escherichia coli. The post-transcriptional regulator Hfq plays a key role in the survival of bacteria under stress.
Koji Yonekura +5 more
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Models of Hfq interactions with small non-coding RNA in Gram-negative and Gram-positive bacteria
Frontiers in Cellular and Infection Microbiology, 2023 Hfq is required by many Gram-negative bacteria to chaperone the interaction between small non-coding RNA (sRNA) and mRNA to facilitate annealing. Conversely and despite the presence of Hfq in many Gram-positive bacteria, sRNAs in Gram-positive bacteria ...
Derrick Watkins, Dev Arya
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Prediction of Hfq in actinobacteria [PDF]
, 2015 Abstract Hfq is the bacterial orthologue of the eukaryotic (L)Sm family of proteins found across all domains of life and potentially an ancient protein, but it has not been found in all phyletic lines. A careful search successfully identified a distant hfq orthologue in the cyanobacteria leaving the actinobacteria as ...
Bora, Nagamani +2 more
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Effects of Hfq on the conformation and compaction of DNA [PDF]
Nucleic Acids Research, 2015 Hfq is a bacterial pleiotropic regulator that mediates several aspects of nucleic acids metabolism. The protein notably influences translation and turnover of cellular RNAs. Although most previous contributions concentrated on Hfq's interaction with RNA, its association to DNA has also been observed in vitro and in vivo.
Jiang, Kai +10 more
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Riboregulators and the role of Hfq in photosynthetic bacteria [PDF]
RNA Biology, 2014 Anoxygenic and oxygenic bacteria directly convert solar energy into biomass using photosynthesis. The formation and composition of photosynthetic complexes has to be tightly controlled in response to environmental conditions, as exposure to sunlight can be harmful due to the generation of reactive oxygen species and the damaging effects of UV ...
Hess, Wolfgang +4 more
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Hfq mutation confers increased cephalosporin resistance in Klebsiella pneumoniae [PDF]
Archives of Biological Sciences, 2017 Klebsiella pneumoniae (K. pneumoniae), is an opportunistic pathogen raising significant public health concerns owing to its multi-drug resistance. Hfq, one of the main RNA-binding proteins, is a key post-transcriptional regulator.
Li Xinran +7 more
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Clostridium difficile Hfq can replace Escherichia coli Hfq for most of its function [PDF]
RNA, 2014 A gene for the Hfq protein is present in the majority of sequenced bacterial genomes. Its characteristic hexameric ring-like core structure is formed by the highly conserved N-terminal regions. In contrast, the C-terminal forms an extension, which varies in length, lacks homology, and is predicted to be unstructured.
J., Caillet +3 more
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