Prostatic intraepithelial neoplasia- the story evolves
Journal of Pathology of Nepal, 2016 Prostatic intraepithelial neoplasia is preneoplastic lesion described from early of this 20th century. PIN includes a spectrum of features ranging from low grade to high grade neoplasia. The studies are focused on their influence to predict the occurence
SV Pradhan, P Sharan
doaj +1 more source
Reduced alfa-MSH underlies hypothalamic ER-stress-induced hepatic gluconeogenesis [PDF]
, 2016 Alterations in ER homeostasis have been implicated in the pathophysiology of obesity and type-2 diabetes (T2D). Acute ER stress induction in the hypothalamus produces glucose metabolism perturbations.
Altirriba Gutiérrez, Jordi +15 more
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Comparison of the Prostate Imaging Reporting and Data System (PI-RADS) version 1 and 2 in a cohort of 245 patients with histopathological reference and long-term follow-up [PDF]
, 2016 Objective: To compare the performance of PI-RADSv2 with PI-RADSv1 in patients with elevated PSA before biopsy. Methods: 245 patients with elevated PSA underwent mpMRI before biopsy between May 2011 and December 2014 at 3.0 Tesla without endorectal coil.
Claeys, Tom +5 more
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CBP loss cooperates with PTEN haploinsufficiency to drive prostate cancer: implications for epigenetic therapy [PDF]
, 2014 Despite the high incidence and mortality of prostate cancer, the etiology of this disease is not fully understood. In this study, we develop functional evidence for CBP and PTEN interaction in prostate cancer based on findings of their correlate ...
Chen, Shuai +15 more
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The Role of Chronic Inflammation in Prostate Carcinogenesis: A Follow-Up Study
Annals of Urologic Oncology, 2019 Purpose To investigate the role of chronic inflammation in prostatic carcinogenesis with an emphasis on cancers of grade group 2 or above. Methods The presence/absence and extent of chronic inflammation and other relevant pathological findings were ...
Wei Chen +3 more
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Pathologic features of prostate cancer found at population-based screening with a four-year interval [PDF]
, 2001 BACKGROUND: The currently recommended frequency for prostate-specific antigen (PSA) screening tests for prostate cancer is 1 year, but the optimal screening interval is not known.
Boer, R. (Rob) +6 more
core +3 more sources
, 2014 The standard of care for patients suffering cancer often includes treatment with nucleoside analogues (NAs). NAs are internalized by cell-specific nucleobase/nucleoside transporters and, after enzymatic activation (often one or more phosphorylation steps)
Balzarini, Jan +2 more
core
The use of immunohistochemistry for diagnosis of prostate cancer [PDF]
, 2010 PURPOSE: Atypical glands (ASAP) are diagnosed in 5.0% of prostate biopsies, and cancer identification in a rebiopsy is higher than 40.0%. The use of antibodies to mark basal cells is currently a common practice, in order to avoid rebiopsies.
ANTUNES, Alberto A. +7 more
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World Journal of Surgical Oncology, 2004 Background Prostate stem cell antigen (PSCA) is a recently defined homologue of the Thy-1/Ly-6 family of glycosylphosphatidylinositol (GPI)-anchored cell surface antigens.
Wenlv Shen, Zhigang Zhao
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Evaluation of clinical outcomes of patients with HGPIN on prostate biopsy
European Urology Open Science, 2023 K. Daly +5 more
openaire +1 more source