Results 81 to 90 of about 2,747 (207)

The molecular and cellular origin of human prostate cancer [PDF]

, 2016
Prostate cancer is the most commonly diagnosed male malignancy. Despite compelling epidemiology, there are no definitive aetiological clues linking development to frequency.
Abate-Shen, Abrahamsson, Adler, Al-Hajj, Albini, Ammirante, An, An, Anderson, Anderson, Antonarakis, Ao, Armitage, Baca, Baker, Bapat, Barbieri, Barker, Barsky, Beck, Beltran, Ben-Neriah, Bergh, Bernstein, Berry, Bethel, Birkeland, Birnie, Blackwood, Bonnet, Borel, Bostwick, Bostwick, Boysen, Briganti, Bubendorf, Burkhardt, Caini, Cairns, Calabrese, Cancer Research UK, Carreira, Cesare, Chakkalakal, Chapman-Rothe, Chen, Cheshier, Choi, Chua, Clevers, Cloos, Cohen, Cohen, Collins, Collins, Conboy, Cooper, Culig, Culig, Cunha, Cunha, Dan Robinson, Das, Dawson, De Marzo, De Marzo, Dehm, Deng, Dermer, Ding, Don-Doncow, Donaldson, Dong, Ebelt, Eggener, Eminaga, Epstein, Eramo, Essers, Fang, Fassi Fehri, Fearon, Feinberg, Feng, Fialkow, Figueiredo, Foudi, Frame, Frame, Frame, Franco, Franks, Gan, Gannon, Gao, Gendrel, Gerlinger, Germann, Ghajar, Gibbs, Gimelbrant, Gleason, Gleave, Goardon, Goldstein, Gong, Goodwin, Gotay, Grasso, Grasso, Greaves, Grisanzio, Gundem, Guo, Gupta, Gurel, Guryanova, Gutierrez-Arcelus, Haapala, Haas, Haffner, Haffner, Haffner, Haffner, Hahn, Hall, Hall, Han, Hanahan, Hansel, He, Heaphy, Hecht, Heer, Herawi, Hermann, Hernandez, Heydt, Hjelmeland, Hong, Hong, Hovelson, Hrbacek, Hu, Huels, Huggins, Hurt, Hurt, Hägglöf, IACR, Iliopoulos, Iliou, Inaguma, Isaacs, Jafari, Jiao, Jin, John R. Packer, Johnston, Jones, Jones, Joseph, Karanika, Karantanos, Karthaus, Ke, Ke, Keller, Kelly, Kiel, Kim, Kooistra, Korpal, Kouzarides, Kovtun, Kreso, Krieger, Krieger, Kroon, Kulac, Kunderfranco, Lang, Lang, Lanie, Lapointe, Lark, Lavery, Lee, Lee, Leong, Leongamornlert, Li, Li, Li, Li, Lilja, Lin, Lin, Ling, Liu, Lo, Loeb, Luedeke, Lukacs, Ma, Mahmud, Maini, Maitland, Maitland, Maitland, Maitland, Mani, Marinov, Martin, Matsui, Meeker, Mehrotra, Menon, Merok, Metsalu, Metzger, Meyer, Michaud, Miyamoto, Mohan, Mounir, Munger, Nag, Nag, Nakai, Nakashima, Navarro, Nelson, Network, Nonn, Nonomura, Norman J. Maitland, Norrish, Nowell, O'Callaghan, O'Sullivan, Ohm, Olumi, Osman, Ousset, Park, Pascale, Patel, Patel, Patra, Patrawala, Patrawala, Pellacani, Penney, Perner, Perner, Perry, Peto, Pierce, Platz, Polson, Potten, Potter, Prince, Pritchard, Putzi, Qin, Rajan, Rando, Rane, Rane, Raval, Reik, Ricci-Vitiani, Ricci-Vitiani, Rich, Richardson, Riley, Risbridger, Robinson, Rodriguez, Rosa Mendoza, Ross-Adams, Roth, Ruska, Rutella, Sack, Sakr, Schiewer, Schober, Schroeder, Sfanos, Sfanos, Sfanos, Sfanos, Sharma, Sharma, Shen, Shibata, Shinohara, Shiozawa, Singh, Singh, Slaughter, Smith, Sneddon, Sommerfeld, Song, Song, Steinhauser, Stewart, Strand, Strasner, Stratton, Strickler, Sugimura, Suzuki, Tan, Tan, Tang, Taplin, Taylor, Tepper, Thompson, Ting, Ting, Toh, Tollervey, Tomasetti, Tomasetti, Tomasetti, Tomlins, Tomlins, Tomlinson, Tomlinson, Trock, True, Trumpp, Tuxhorn, Twillie, Urquidi, Ushijima, Valastyan, Van, Van Asperen, Vincent, Vindrieux, Visakorpi, Visvader, Vogelstein, Vral, Wang, Wang, Wang, Wang, Wang, Wang, Watt, Weinberger, Whitaker, Wild, Williams, Wilson, Woo, Wymenga, Xiang, Xiang, Xu, Yachida, Yamamoto, Yatabe, Yoshimoto, Yu, Zambrano, Zhang, Zhang, Zhang   +376 more
core   +1 more source

Clinical and histopathological parameters in transrectal ultrasound‐guided biopsies associated with tumor upgrading after radical prostatectomy: A comparative analysis of risk groups

The Prostate, Volume 84, Issue 12, Page 1146-1156, September 2024.
Abstract Background Thanks to technological advances, prostate cancer (PCa) can be diagnosed at a younger age. It is known that most of these patients are in the low‐intermediate risk group, and the histological grade of the tumor increases in half of those undergoing radical prostatectomy (Rp) compared to their diagnostic biopsies.
Mustafa Ozkaya, Muhammed Fatih Simsekoglu, Goktug Kalender, Kadir Can Sahin, Iclal Gurses   +4 more
wiley   +1 more source

KI-67 IMMUNOHISTOHEMICAL EXPRESSION IN PROSTATIC LESIONS

The Iraqi Journal of Medical Sciences, 2017
Background: The cell proliferation marker, ki-67, is a nuclear and nucleolar protein, which can be detected during all active phases of the cell cycle (G1, S, G2, and mitosis), but absent from cell resting phases.
Inas A. Rasheed, Alaa G. Hussein, Mohanad M. AbdulGhany   +2 more
doaj   +6 more sources

Morphologic patterns observed in prostate biopsy cases with discrepant grade group and molecular risk classification

The Prostate, Volume 84, Issue 11, Page 1076-1085, August 2024.
Abstract Background Molecular‐based risk classifier tests are increasingly being utilized by urologists and radiation oncologists to guide clinical decision making. The Decipher prostate biopsy test is a 22‐gene RNA biomarker assay designed to predict likelihood of high‐grade disease at radical prostatectomy and risk of metastasis and mortality.
Nancy Y. Greenland, Matthew R. Cooperberg, Peter R. Carroll, Janet E. Cowan, Jeffry P. Simko, Bradley A. Stohr, Emily Chan   +6 more
wiley   +1 more source

Conditional Expression of Human 15-Lipoxygenase-1 in Mouse Prostate Induces Prostatic Intraepithelial Neoplasia: The FLiMP Mouse Model

Neoplasia: An International Journal for Oncology Research, 2006
The incidence and mortality of prostate cancer (PCa) vary greatly in different geographic regions, for which lifestyle factors, such as dietary fat intake, have been implicated.
Uddhav P. Kelavkar, Anil V. Parwani, Scott B. Shappell, W. David Martin   +3 more
doaj   +1 more source

Atypical small acinar proliferation and two or more cores of high-grade intraepithelial neoplasia on a previous prostate biopsy are significant predictors of cancer during a transperineal template-guided saturation biopsy aimed at sampling one core for each 1 mL of prostate volume

Research and Reports in Urology, 2017
Yasushi Nakai,1 Nobumichi Tanaka,1 Makito Miyake,1 Shunta Hori,1 Yoshihiro Tatsumi,1,2 Yosuke Morizawa,1 Tomomi Fujii,2 Noboru Konishi,2 Kiyohide Fujimoto1 1Department of Urology, Nara Medical University, 2Department of Pathology, Nara Medical University,
Nakai Y, Tanaka N, Miyake M, Hori S, Tatsumi Y, Morizawa Y, Fujii T, Konishi N, Fujimoto K   +8 more
doaj  

PSA – biomarker, mis on muutnud eesnäärmehaiguste kliinilist käsitlust [PDF]

, 2009
Prostataspetsiifi line antigeen on enim kasutatav eesnäärmehaiguste marker kliinilises meditsiinis, mille tähtsus prostata biomarkerina avastati 1979. aastal. Oluline on teada, et PSA on eesnäärme-, mitte kasvajaspetsiifi line marker.
Ausmees, Kristo, Žarkovski, Mihhail
core   +2 more sources

Deciphering epigenetic regulation of enhancers in high‐risk prostate cancer

Genes, Chromosomes and Cancer, Volume 63, Issue 2, February 2024.
Abstract Prostate cancer (PCa) is associated with widespread promoter hypermethylation. We hypothesized that aberrant DNA methylation also targets gene enhancers, modulating their activity and contributing to disease etiology. A patient discovery set (n = 37) was used for differential methylation analysis and biomarker identification using the Infinium
A. V. Tuzova, B. Moran, N. M. Russell, S. Das, F. Delahaye, R. Silva, C. Barrett, R. W. G. Watson, A. O'Neill, W. M. Gallagher, J. Greally, A. S. Perry   +11 more
wiley   +1 more source

Evaluation of a short RNA within Prostate Cancer Gene 3 in the predictive role for future cancer using non-malignant prostate biopsies. [PDF]

, 2017
BACKGROUND: Prostate Cancer 3 (PCA3) is a long non-coding RNA (ncRNA) upregulated in prostate cancer (PCa). We recently identified a short ncRNA expressed from intron 1 of PCA3.
A. Aakula, A. Haese, A. Paziewska, A.A. Svoronos, B. Djavan, D. Hessels, D.J. Rosario, Derek J. Rosario, F.H. Schroder, G. Gandaglia, J. Klecka, J.B. de Kok, J.W. Catto, James W. F. Catto, Karl H. Pang, L.P. Bokhorst, M. Herawi, M. Salagierski, M.J. Bussemakers, M.M. Vedder, Mohammad Saleem, N. Mottet, R.A. Clarke, R.M. Drayton, S. Alinezhad, S. Miah, S.A. Tomlins, Susan L. Morgan   +27 more
core   +2 more sources

Molecular complexity of intraductal carcinoma of the prostate

Cancer Medicine, Volume 13, Issue 2, January 2024.
Abstract Intraductal carcinoma of the prostate (IDC‐P) is an aggressive subtype of prostate cancer characterized by the growth of tumor cells within the prostate ducts. It is often found alongside invasive carcinoma and is associated with poor prognosis.
Sha Zhu, Nanwei Xu, Hao Zeng
wiley   +1 more source