LYMPHOPROLIFERATIVE SYNDROMES ASSOCIATED WITH HUMAN HERPESVIRUS-6A AND HUMAN HERPESVIRUS-6B [PDF]
Mediterranean Journal of Hematology and Infectious Diseases, 2018 Human herpesvirus 6A and 6B (HHV-6A and HHV-6B) have been noted since their discovery for their T-lymphotropism. Although it has proven difficult to determine the extent to which HHV-6A and HHV-6B are involved in the pathogenesis of many diseases ...
Eva Eliassen +3 more
doaj +5 more sources
Human herpesvirus 6A active infection in patients with autoimmune Hashimoto's thyroiditis [PDF]
Brazilian Journal of Infectious Diseases, 2019 Background: Hypothyroidism due to Hashimoto's thyroiditis (HT) is the commonest autoimmune endocrine illness in which antibodies against thyroid organ result in inflammation.
Noorossadat Seyyedi +9 more
doaj +6 more sources
Expression of the Human Herpesvirus 6A Latency-Associated Transcript U94A Disrupts Human Oligodendrocyte Progenitor Migration [PDF]
Scientific Reports, 2017 Progression of demyelinating diseases is caused by an imbalance of two opposing processes: persistent destruction of myelin and myelin repair by differentiating oligodendrocyte progenitor cells (OPCs).
Andrew Campbell +6 more
doaj +5 more sources
Features of Human Herpesvirus-6A and -6B Entry [PDF]
Advances in Virology, 2012 Human herpesvirus-6 (HHV-6) is a T lymphotropic herpesvirus belonging to the Betaherpesvirinae subfamily. HHV-6 was long classified into variants A and B (HHV-6A and HHV-6B); however, recently, HHV-6A and HHV-6B were reclassified as different species ...
Takahiro Maeki, Yasuko Mori
doaj +4 more sources
Viral Proteins U41 and U70 of Human Herpesvirus 6A Are Dispensable for Telomere Integration [PDF]
Viruses, 2018 Human herpesvirus-6A and -6B (HHV-6A and -6B) are two closely related betaherpesviruses that infect humans. Upon primary infection they establish a life-long infection termed latency, where the virus genome is integrated into the telomeres of latently ...
Darren J. Wight +5 more
doaj +2 more sources
Human herpesvirus 6A partially suppresses functional properties of DC without viral replication. [PDF]
PLoS ONE, 2013 Human herpesvirus 6A (HHV-6A) is a common virus with a worldwide distribution that has been associated with multiple sclerosis. Whether HHV-6A can replicate in dendritic cells (DC) and how the infection might modulate the functional properties of the ...
Rasmus K L Gustafsson +7 more
doaj +3 more sources
Human herpesvirus-6A/B binds to spermatozoa acrosome and is the most prevalent herpesvirus in semen from sperm donors. [PDF]
PLoS ONE, 2012 An analysis of all known human herpesviruses has not previously been reported on sperm from normal donors. Using an array-based detection method, we determined the cross-sectional frequency of human herpesviruses in semen from 198 Danish sperm donors ...
Maja D Kaspersen +5 more
doaj +5 more sources
Latency, Integration, and Reactivation of Human Herpesvirus-6
Viruses, 2017 Human herpesvirus-6A (HHV-6A) and human herpesvirus-6B (HHV-6B) are two closely related viruses that infect T-cells. Both HHV-6A and HHV-6B possess telomere-like repeats at the terminal regions of their genomes that facilitate latency by integration into
Shara N. Pantry, Peter G. Medveczky
doaj +3 more sources
Human herpesvirus 6A promotes glycolysis in infected T cells by activation of mTOR signaling. [PDF]
PLoS Pathogens, 2020 Human herpesvirus 6 (HHV-6) is an important immunosuppressive and immunomodulatory virus worldwide. However, whether and how HHV-6 infection influences the metabolic machinery of the host cell to provide the energy and biosynthetic resources for virus ...
Zhisheng Wu +10 more
doaj +2 more sources
Increased Serological Response Against Human Herpesvirus 6A Is Associated With Risk for Multiple Sclerosis [PDF]
Frontiers in Immunology, 2019 Human herpesvirus (HHV)-6A or HHV-6B involvement in multiple sclerosis (MS) etiology has remained controversial mainly due to the lack of serological methods that can distinguish the two viruses.
Elin Engdahl +37 more
doaj +2 more sources