Detection of HHV-5 HHV-6a HHV-6b and HHV-7 in the urine: potential use as a non-invasive diagnostic tool for immune profiling. [PDF]
Immun AgeingDecline in immune function with age has been studied extensively, but approaches to immune restoration have been hampered by the lack of simple methods of identifying individuals whose immune system is in decline.
Govind S +16 more
europepmc +2 more sources
Virus Research, 2022 HHV-6A is a neurotropic herpesvirus able to infect several CNS cells including astrocytes and primary neurons. Here we found that HHV-6A infection of astrocytoma cells, by reducing autophagy, increased ROS and induced ER stress, promoting the release of ...
Maria Anele Romeo +5 more
doaj +2 more sources
Impact of Host Telomere Length on HHV-6 Integration [PDF]
Viruses, 2022 Human herpesvirus 6A and 6B are two closely related viruses that infect almost all humans. In contrast to most herpesviruses, HHV-6A/B can integrate their genomes into the telomeres during the infection process.
Darren J. Wight +4 more
doaj +3 more sources
Features of Human Herpesvirus-6A and -6B Entry [PDF]
Advances in Virology, 2012 Human herpesvirus-6 (HHV-6) is a T lymphotropic herpesvirus belonging to the Betaherpesvirinae subfamily. HHV-6 was long classified into variants A and B (HHV-6A and HHV-6B); however, recently, HHV-6A and HHV-6B were reclassified as different species ...
Takahiro Maeki, Yasuko Mori
doaj +3 more sources
HHV-6A/6B Infection of NK Cells Modulates the Expression of miRNAs and Transcription Factors Potentially Associated to Impaired NK Activity. [PDF]
Front Microbiol, 2017 Natural killer (NK) cells have a critical role in controlling virus infections, and viruses have evolved several mechanisms to escape NK cell functions.
Rizzo R +5 more
europepmc +2 more sources
HHV-6A in vitro infection of thyrocytes and T cells alters the expression of miRNA associated to autoimmune thyroiditis. [PDF]
Virol J, 2017 BackgroundHuman herpesviruses have been hypothesized as environmental triggers in the development of autoimmune thyroid diseases (AITD), and in particular active human herpesvirus 6A (HHV-6A) infection was detected in thyrocytes of Hashimoto’s ...
Caselli E +6 more
europepmc +2 more sources
Copy Number Heterogeneity, Large Origin Tandem Repeats, and Interspecies Recombination in Human Herpesvirus 6A (HHV-6A) and HHV-6B Reference Strains. [PDF]
J Virol, 2018 Quantitative PCR is a diagnostic pillar for clinical virology testing, and reference materials are necessary for accurate, comparable quantitation between clinical laboratories.
Greninger AL +12 more
europepmc +2 more sources
Coinfection of human herpesviruses 6A (HHV-6A) and HHV-6B as demonstrated by novel digital droplet PCR assay. [PDF]
PLoS ONE, 2014 The human herpesviruses HHV-6A and HHV-6B have been associated with various neurologic disorders partly due to the detection of elevated viral DNA levels in patients compared to controls.
Emily C Leibovitch +6 more
doaj +2 more sources
HHV‐6A infection of endometrial epithelial cells affects immune profile and trophoblast invasion
American Journal of Reproductive Immunology, 2019 We first reported human herpesvirus (HHV)‐6A DNA presence in 43% of endometrial cells from women with idiopathic infertility, whereas no fertile control women harbored the virus.
D. Bortolotti +6 more
semanticscholar +4 more sources
The clinical and epidemiological features of HHV-6A and HHV-6B infections in children of Moscow
Детские инфекции (Москва), 2019 Human herpes virus type 6 (HHV-6) is the etiological agent of plenty diseases. The form of the developing pathology depends on the localization of the virus in T-lymphocytes and on virus type: HHV-6A or HHV-6B, but identification of the type is possible ...
M. Yu. Lysenkova +11 more
doaj +2 more sources