Results 31 to 40 of about 52,056 (173)
, 2007 Human herpesvirus 6A and 6B (HHV-6A and 6B) are considered to be T-lymphotropic viruses. The overall nucleotide sequence identity between the two variants is 90% and each differs by only nine variant-specific open reading frames. HHV-6A and 6B have often
Jenny Ahlqvist (19490293)
core +3 more sources
Human Herpesvirus 6A Is a Risk Factor for Multiple Sclerosis
Frontiers in Immunology, 2022 The role for human herpesvirus (HHV)-6A or HHV-6B in multiple sclerosis (MS) pathogenesis has been controversial. Possibly because the damage of the virus infection may occur before onset of clinical symptoms and because it has been difficult to detect ...
Wangko Lundström, Rasmus Gustafsson
doaj +1 more source
Novel marmoset (Callithrix jacchus) model of human Herpesvirus 6A and 6B infections: immunologic, virologic and radiologic characterization. [PDF]
PLoS Pathogens, 2013 Human Herpesvirus 6 (HHV-6) is a ubiquitous virus with an estimated seroprevalence of 95% in the adult population. HHV-6 is associated with several neurologic disorders, including multiple sclerosis, an inflammatory demyelinating disease affecting the ...
Emily Leibovitch +11 more
doaj +1 more source
Anti-human herpesvirus 6A/B IgG correlates with relapses and progression in multiple sclerosis. [PDF]
PLoS ONE, 2014 To analyze the titers of the IgG and IgM antibodies against human herpesvirus 6A/B (HHV-6A/B) in multiple sclerosis (MS) patients treated with different disease modified therapies (DMTs) along two-years of follow-up.We collected 2163 serum samples from ...
Isabel Ortega-Madueño +7 more
doaj +1 more source
Sensitive detection systems for infectious agents in xenotransplantation*
Xenotransplantation, EarlyView., 2020 Abstract Xenotransplantation of pig cells, tissues, or organs may be associated with transmission of porcine microorganisms, first of all of viruses, to the transplant recipient, potentially inducing a disease (zoonosis). I would like to define detection systems as the complex of sample generation, sample preparation, sample origin, time of sampling ...
Joachim Denner
wiley +1 more source
Complete Genome Sequence of the Human Herpesvirus 6A Strain AJ from Africa Resembles Strain GS from North America. [PDF]
, 2015 The genome sequence of human herpesvirus 6A (HHV-6A) strain AJ was determined in a comparison of target enrichment and long-range PCR using next-generation sequencing methodologies.
Spyrou, MA +5 more
core +1 more source
Human Herpesvirus 6A Induces Dendritic Cell Death and HMGB1 Release without Virus Replication
Pathogens, 2021 Human herpesvirus 6A (HHV-6A) is a common virus that has important immunomodulatory effects. Dendritic cells (DC) are key players in innate and adaptive immunity and are implicated in the pathogenesis of many human diseases, including infections.
Rasmus Gustafsson
doaj +1 more source
Identification of stimuli that enhance human herpesvirus 6A (HHV-6A) replication and reconstitution. [PDF]
J VirolABSTRACT Despite the availability of bacterial artificial chromosome (BAC) systems for human herpesvirus 6A (HHV-6A), reconstitution of infectious viruses is very challenging and time consuming. In this study, we developed approaches to improve the reconstitution process and enhance virus replication to overcome ...
Reich J +3 more
europepmc +3 more sources
Possible Role of Human Herpesvirus 6 as a Trigger of Autoimmune Disease
The Scientific World Journal, 2013 Human herpesvirus 6 (HHV-6) infection is common and has a worldwide distribution. Recently, HHV-6A and HHV-6B have been reclassified into two distinct species based on different biological features (genetic, antigenic, and cell tropism) and disease ...
Francesco Broccolo +2 more
doaj +1 more source
Virus Research, 2022 HHV-6A is a neurotropic herpesvirus able to infect several CNS cells including astrocytes and primary neurons. Here we found that HHV-6A infection of astrocytoma cells, by reducing autophagy, increased ROS and induced ER stress, promoting the release of ...
Maria Anele Romeo +5 more
doaj +1 more source