Results 91 to 100 of about 2,747 (207)
Reduced alfa-MSH underlies hypothalamic ER-stress-induced hepatic gluconeogenesis [PDF]
, 2016 Alterations in ER homeostasis have been implicated in the pathophysiology of obesity and type-2 diabetes (T2D). Acute ER stress induction in the hypothalamus produces glucose metabolism perturbations.
Altirriba Gutiérrez, Jordi +15 more
core +1 more source
Frontiers in Oncology, 2012 Introduction: 5-alpha reductase inhibitors can reduce the risk of prostate cancer but can be associated with significant side effects. A library of nomograms which predict the risk of clinical endpoints relevant to dutasteride treatment may help ...
Carvell eNguyen +3 more
doaj +1 more source
Prostatic intraepithelial neoplasia- the story evolves
Journal of Pathology of Nepal, 2016 Prostatic intraepithelial neoplasia is preneoplastic lesion described from early of this 20th century. PIN includes a spectrum of features ranging from low grade to high grade neoplasia. The studies are focused on their influence to predict the occurence
SV Pradhan, P Sharan
doaj +1 more source
, 2014 The standard of care for patients suffering cancer often includes treatment with nucleoside analogues (NAs). NAs are internalized by cell-specific nucleobase/nucleoside transporters and, after enzymatic activation (often one or more phosphorylation steps)
Balzarini, Jan +2 more
core
Comparison of the Prostate Imaging Reporting and Data System (PI-RADS) version 1 and 2 in a cohort of 245 patients with histopathological reference and long-term follow-up [PDF]
, 2016 Objective: To compare the performance of PI-RADSv2 with PI-RADSv1 in patients with elevated PSA before biopsy. Methods: 245 patients with elevated PSA underwent mpMRI before biopsy between May 2011 and December 2014 at 3.0 Tesla without endorectal coil.
Claeys, Tom +5 more
core +3 more sources
High expression of TROP2 characterizes different cell subpopulations in androgen-sensitive and androgenindependent prostate cancer cells [PDF]
, 2016 Progression of castration-resistant tumors is frequent in prostate cancer. Current systemic treatments for castration-resistant prostate cancer only produce modest increases in survival time and self-renewing Tumor-Initiating Cells (TICs) are suspected ...
Bioresource, APC +7 more
core +1 more source
The Role of Chronic Inflammation in Prostate Carcinogenesis: A Follow-Up Study
Annals of Urologic Oncology, 2019 Purpose To investigate the role of chronic inflammation in prostatic carcinogenesis with an emphasis on cancers of grade group 2 or above. Methods The presence/absence and extent of chronic inflammation and other relevant pathological findings were ...
Wei Chen +3 more
doaj +1 more source
A universal assay for detection of oncogenic fusion transcripts by oligo microarray analysis [PDF]
, 2009 Background The ability to detect neoplasia-specific fusion genes is important not only in cancer research, but also increasingly in clinical settings to ensure that correct diagnosis is made and the optimal treatment is chosen.
Skotheim, Rolf I +10 more
core +2 more sources
MRI to assess chemoprevention in transgenic adenocarcinoma of mouse prostate (TRAMP) [PDF]
, 2011 Background The current method to determine the efficacy of chemoprevention in TRAMP mouse model of carcinoma of prostate (CaP) is by extracting and weighing the prostate at different time points or by immunohistochemistry analysis.
Ali S Arbab +8 more
core +1 more source
World Journal of Surgical Oncology, 2004 Background Prostate stem cell antigen (PSCA) is a recently defined homologue of the Thy-1/Ly-6 family of glycosylphosphatidylinositol (GPI)-anchored cell surface antigens.
Wenlv Shen, Zhigang Zhao
doaj +1 more source