Recent developments in animal models for human herpesvirus 6A and 6B. [PDF]
Curr Opin Virol, 2014 International audienceProgress in the identification of suitable animal models for human herpesvirus (HHV)-6A and HHV-6B infections has been slow. Recently, new models have been established, mainly for HHV-6A, which reproduce some pathological features ...
Horvat B, Berges BK, Lusso P.
europepmc +7 more sources
Complete Genome Sequence of Germline Chromosomally Integrated Human Herpesvirus 6A and Analyses Integration Sites Define a New Human Endogenous Virus with Potential to Reactivate as an Emerging Infection [PDF]
Viruses, 2016 Human herpesvirus-6A and B (HHV-6A, HHV-6B) have recently defined endogenous genomes, resulting from integration into the germline: chromosomally-integrated “CiHHV-6A/B”.
Joshua Tweedy +5 more
doaj +2 more sources
Anti-human herpesvirus 6A/B IgG correlates with relapses and progression in multiple sclerosis. [PDF]
PLoS ONE, 2014 To analyze the titers of the IgG and IgM antibodies against human herpesvirus 6A/B (HHV-6A/B) in multiple sclerosis (MS) patients treated with different disease modified therapies (DMTs) along two-years of follow-up.We collected 2163 serum samples from ...
Isabel Ortega-Madueño +7 more
doaj +2 more sources
Acute Human Herpesvirus-6A infection of human mesothelial cells modulates HLA molecules
Archives of Virology, 2015 Human herpesvirus 6A (HHV-6A) causes ubiquitous infections, and has been associated with several diseases in immunosuppressed and immune dysregulated individuals.
RIZZO, Roberta +7 more
core +4 more sources
Modulation of the cytokine network in human adult astrocytes by human herpesvirus-6A
Journal of Neuroimmunology, 2005 Human herpesvirus-6A (HHV-6A) is a common pathogen whose role in CNS disorders including multiple sclerosis remains controversial. To understand how HHV-6A could influence inflammatory pathways in the CNS, we infected cultured human adult astrocytes and ...
Bsibsi, M. +6 more
core +4 more sources
Human herpesvirus 6A promotes glycolysis in infected T cells by activation of mTOR signaling. [PDF]
PLoS Pathogens, 2020 Human herpesvirus 6 (HHV-6) is an important immunosuppressive and immunomodulatory virus worldwide. However, whether and how HHV-6 infection influences the metabolic machinery of the host cell to provide the energy and biosynthetic resources for virus ...
Zhisheng Wu +10 more
doaj +2 more sources
Stabilization of Telomere G-Quadruplexes Interferes with Human Herpesvirus 6A Chromosomal Integration. [PDF]
J Virol, 2017 Human herpesvirus 6A and 6B (HHV-6A/B) can integrate their genomes into the telomeres of human chromosomes using a mechanism that remains poorly understood.
Gilbert-Girard S +6 more
europepmc +5 more sources
Modulatory effects on dendritic cells by human herpesvirus 6 [PDF]
Frontiers in Microbiology, 2015 Human herpesvirus 6A and 6B are β-herpesviruses approaching 100% seroprevalance worldwide. These viruses are involved in several clinical syndromes and have important immunomodulatory effects.
Rasmus eGustafsson +2 more
doaj +2 more sources
Animal models of human herpesvirus 6 infection [PDF]
Frontiers in Microbiology, 2013 Human herpesvirus (HHV)-6A and HHV-6B are two enveloped DNA viruses of β-herpesvirus family, infecting over 90% of the population and associated with several diseases, including exanthema subitum (for HHV-6B), multiple sclerosis and encephalitis ...
Joséphine eReynaud, Branka eHorvat
doaj +2 more sources
Human herpesvirus 6A and other risk factors for multiple sclerosis
Неврология, нейропсихиатрия, психосоматикаBased on a review of the literature, this article summarises the findings of original studies on the role of human herpesvirus 6A (HHV-6A) in the development of multiple sclerosis (MS).
A. E. Khrulev +6 more
doaj +2 more sources