Results 61 to 70 of about 13,098 (176)

Revealing topics and their evolution in biomedical literature using Bio-DTM: a case study of ginseng

Chinese Medicine, 2017
Background Valuable scientific results on biomedicine are very rich, but they are widely scattered in the literature. Topic modeling enables researchers to discover themes from an unstructured collection of documents without any prior annotations or ...
Qian Chen, Ni Ai, Jie Liao, Xin Shao, Yufeng Liu, Xiaohui Fan   +5 more
doaj   +1 more source

GeneToList: A Web Application to Assist with Gene Identifiers for the Non-Bioinformatics-Savvy Scientist

Biology, 2022
The increasing incorporation of omics technologies into biomedical research and translational medicine presents challenges to end users of the large and complex datasets that are generated by these methods.
Joshua D. Breidenbach, E. Francis Begue III, David J. Kennedy, Steven T. Haller   +3 more
doaj   +1 more source

Natural Language Query in the Biochemistry and Molecular Biology Domains Based on Cognition Search™ [PDF]

, 2008
Motivation: With the tremendous growth in scientific literature, it is necessary to improve upon the standard pattern matching style of the available search engines. Semantic NLP may be the solution to this problem.
Elizabeth J. Goldsmith, Kathleen Dahlgren, Radha Akella, Saurabh Mendiratta   +3 more
core   +2 more sources

A multi-gene signature predicts outcome in patients with pancreatic ductal adenocarcinoma. [PDF]

, 2014
© 2014 Haider et al.; licensee BioMed Central. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and ...
A Jemal, A Stathis, Ai Nagano, Aldo Scarpa, Ami Desai, AV Biankin, C Curtis, C Winter, Cancer Genome Atlas Research Network, CGA Network, Claude Chelala, CQ Zhu, D Cox, EA Collisson, F Maione, FM Buffa, G Zhang, H Huang, H Janouskova, H Pei, Hemant M Kocher, HH Wong, I Kovacevic, J Adachi, JA Tercero, JD Mosley, JK Stratford, John F Marshall, Jude Fitzgibbon, Jun Wang, K Yoshihara, L Badea, Laurent Dumartin, M Hidalgo, M Taniwaki, MA Tempero, MF Brennan, MM Al-Hawary, MW Muller, N Wasif, NF Li, Nicholas R Lemoine, NL Anderson, PA Perez-Mancera, PC Boutros, PG Febbo, PJ Campbell, Prabhu Arumugam, R Grutzmann, R Grutzmann, RR Plentz, S Jones, SJ Coleman, SV Srinivasan, Syed Haider, T Barrett, Tatjana Crnogorac-Jurcevic, Thorsten Hagemann, TR Donahue, VH Coupland   +59 more
core   +4 more sources

Modulation of Network Plasticity Opens Novel Therapeutic Possibilities in Cancer, Diabetes, and Neurodegeneration

Advanced Science, EarlyView.
Plasticity changes of molecular networks form a cellular learning process. Signaling network plasticity promotes cancer, metastasis, and drug resistance development. 55 plasticity‐related cancer drug targets are listed (20 having already approved drugs, 9 investigational drugs, and 26 being drug target candidates).
Márk Kerestély, István Narozsny, Levente Szarka, Daniel V. Veres, Peter Csermely, Dávid Keresztes   +5 more
wiley   +1 more source

Effect of Flecainide on Multifocal Ectopic Purkinje-Related Premature Contractions in an R814W SCN5A Carrier

JACC: Case Reports
Multifocal ectopic Purkinje-related premature contraction (MEPPC) is an autosomal dominant SCN5A channelopathy characterized by frequent multiform premature ventricular contractions originating from the His-Purkinje system.
Hisham Ahamed, MD, DM, Arun Gopi, MD, DM
doaj   +1 more source

Differential expression of zinc finger CCHC-type superfamily proteins in thyroid carcinoma and their associations with tumor immunity

Thyroid Research, 2023
Background The zinc-finger CCHC-type (ZCCHC) superfamily proteins are characterized by the shared sequence CX2-CX4-HX4-C and thought to own high affinity to single-stranded nucleic acids, particularly RNAs.
Yin Yin, Jing Chen, Qian Chen, Hongyan He, Nannan Zhu, Pengcheng Xia, Chunli Yu, Lingyun Meng   +7 more
doaj   +1 more source

Systematic nomenclature for the PLUNC/PSP/BSP30/SMGB proteins as a subfamily of the BPI fold-containing superfamily [PDF]

, 2011
We present the BPIFAn/BPIFBn systematic nomenclature for the PLUNC (palate lung and nasal epithelium clone)/PSP (parotid secretory protein)/BSP30 (bovine salivary protein 30)/SMGB (submandibular gland protein B) family of proteins, based on an adaptation
Ball, Bingle, Bingle, Bingle, C. Jeremy Craven, Chiang, Colin D. Bingle, Dear, Egland, Gautron, Inagawa, Khew-Goodall, Larkin, LeClair, Letunic, Madsen, McDonald, Mirels, Mulero, Rajan, Ruth L. Seal, Waterhouse, Weston, Wheeler, Wheeler, Yan   +25 more
core   +1 more source

Discovery and Differential Processing of HLA Class II-Restricted Minor Histocompatibility Antigen LB-PIP4K2A-1S and Its Allelic Variant by Asparagine Endopeptidase [PDF]

, 2020
Minor histocompatibility antigens are the main targets of donor-derived T-cells after allogeneic stem cell transplantation. Identification of these antigens and understanding their biology are a key requisite for more insight into how graft vs.
Bausenwein, Judith, Falkenburg, J. H. Frederik, Griffioen, Marieke, Honders, Maria W., Kremer, Andreas E., Kremer, Anita N., Kretschmann, Sascha, Lurvink, Ellie, Mackensen, Andreas, Mazzeo, Daniela, Rutten, Caroline E., van Bergen, Cornelis A. M., van der Meijden, Edith, Watts, Colin   +13 more
core   +2 more sources

A Novel Gain‐of‐Function ITPR1 Variant Associated With a Movement Disorder Characterized by Tremor and Dystonia

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT The 1,4,5‐trisphosphate receptor type 1 (ITPR1) gene encodes an endoplasmic reticulum calcium release channel, in which loss‐of‐function mutations have been associated with spinocerebellar ataxias and related neurological phenotypes. Only one gain‐of‐function mutation in the highly conserved suppressor domain of ITPR1 has been previously ...
Emilie T. Théberge, Bo Sun, Ruiwu Wang, Arezoo Mohajeri, Clara D. M. Van Karnebeek, Cornelius F. Boerkoel, Stephanie Huynh, Gabriella Horvath, S. R. Wayne Chen, Anna Lehman   +9 more
wiley   +1 more source