Results 31 to 40 of about 55,098 (145)
Possible Role of Human Herpesvirus 6 as a Trigger of Autoimmune Disease
The Scientific World Journal, 2013 Human herpesvirus 6 (HHV-6) infection is common and has a worldwide distribution. Recently, HHV-6A and HHV-6B have been reclassified into two distinct species based on different biological features (genetic, antigenic, and cell tropism) and disease ...
Francesco Broccolo +2 more
doaj +1 more source
Virus Research, 2022 HHV-6A is a neurotropic herpesvirus able to infect several CNS cells including astrocytes and primary neurons. Here we found that HHV-6A infection of astrocytoma cells, by reducing autophagy, increased ROS and induced ER stress, promoting the release of ...
Maria Anele Romeo +5 more
doaj +1 more source
Chromatin Profiles of Chromosomally Integrated Human Herpesvirus-6A
Frontiers in Microbiology, 2019 Human herpesvirus-6A (HHV-6A) and 6B (HHV-6B) are two closely related betaherpesviruses that are associated with various diseases including seizures and encephalitis.
Anthony J. Saviola +12 more
doaj +1 more source
Human herpesvirus 6A partially suppresses functional properties of DC without viral replication. [PDF]
PLoS ONE, 2013 Human herpesvirus 6A (HHV-6A) is a common virus with a worldwide distribution that has been associated with multiple sclerosis. Whether HHV-6A can replicate in dendritic cells (DC) and how the infection might modulate the functional properties of the ...
Rasmus K L Gustafsson +7 more
doaj +1 more source
Features of Human Herpesvirus-6A and -6B Entry
Advances in Virology, 2012 Human herpesvirus-6 (HHV-6) is a T lymphotropic herpesvirus belonging to the Betaherpesvirinae subfamily. HHV-6 was long classified into variants A and B (HHV-6A and HHV-6B); however, recently, HHV-6A and HHV-6B were reclassified as different species ...
Takahiro Maeki, Yasuko Mori
doaj +1 more source
Impact of Host Telomere Length on HHV-6 Integration
Viruses, 2022 Human herpesvirus 6A and 6B are two closely related viruses that infect almost all humans. In contrast to most herpesviruses, HHV-6A/B can integrate their genomes into the telomeres during the infection process.
Darren J. Wight +4 more
doaj +1 more source
Active HHV-6 Infection of Cerebellar Purkinje Cells in Mood Disorders
Frontiers in Microbiology, 2018 Early-life infections and associated neuroinflammation is incriminated in the pathogenesis of various mood disorders. Infection with human roseoloviruses, HHV-6A and HHV-6B, allows viral latency in the central nervous system and other tissues, which can ...
Bhupesh K. Prusty +11 more
doaj +1 more source
Image_3_DNA Sensors’ Signaling in NK Cells During HHV-6A, HHV-6B and HHV-7 Infection.TIF
, 2020 ObjectivesThe host DNA sensor proteins TLR9, STING, IFI16 are central signaling molecules that control the innate immune response to cytosolic nucleic acids. Here we propose to investigate how Natural killer (NK) cell infection by human herpesvirus (HHV)-
Antonella Rotola (441846) +9 more
core +1 more source
Human herpesvirus 6A promotes glycolysis in infected T cells by activation of mTOR signaling.
PLoS Pathogens, 2020 Human herpesvirus 6 (HHV-6) is an important immunosuppressive and immunomodulatory virus worldwide. However, whether and how HHV-6 infection influences the metabolic machinery of the host cell to provide the energy and biosynthetic resources for virus ...
Zhisheng Wu +10 more
doaj +1 more source
Image_4_DNA Sensors’ Signaling in NK Cells During HHV-6A, HHV-6B and HHV-7 Infection.TIF
, 2020 ObjectivesThe host DNA sensor proteins TLR9, STING, IFI16 are central signaling molecules that control the innate immune response to cytosolic nucleic acids. Here we propose to investigate how Natural killer (NK) cell infection by human herpesvirus (HHV)-
Antonella Rotola (441846) +9 more
core +1 more source