Results 61 to 70 of about 6,621 (215)
Central role for RNase YbeY in Hfq-dependent and Hfq-independent small-RNA regulation in bacteria [PDF]
BMC Genomics, 2014 Conceptual parallels exist between bacterial and eukaryotic small-RNA (sRNA) pathways, yet relatively little is known about which protein may recognize and recruit bacterial sRNAs to interact with targets. In eukaryotes, Argonaute (AGO) proteins discharge such functions.
Pandey, Shree P. +5 more
openaire +4 more sources
Frontiers in Bioengineering and Biotechnology, 2022 Zymomonas mobilis is a promising microorganism for industrial bioethanol production. However, ethanol produced during fermentation is toxic to Z. mobilis and affects its growth and bioethanol production. Although several reports demonstrated that the RNA-
Yingie Tang +9 more
semanticscholar +1 more source
The Escherichia coli Hfq protein: an unattended DNA-transactions regulator
Frontiers in Molecular Biosciences, 2016 The Hfq protein was discovered in Escherichia coli as a host factor for bacteriophage Qβ RNA replication. Subsequent studies indicated that Hfq is a pleiotropic regulator of bacterial gene expression.
Grzegorz M Cech +6 more
doaj +1 more source
The Role of the Hfq Protein in Bacterial Resistance to Antibiotics: A Narrative Review
MicroorganismsThe antibiotic resistance of pathogenic microorganisms is currently one of most major medical problems, causing a few million deaths every year worldwide due to untreatable bacterial infections.
Sylwia Bloch +2 more
semanticscholar +1 more source
Translational regulation by Hfq–Crc assemblies emerges from polymorphic ribonucleoprotein folding
EMBO Journal, 2022 The widely occurring bacterial RNA chaperone Hfq is a key factor in the post‐transcriptional control of hundreds of genes in Pseudomonas aeruginosa. How this broadly acting protein can contribute to the regulatory requirements of many different genes ...
T. Dendooven +3 more
semanticscholar +1 more source
Regulation of fixLJ by Hfq Controls Symbiotically Important Genes in Sinorhizobium meliloti
Molecular Plant-Microbe Interactions, 2016 The RNA-binding chaperone Hfq plays critical roles in the establishment and functionality of the symbiosis between Sinorhizobium meliloti and its legume hosts. A mutation in hfq reduces symbiotic efficiency resulting in a Fix− phenotype, characterized by
Mengsheng Gao +3 more
doaj +1 more source
Interaction of the RNA chaperone Hfq with mRNAs: direct and indirect roles of Hfq in iron metabolism of Escherichia coli [PDF]
Molecular Microbiology, 2003 SummaryThe Escherichia coli Sm‐like host factor I (Hfq) is thought to play direct and indirect roles in post‐transcriptional regulation by targeting small regulatory RNAs and mRNAs. In this study, we have used proteomics to identify new mRNA targets of Hfq.
Vecerek, Branislav +4 more
openaire +3 more sources
No detectable effect of RNA-binding protein Hfq absence in
BMC Microbiology, 2007 Background The RNA-binding protein Hfq is involved in stress and virulence of several pathogens, probably due to its role as mediator in small RNA (sRNA)-mRNA interactions.
Bouloc Philippe +2 more
doaj +1 more source
Structural and biochemical studies on ATP binding and hydrolysis by the Escherichia coli RNA chaperone Hfq. [PDF]
PLoS ONE, 2012 In Escherichia coli the RNA chaperone Hfq is involved in riboregulation by assisting base-pairing between small regulatory RNAs (sRNAs) and mRNA targets. Several structural and biochemical studies revealed RNA binding sites on either surface of the donut
Hermann Hämmerle +6 more
doaj +1 more source
Non-Coding RNA, 2021 Many RNA-RNA interactions depend on molecular chaperones to form and remain stable in living cells. A prime example is the RNA chaperone Hfq, which is a critical effector involved in regulatory interactions between small RNAs (sRNAs) and cognate target ...
David Lalaouna +8 more
doaj +1 more source