Results 41 to 50 of about 55,098 (145)

Complete Genome Sequence of Germline Chromosomally Integrated Human Herpesvirus 6A and Analyses Integration Sites Define a New Human Endogenous Virus with Potential to Reactivate as an Emerging Infection

Viruses, 2016
Human herpesvirus-6A and B (HHV-6A, HHV-6B) have recently defined endogenous genomes, resulting from integration into the germline: chromosomally-integrated “CiHHV-6A/B”.
Joshua Tweedy, Maria Alexandra Spyrou, Max Pearson, Dirk Lassner, Uwe Kuhl, Ursula A. Gompels   +5 more
doaj   +1 more source

Associations of Inherited Chromosomally-Integrated Human Herpesvirus 6 With Dementia Incidence, Inflammation, and Other Dementia Risk Factors in the UK Biobank. [PDF]

J Med Virol
ABSTRACT The infection theory of dementia states that viral infections and chronic inflammation play a role in its pathogenesis. We aimed to test whether testing positive for inherited chromosomally‐integrated human herpesvirus 6 (iciHHV‐6) is associated with an increased dementia incidence, inflammation, and other dementia risk factors. We included n =
Qiya Z, Mandic M, Waterboer T, Ruijie X, Brenner H, Schöttker B.   +5 more
europepmc   +2 more sources

Image_2_DNA Sensors’ Signaling in NK Cells During HHV-6A, HHV-6B and HHV-7 Infection.TIFF

, 2020
ObjectivesThe host DNA sensor proteins TLR9, STING, IFI16 are central signaling molecules that control the innate immune response to cytosolic nucleic acids. Here we propose to investigate how Natural killer (NK) cell infection by human herpesvirus (HHV)-
Antonella Rotola (441846), Isabel Barao (8466057), Elisabetta Caselli (304287), Mariangela Sicolo (8466054), Irene Soffritti (6053267), Roberta Rizzo (304289), Daria Bortolotti (3159762), Valentina Gentili (2244499), Maria D’Accolti (1888321), Dario Di Luca (304297)   +9 more
core   +1 more source

Human herpesvirus 6A induces apoptosis of primary human fetal astrocytes via both caspase-dependent and -independent pathways

Virology Journal, 2011
Background Human herpesvirus 6 (HHV-6) is a T-lymphtropic and neurotropic virus that can infect various types of cells. Sequential studies reported that apoptosis of glia and neurons induced by HHV-6 might act a potential trigger for some central nervous
Gu Bin, Zhang Guo-Feng, Li Ling-Yun, Zhou Feng, Feng Dong-Ju, Ding Chuan-Lin, Chi Jing, Zhang Chun, Guo Dan-Dan, Wang Jing-Feng, Zhou Hong, Yao Kun, Hu Wei-Xing   +12 more
doaj   +1 more source

Analyses of germline, chromosomally integrated human herpesvirus 6A and B genomes indicate emergent infection and new inflammatory mediators.

, 2014
Human herpesvirus-6A (HHV-6A) is rarer than HHV-6B in many infant populations. However, they are similarly prevalent as germline, chromosomally integrated genomes (ciHHV-6A/B).
Spyrou, MA, Hubacek, P, Lassner, D, Kuhl, U, Gompels, UA, Tweedy, J   +5 more
core   +1 more source

Image_1_DNA Sensors’ Signaling in NK Cells During HHV-6A, HHV-6B and HHV-7 Infection.TIFF

, 2020
ObjectivesThe host DNA sensor proteins TLR9, STING, IFI16 are central signaling molecules that control the innate immune response to cytosolic nucleic acids. Here we propose to investigate how Natural killer (NK) cell infection by human herpesvirus (HHV)-
Antonella Rotola (441846), Isabel Barao (8466057), Elisabetta Caselli (304287), Mariangela Sicolo (8466054), Irene Soffritti (6053267), Roberta Rizzo (304289), Daria Bortolotti (3159762), Valentina Gentili (2244499), Maria D’Accolti (1888321), Dario Di Luca (304297)   +9 more
core   +1 more source

Functionalization‐Mediated Synthesis of Bridge‐Coordinated Fe Atoms on MoS2 Nanosheets for PEM Water Electrolyzers

Angewandte Chemie, Volume 138, Issue 39, 21 September 2026.
We report a functionalization‐mediated strategy to synthesize robust iron (Fe) atoms selectively coordinated at bridge sites on molybdenum disulfide (MoS2) nanosheets. The resulting b‐Fe‐MoS2 catalyst exhibits enhanced activity and durability for the hydrogen evolution reaction in proton exchange membrane water electrolyzers compared to atop ...
Zakaria Anfar, Haitham Maslouh, Yuwei Yang, Mathilde Moderne, Jiefeng Liu, Loïc Assaud, Mikhael Bechelany, Chrystelle Salameh, Kun Qi, Yuying Meng, Huali Wu, Ji Li, Nicholas M. Bedford, Damien Voiry   +13 more
wiley   +2 more sources

Copy Number Heterogeneity, Large Origin Tandem Repeats, and Interspecies Recombination in Human Herpesvirus 6A (HHV-6A) and HHV-6B Reference Strains. [PDF]

J Virol, 2018
Quantitative PCR is a diagnostic pillar for clinical virology testing, and reference materials are necessary for accurate, comparable quantitation between clinical laboratories.
Greninger AL, Roychoudhury P, Makhsous N, Hanson D, Chase J, Krueger G, Xie H, Huang ML, Saunders L, Ablashi D, Koelle DM, Cook L, Jerome KR.   +12 more
europepmc   +2 more sources

HHV-6A infection and menstrual cycle phases.

, 2016
a) HHV-6 DNA was searched by real time qPCR specific for U42 gene in endometrial biopsies of infertile women during proliferative, ovulatory and secretory phases.
Silvia Bolzani (3159759), Antonella Rotola (441846), Elisabetta Caselli (304287), Roberto Marci (311640), Roberta Rizzo (304289), Valentina Gentili (2244499), Daria Bortolotti (3159762), Giuseppe Lo Monte (3159756), Dario Di Luca (304297)   +8 more
core   +1 more source

Accumulation of viral telomeric signals during HHV-6A infection.

, 2020
A) Schematic representation of the HHV-6A/B genome. The unique (U) region of the HHV-6A/B genome (143–145 kbp) is flanked by two direct repeat sequences (8–10 kbp) referred to as DRL and DRR. The DRs contain perfect (TTAGGG)n and imperfect (het (TTAGGG)n)
Eros Lazzerini-Denchi (8748756), Benedikt B. Kaufer (6877832), Shella Gilbert-Girard (8748750), Annie Gravel (501989), Darren J. Wight (6877826), Vanessa Collin (8748753), Louis Flamand (501990)   +6 more
core   +1 more source