Results 21 to 30 of about 52,056 (173)

SARS-CoV-2 Infection Associated with HHV-6A Reactivation and an Inhibitory KIR2DL2/HLA-C1 Immunogenetic Profile [PDF]

Microorganisms
Natural killer (NK) cells are central to antiviral immunity through a balance of activating and inhibitory receptors, including killer immunoglobulin-like receptors (KIRs).
Sabrina Rizzo, Matteo Ferraresi, Giovanni Strazzabosco, Marcello Baroni, Juana Maria Sanz, Angelina Passaro, Daria Bortolotti, Roberta Rizzo, Giovanna Schiuma   +8 more
doaj   +2 more sources

Associations of Inherited Chromosomally-Integrated Human Herpesvirus 6 With Dementia Incidence, Inflammation, and Other Dementia Risk Factors in the UK Biobank. [PDF]

J Med Virol
ABSTRACT The infection theory of dementia states that viral infections and chronic inflammation play a role in its pathogenesis. We aimed to test whether testing positive for inherited chromosomally‐integrated human herpesvirus 6 (iciHHV‐6) is associated with an increased dementia incidence, inflammation, and other dementia risk factors. We included n =
Qiya Z, Mandic M, Waterboer T, Ruijie X, Brenner H, Schöttker B.   +5 more
europepmc   +2 more sources

Enhanced virus reconstitution of human herpesvirus 6A (HHV-6A)

BMC Methods
Background Human herpesvirus 6A (HHV-6A) is a member of the betaherpesvirus family and is associated with neurotropic diseases. Despite its clinical significance, HHV-6A research has been hampered by challenges in the generation of recombinant viruses.
Serdar, Dilan, Weißmann, Ann-Christin, Gravel, Annie, Beythien, Georg, Whyte, Melissa L., Hennig, Thomas, Cheng, Yingnan, Woude, Roosmarijn van der, Ospina, Jenny M., Hudson, Amy, Reich, Jana, Flamand, Louis, Kaufer, Benedikt B.   +12 more
core   +2 more sources

HHV-8-unrelated primary effusion-like lymphoma associated with clonal loss of inherited chromosomally-integrated human herpesvirus-6A from the telomere of chromosome 19q [PDF]

, 2016
Primary effusion lymphomas (PEL) are associated with human herpesvirus-8 (HHV-8) and usually occur in immunocompromised individuals. However, there are numerous reports of HHV-8-unrelated PEL-like lymphomas with unknown aetiology. Here we characterize an
Nicola J. Royle (7581539), Yan Huang (46805), A. J Bell (7666940), Sandrine Jayne (2947053), Martin J. Dyer (7638923), Enjie Zhang (7638905), Victoria E. Cotton (7595789), G. S. Wilkie (7666946), Alberto Hidalgo-Bravo (7638902), Aneela Majid (488055), E. P Nacheva (7666952), R. L. Siebert (7666955), Inga Kelpanides (7666958), R. F Jarrett (7666943), A. J. Davison (7666949)   +14 more
core   +8 more sources

Clinical and epidemiological features of infections caused by HHV-6A and HHV-6B [PDF]

Клиническая микробиология и антимикробная химиотерапия, 2018
Objective. To determine the detection rates of HHV-6A and HHV-6B compared to other herpes viruses in children of different age groups. Materials and Methods.
Lysenkova M.Yu., Karazhas N.V., Rybalkina T.N., Veselovsky P.A., Burmistrov E.M., Boshyan R.E., Melekhina E.V., Svitich O.A., Muzyka A.D., Petukhova E.V., Gorelov A.V.   +10 more
doaj   +3 more sources

The clinical and epidemiological features of HHV-6A and HHV-6B infections in children of Moscow [PDF]

Детские инфекции (Москва), 2019
Human herpes virus type 6 (HHV-6) is the etiological agent of plenty diseases. The form of the developing pathology depends on the localization of the virus in T-lymphocytes and on virus type: HHV-6A or HHV-6B, but identification of the type is possible ...
M. Yu. Lysenkova, E. V. Melekhina, N. V. Karazhas, O. A. Svitich, P. A. Veselovsky, T. N. Rybalkina, R. E. Boshyan, V. V. Kosenchuk, A. D. Muzyka, A. V. Gorelov, D. V. Usenko, M. Yu. Ivanova   +11 more
doaj   +2 more sources

The Telomeric Repeats of HHV-6A Do Not Determine the Chromosome into Which the Virus Is Integrated. [PDF]

Genes (Basel), 2023
Human herpes virus 6A (HHV-6A) is able to integrate into the telomeric and subtelomeric regions of human chromosomes representing chromosomally integrated HHV-6A (ciHHV-6A). The integration starts from the right direct repeat (DRR) region. It has been shown experimentally that perfect telomeric repeats (pTMR) in the DRR region are required for the ...
Kusakin AV, Goleva OV, Danilov LG, Krylov AV, Tsay VV, Kalinin RS, Tian NS, Eismont YA, Mukomolova AL, Chukhlovin AB, Komissarov AS, Glotov OS.   +11 more
europepmc   +3 more sources

Investigation of Inherited Chromosomally Integrated Human Herpesvirus-6A+ and -6B+ in a Patient with Ulipristal Acetate-Induced Fulminant Hepatic Failure

Viruses, 2021
Inherited chromosomally integrated (ici) human herpes virus 6 (HHV-6) is estimated to occur in 0.6–2.7% of people worldwide. HHV-6 comprises two distinct species: HHV-6A and HHV-6B. Both HHV-6A and HHV-6B integration have been reported. Several drugs are
Laure Izquierdo, Clémence M. Canivet, Eleonora De Martin, Teresa M. Antonini, Anne-Marie Roque-Afonso, Audrey Coilly, Claire Deback   +6 more
doaj   +1 more source

Diagnostic value of HHV-6A/B genotyping in immunocompromised adults. [PDF]

J Clin Microbiol
ABSTRACT Human herpesvirus 6 (HHV-6) comprises two genetically and biologically distinct species, HHV-6A and HHV-6B, yet species-level differentiation is rarely performed in clinical practice. We conducted a retrospective study of 119 immunocompromised adults with detectable HHV-6 DNA between ...
Rodríguez-Lorente V, Charry P, Guardia A, Fernández-Avilés F, Rovira M, Salas MQ, Martínez C, Rosiñol L, Bodro M, Pérez AB, Machuca I, Cervilla A, Mosquera MdM, Martínez MJ, Suárez-Lledó M, Marcos MÁ.   +15 more
europepmc   +2 more sources

Retraction to: A complex evolutionary relationship between HHV-6A and HHV-6B. [PDF]

Virus Evol, 2019
[This retracts the article DOI: 10.1093/ve/vez043.].
Forni D, Cagliani R, Clerici M, Pozzoli U, Sironi M.   +4 more
europepmc   +4 more sources