Results 41 to 50 of about 6,621 (215)
The Hfq regulon of Neisseria meningitidis
FEBS Open Bio, 2017 The conserved RNA‐binding protein, Hfq, has multiple regulatory roles within the prokaryotic cell, including promoting stable duplex formation between small RNAs and mRNAs, and thus hfq deletion mutants have pleiotropic phenotypes. Previous proteome and transcriptome studies of Neisseria meningitidis have generated limited insight into differential ...
Robert A. G. Huis in ‘t Veld +4 more
openaire +3 more sources
Apomorphine Targets the Pleiotropic Bacterial Regulator Hfq [PDF]
Antibiotics, 2021 Hfq is a bacterial regulator with key roles in gene expression. The protein notably regulates translation efficiency and RNA decay in Gram-negative bacteria, thanks to its binding to small regulatory noncoding RNAs. This property is of primary importance for bacterial adaptation and survival in hosts.
Florian Turbant +6 more
openaire +3 more sources
Proceedings of the National Academy of Sciences of the United States of America, 2023 Significance Hfq is a central regulator in E. coli and many other bacteria, mediating small RNA-based regulation of mRNA translation and stability.
Xing Luo +6 more
semanticscholar +1 more source
Prediction of Hfq in actinobacteria [PDF]
, 2015 Abstract Hfq is the bacterial orthologue of the eukaryotic (L)Sm family of proteins found across all domains of life and potentially an ancient protein, but it has not been found in all phyletic lines. A careful search successfully identified a distant hfq orthologue in the cyanobacteria leaving the actinobacteria as ...
Bora, Nagamani +2 more
openaire +1 more source
The RNA chaperone Hfq is important for growth and stress tolerance in Francisella novicida.
PLoS ONE, 2011 The RNA-binding protein Hfq is recognized as an important regulatory factor in a variety of cellular processes, including stress resistance and pathogenesis.
Jacob R Chambers, Kelly S Bender
doaj +1 more source
Post-transcriptional regulator Hfq binds catalase HPII: crystal structure of the complex. [PDF]
PLoS ONE, 2013 We report a crystal structure of Hfq and catalase HPII from Escherichia coli. The post-transcriptional regulator Hfq plays a key role in the survival of bacteria under stress.
Koji Yonekura +5 more
doaj +1 more source
Effects of Hfq on the conformation and compaction of DNA [PDF]
Nucleic Acids Research, 2015 Hfq is a bacterial pleiotropic regulator that mediates several aspects of nucleic acids metabolism. The protein notably influences translation and turnover of cellular RNAs. Although most previous contributions concentrated on Hfq's interaction with RNA, its association to DNA has also been observed in vitro and in vivo.
Jiang, Kai +10 more
openaire +5 more sources
Riboregulators and the role of Hfq in photosynthetic bacteria [PDF]
RNA Biology, 2014 Anoxygenic and oxygenic bacteria directly convert solar energy into biomass using photosynthesis. The formation and composition of photosynthetic complexes has to be tightly controlled in response to environmental conditions, as exposure to sunlight can be harmful due to the generation of reactive oxygen species and the damaging effects of UV ...
Hess, Wolfgang +4 more
openaire +3 more sources
New Biotechnology, 2023 As a global regulatory mechanism, carbon catabolite repression allows bacteria and eukaryal microbes to preferentially utilize certain substrates from a mixture of carbon sources. The mechanism varies among different species.
Chunzhe Lu +5 more
semanticscholar +1 more source
The Pseudomonas aeruginosa CrcZ RNA interferes with Hfq-mediated riboregulation.
PLoS ONE, 2017 The RNA chaperone Hfq regulates virulence and metabolism in the opportunistic pathogen Pseudomonas aeruginosa. During carbon catabolite repression (CCR) Hfq together with the catabolite repression control protein Crc can act as a translational repressor ...
Elisabeth Sonnleitner +2 more
doaj +1 more source