Multiple sclerosis: an example of pathogenic viral interaction? [PDF]
, 2017 A hypothesis is formulated on viral interaction between HHV-6A and EBV as a pathogenic mechanism in Multiple Sclerosis (MS). Evidence of molecular and genetic mechanisms suggests a link between HHV-6A infection and EBV activation in the brain of MS ...
Walter Fierz
core +1 more source
A murine herpesvirus closely related to ubiquitous human herpesviruses causes T-cell depletion [PDF]
, 2017 The human roseoloviruses human herpesvirus 6A (HHV-6A), HHV-6B, and HHV-7 comprise the Roseolovirus genus of the human Betaherpesvirinae subfamily. Infections with these viruses have been implicated in many
Beatrice Plougastel-Douglas +11 more
core +2 more sources
Evolutionary History of Endogenous Human Herpesvirus 6 Reflects Human Migration out of Africa. [PDF]
, 2021 Human herpesvirus 6A and 6B (HHV-6) can integrate into the germline, and as a result, ∼70 million people harbor the genome of one of these viruses in every cell of their body. Until now, it has been largely unknown if 1) these integrations are ancient, 2)
Aimola, Giulia +17 more
core +4 more sources
Human herpesvirus 6A and axonal injury before the clinical onset of multiple sclerosis [PDF]
, 2023 Recent research indicates that multiple sclerosis is preceded by a prodromal phase with elevated levels of serum neurofilament light chain (sNfL), a marker of axonal injury.
Alonso-Magdalena, Lucia +19 more
core
Prevalence of Chromosomally Integrated Human Herpesvirus 6 in Patients with Human Herpesvirus 6–Central Nervous System Dysfunction [PDF]
, 2014 We identified 37 hematopoietic cell transplantation recipients with human herpesvirus 6 (HHV-6) central nervous system dysfunction and tested donor-recipient pairs for chromosomally integrated HHV-6 (ciHHV-6).
Beranzoli, Laura +13 more
core +1 more source
Human herpesvirus 6A promotes glycolysis in infected T cells by activation of mTOR signaling.
PLoS Pathogens, 2020 Human herpesvirus 6 (HHV-6) is an important immunosuppressive and immunomodulatory virus worldwide. However, whether and how HHV-6 infection influences the metabolic machinery of the host cell to provide the energy and biosynthetic resources for virus ...
Zhisheng Wu +10 more
doaj +1 more source
Analyses of tissue culture adaptation of human Herpesvirus-6A by whole genome deep sequencing redefines the reference sequence and identifies virus entry complex changes [PDF]
, 2017 Tissue-culture adaptation of viruses can modulate infection. Laboratory passage and bacterial artificial chromosome (BAC)mid cloning of human cytomegalovirus, HCMV, resulted in genomic deletions and rearrangements altering genes encoding the virus entry ...
Escriva, E. +3 more
core +2 more sources
Human herpes virus type 6 (Orthoherpesviridae: Roseolovirus): features of epidemiology and diagnosis
Вопросы вирусологииHuman herpes virus 6A and human herpes virus 6B (HHV-6A and HHV-6B) are ubiquitous viruses. The spectrum of clinical manifestations of HHV-6A/B infections is quite wide.
Inara S. Saydullayeva +3 more
doaj +1 more source
Clinical and etiological aspects of human Betaherpesvirus infection 6: a review
Журнал инфектологии, 2022 The literature review is devoted to the modern concept of human betaherpesvirus 6 (human herpesvirus 6; HHV-6). The analysis of the literature mainly for the last five years was carried out.
N. S. Tian +2 more
doaj +1 more source
Advanced Optical Materials, EarlyView.Intramolecular bridge‐locking frustrates detrimental anti‐parallel packing in evaporated organic films. This design enhances net polar orientation, leading to a twofold off‐resonance increase in the second‐order nonlinear susceptibility (χ(2)) without electric‐field poling.
Pierre‐Luc Thériault +6 more
wiley +1 more source