Chromatin Profiles of Chromosomally Integrated Human Herpesvirus-6A [PDF]
Frontiers in Microbiology, 2019 Human herpesvirus-6A (HHV-6A) and 6B (HHV-6B) are two closely related betaherpesviruses that are associated with various diseases including seizures and encephalitis.
Anthony J. Saviola +12 more
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The Telomeric Repeats of Human Herpesvirus 6A (HHV-6A) Are Required for Efficient Virus Integration. [PDF]
PLoS Pathogens, 2016 Human herpesvirus 6A (HHV-6A) and 6B (HHV-6B) are ubiquitous betaherpesviruses that infects humans within the first years of life and establishes latency in various cell types.
Nina Wallaschek +6 more
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Human Herpesvirus 6A Induces Dendritic Cell Death and HMGB1 Release without Virus Replication [PDF]
Pathogens, 2021 Human herpesvirus 6A (HHV-6A) is a common virus that has important immunomodulatory effects. Dendritic cells (DC) are key players in innate and adaptive immunity and are implicated in the pathogenesis of many human diseases, including infections.
Rasmus Gustafsson
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Human Herpesvirus 6A Is a Risk Factor for Multiple Sclerosis [PDF]
Frontiers in Immunology, 2022 The role for human herpesvirus (HHV)-6A or HHV-6B in multiple sclerosis (MS) pathogenesis has been controversial. Possibly because the damage of the virus infection may occur before onset of clinical symptoms and because it has been difficult to detect ...
Wangko Lundström, Rasmus Gustafsson
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Herpes simplex virus 1 rhombencephalitis in a patient with chromosomally integrated human herpesvirus-6A [PDF]
IDCases, 2020 Central nervous system infection caused by Herpes simplex virus 1 remains a significant cause of morbidity and mortality in transplant patients. Additionally, the clinical implications of the recently discovered Human herpesvirus 6A are still under ...
Raquel Silva +3 more
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Complete Genome Sequence of Germline Chromosomally Integrated Human Herpesvirus 6A and Analyses Integration Sites Define a New Human Endogenous Virus with Potential to Reactivate as an Emerging Infection [PDF]
Viruses, 2016 Human herpesvirus-6A and B (HHV-6A, HHV-6B) have recently defined endogenous genomes, resulting from integration into the germline: chromosomally-integrated “CiHHV-6A/B”.
Joshua Tweedy +5 more
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Modulatory effects on dendritic cells by human herpesvirus 6 [PDF]
Frontiers in Microbiology, 2015 Human herpesvirus 6A and 6B are β-herpesviruses approaching 100% seroprevalance worldwide. These viruses are involved in several clinical syndromes and have important immunomodulatory effects.
Rasmus eGustafsson +2 more
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ESCRT-III is recruited by human herpesvirus 6A nuclear egress complex to promote nuclear egress of the nucleocapsid [PDF]
Journal of VirologyHerpesviruses replicate their genomes and package them into capsids within the host cell nucleus. These capsids must then translocate from the nucleus to the cytoplasm through a process designated nuclear egress. The virus-encoded nuclear egress complex (
Aila Gulijiahani +5 more
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Novel marmoset (Callithrix jacchus) model of human Herpesvirus 6A and 6B infections: immunologic, virologic and radiologic characterization. [PDF]
PLoS Pathogens, 2013 Human Herpesvirus 6 (HHV-6) is a ubiquitous virus with an estimated seroprevalence of 95% in the adult population. HHV-6 is associated with several neurologic disorders, including multiple sclerosis, an inflammatory demyelinating disease affecting the ...
Emily Leibovitch +11 more
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Human Herpesvirus 6A Infection-Associated Acute Anterior Uveitis [PDF]
Journal of Inflammation ResearchHuiling Ma,1 Xinyun Wang,1 Ying Chen,1 Yun Zhang,2 Weina Ren,3 Yan Sheng1 1Department of Ophthalmology, the First Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, Zhejiang Province, 310003, People’s Republic of China; 2Department ...
Ma H +5 more
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