Results 191 to 200 of about 6,261 (210)
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Supramolecular organization of Hfq-like proteins
Biochemistry (Moscow), 2015Bacterial Hfq proteins are structural homologs of archaeal and eukaryotic Sm/Lsm proteins, which are characterized by a 5-stranded β-sheet and an N-terminal α-helix. Previously, it was shown that archaeal Lsm proteins (SmAP) could produce long fibrils spontaneously, in contrast to the Hfq from Escherichia coli that could form similar fibrils only after
V N, Murina +7 more
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RNA Chaperones Step Out of Hfq’s Shadow
Trends in Microbiology, 2017The stability and function of regulatory small RNAs (sRNAs) often require a specialized RNA-binding protein called an RNA chaperone. Recent findings show that proteins containing a ProQ/FinO domain constitute a new class of RNA chaperones that could play key roles in post-transcriptional gene regulation throughout bacterial species.
Attaiech, Laetitia +2 more
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Bacterial Small Regulatory RNAs and Hfq Protein
Biochemistry (Moscow), 2015Small regulatory RNA (sRNA) is a unique noncoding RNA involved in regulation of gene expression in both eukaryotic and bacterial cells. This short review discusses examples of positive and negative translation regulation by sRNAs in bacteria and participation of Hfq in these processes. The importance of structure investigation of nucleotide-protein and
V N, Murina, A D, Nikulin
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Hfq: A Multifaceted RNA Chaperone Involved in Virulence
Future Microbiology, 2015Hfq has emerged in recent years as a master regulator of gene expression in bacteria, mainly due to its ability to mediate the interaction of small noncoding RNAs with their mRNA targets, including those related to virulence in Gram-negative bacteria.
Joana R, Feliciano +4 more
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Functional effects of variants of the RNA chaperone Hfq
Biochemical and Biophysical Research Communications, 2004The ring-shaped RNA chaperone Hfq has recently received much attention owing to its multiple roles in RNA metabolism. In this study we have performed a mutational analysis of the Escherichia coli hfq gene, and have studied the effects of amino acid substitutions at several positions in the Hfq protein as well as of C-terminal truncations on its role in
Sonnleitner, Elisabeth +7 more
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IDENTIFICATION AND CHARACTERIZATION OF HFQ AND HFQ-REGULATED SMALL RNAS IN ERWINIA AMYLOVORA
Acta Horticulturae, 2014Q. Zeng, G.W. Sundin
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Small RNAs and Hfq capture unfolded RNA target sites during transcription
Molecular Cell, 2023Margaret L Rodgers, Sarah A Woodson
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Heterotypic phase separation of Hfq is linked to its roles as an RNA chaperone
Cell Reports, 2022Tamar Szöke +2 more
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