Results 81 to 90 of about 2,707 (196)

Morphologic patterns observed in prostate biopsy cases with discrepant grade group and molecular risk classification

open access: yesThe Prostate, Volume 84, Issue 11, Page 1076-1085, August 2024.
Abstract Background Molecular‐based risk classifier tests are increasingly being utilized by urologists and radiation oncologists to guide clinical decision making. The Decipher prostate biopsy test is a 22‐gene RNA biomarker assay designed to predict likelihood of high‐grade disease at radical prostatectomy and risk of metastasis and mortality.
Nancy Y. Greenland   +6 more
wiley   +1 more source

PSA – biomarker, mis on muutnud eesnäärmehaiguste kliinilist käsitlust [PDF]

open access: yes, 2009
Prostataspetsiifi line antigeen on enim kasutatav eesnäärmehaiguste marker kliinilises meditsiinis, mille tähtsus prostata biomarkerina avastati 1979. aastal. Oluline on teada, et PSA on eesnäärme-, mitte kasvajaspetsiifi line marker.
Ausmees, Kristo, Žarkovski, Mihhail
core   +2 more sources

Atypical small acinar proliferation and two or more cores of high-grade intraepithelial neoplasia on a previous prostate biopsy are significant predictors of cancer during a transperineal template-guided saturation biopsy aimed at sampling one core for each 1 mL of prostate volume

open access: yesResearch and Reports in Urology, 2017
Yasushi Nakai,1 Nobumichi Tanaka,1 Makito Miyake,1 Shunta Hori,1 Yoshihiro Tatsumi,1,2 Yosuke Morizawa,1 Tomomi Fujii,2 Noboru Konishi,2 Kiyohide Fujimoto1 1Department of Urology, Nara Medical University, 2Department of Pathology, Nara Medical University,
Nakai Y   +8 more
doaj  

Conditional Expression of Human 15-Lipoxygenase-1 in Mouse Prostate Induces Prostatic Intraepithelial Neoplasia: The FLiMP Mouse Model

open access: yesNeoplasia: An International Journal for Oncology Research, 2006
The incidence and mortality of prostate cancer (PCa) vary greatly in different geographic regions, for which lifestyle factors, such as dietary fat intake, have been implicated.
Uddhav P. Kelavkar   +3 more
doaj   +1 more source

Deciphering epigenetic regulation of enhancers in high‐risk prostate cancer

open access: yesGenes, Chromosomes and Cancer, Volume 63, Issue 2, February 2024.
Abstract Prostate cancer (PCa) is associated with widespread promoter hypermethylation. We hypothesized that aberrant DNA methylation also targets gene enhancers, modulating their activity and contributing to disease etiology. A patient discovery set (n = 37) was used for differential methylation analysis and biomarker identification using the Infinium
A. V. Tuzova   +11 more
wiley   +1 more source

MRI to assess chemoprevention in transgenic adenocarcinoma of mouse prostate (TRAMP) [PDF]

open access: yes, 2011
Background The current method to determine the efficacy of chemoprevention in TRAMP mouse model of carcinoma of prostate (CaP) is by extracting and weighing the prostate at different time points or by immunohistochemistry analysis.
Ali S Arbab   +8 more
core   +1 more source

Molecular complexity of intraductal carcinoma of the prostate

open access: yesCancer Medicine, Volume 13, Issue 2, January 2024.
Abstract Intraductal carcinoma of the prostate (IDC‐P) is an aggressive subtype of prostate cancer characterized by the growth of tumor cells within the prostate ducts. It is often found alongside invasive carcinoma and is associated with poor prognosis.
Sha Zhu, Nanwei Xu, Hao Zeng
wiley   +1 more source

Usefulness of Comparing of Magnetic Resonance Imaging (MRI) Findings Prior to Repeat Biopsy and Negative Initial Biopsy as a Decision-Making Method for Repeat Prostate Biopsy [PDF]

open access: yes, 2014
We retrospectively reviewed the data from a cohort of 44 patients with one initial negative transrectal ultrasound-guided prostate biopsy who underwent a repeat biopsy from 2006 to 2013.
今村, 正明   +5 more
core  

The REDUCE metagram: a comprehensive prediction tool for determining the utility of dutasteride chemoprevention in men at risk for prostate cancer

open access: yesFrontiers in Oncology, 2012
Introduction: 5-alpha reductase inhibitors can reduce the risk of prostate cancer but can be associated with significant side effects. A library of nomograms which predict the risk of clinical endpoints relevant to dutasteride treatment may help ...
Carvell eNguyen   +3 more
doaj   +1 more source

Evolution and oncological outcomes of a contemporary radical prostatectomy practice in a UK regional tertiary referral centre [PDF]

open access: yes, 2013
Objective To investigate the clinical and pathological trends over a ten-year period for robotic-assisted laparoscopic prostatectomy (RALP) in a UK regional tertiary referral centre.
Gnanapragasam, Vincent   +14 more
core   +1 more source

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