Results 21 to 30 of about 61,354 (196)

EBV/HHV-6A dUTPases contribute to myalgic encephalomyelitis/chronic fatigue syndrome pathophysiology by enhancing TFH cell differentiation and extrafollicular activities. [PDF]

JCI Insight, 2022
Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a chronic, debilitating, multisystem illness of unknown etiology for which no cure and no diagnostic tests are available. Despite increasing evidence implicating EBV and human herpesvirus 6A (
Cox BS, Alharshawi K, Mena-Palomo I, Lafuse WP, Ariza ME.   +4 more
europepmc   +2 more sources

Structural Models for Roseolovirus U20 And U21: Non-Classical MHC-I Like Proteins From HHV-6A, HHV-6B, and HHV-7. [PDF]

Front Immunol, 2022
Human roseolovirus U20 and U21 are type I membrane glycoproteins that have been implicated in immune evasion by interfering with recognition of classical and non-classical MHC proteins.
Weaver GC, Arya R, Schneider CL, Hudson AW, Stern LJ.   +4 more
europepmc   +2 more sources

Chromatin Profiles of Chromosomally Integrated Human Herpesvirus-6A [PDF]

Frontiers in Microbiology, 2019
Human herpesvirus-6A (HHV-6A) and 6B (HHV-6B) are two closely related betaherpesviruses that are associated with various diseases including seizures and encephalitis.
Anthony J. Saviola, Cosima Zimmermann, Michael P. Mariani, Sylvia A. Signorelli, Diana L. Gerrard, Joseph R. Boyd, Darren J. Wight, Guillaume Morissette, Annie Gravel, Isabelle Dubuc, Louis Flamand, Benedikt B. Kaufer, Seth Frietze   +12 more
doaj   +3 more sources

Corrigendum: Structural Models for Roseolovirus U20 And U21: Non-Classical MHC-I Like Proteins From HHV-6A, HHV-6B, and HHV-7. [PDF]

Front Immunol, 2022
[This corrects the article DOI: 10.3389/fimmu.2022.864898.].
Weaver GC, Arya R, Schneider CL, Hudson AW, Stern LJ.   +4 more
europepmc   +2 more sources

Novel marmoset (Callithrix jacchus) model of human Herpesvirus 6A and 6B infections: immunologic, virologic and radiologic characterization. [PDF]

PLoS Pathogens, 2013
Human Herpesvirus 6 (HHV-6) is a ubiquitous virus with an estimated seroprevalence of 95% in the adult population. HHV-6 is associated with several neurologic disorders, including multiple sclerosis, an inflammatory demyelinating disease affecting the ...
Emily Leibovitch, Jillian E Wohler, Sheila M Cummings Macri, Kelsey Motanic, Erin Harberts, María I Gaitán, Pietro Maggi, Mary Ellis, Susan Westmoreland, Afonso Silva, Daniel S Reich, Steven Jacobson   +11 more
doaj   +5 more sources

Active HHV-6 Infection of Cerebellar Purkinje Cells in Mood Disorders [PDF]

Frontiers in Microbiology, 2018
Early-life infections and associated neuroinflammation is incriminated in the pathogenesis of various mood disorders. Infection with human roseoloviruses, HHV-6A and HHV-6B, allows viral latency in the central nervous system and other tissues, which can ...
Bhupesh K. Prusty, Bhupesh K. Prusty, Nitish Gulve, Sheila Govind, Gerhard R. F. Krueger, Julia Feichtinger, Julia Feichtinger, Lee Larcombe, Richard Aspinall, Dharam V. Ablashi, Carla T. Toro, Carla T. Toro   +11 more
doaj   +4 more sources

Interactions of TTV with BKV, CMV, EBV, and HHV-6A and their impact on post-transplant graft function in kidney transplant recipients. [PDF]

Front Transplant
Background Mono and combined reactivation of latent viruses occurs frequently under immunosuppressive therapy in kidney transplant patients. Recently, monitoring torque teno virus (TTV) reactivation came more into focus as a potential biomarker for ...
Rosiewicz KS, Blazquez-Navarro A, Kaliszczyk S, Bauer C, Or-Guil M, Viebahn R, Zgoura P, Reinke P, Roch T, Hugo C, Westhoff T, Thieme C, Stervbo U, Babel N.   +13 more
europepmc   +2 more sources

Human Herpesvirus 6A (HHV-6A) Encephalitis in an Immunocompetent Patient and Its Association With Glioblastoma: A Case Report. [PDF]

Cureus
Human herpesvirus 6 (HHV-6) is a neurotropic virus capable of establishing latency in the central nervous system. While its reactivation is well-documented in immunocompromised individuals, its role in immunocompetent hosts remains unclear. Additionally,
Aleixo R, Sá R, Ramos I, Valente C.
europepmc   +2 more sources

Complete Genome Sequence of Germline Chromosomally Integrated Human Herpesvirus 6A and Analyses Integration Sites Define a New Human Endogenous Virus with Potential to Reactivate as an Emerging Infection [PDF]

Viruses, 2016
Human herpesvirus-6A and B (HHV-6A, HHV-6B) have recently defined endogenous genomes, resulting from integration into the germline: chromosomally-integrated “CiHHV-6A/B”.
Joshua Tweedy, Maria Alexandra Spyrou, Max Pearson, Dirk Lassner, Uwe Kuhl, Ursula A. Gompels   +5 more
doaj   +4 more sources

Paroxysmal Dyskinesias Secondary to HHV-6A Encephalitis: The First Case Report and Literature Review. [PDF]

Ann Clin Transl Neurol
Paroxysmal dyskinesias encompasses a spectrum of conditions marked by intermittent involuntary movements, with paroxysmal kinesigenic dyskinesias being the most common phenotype. Central nervous system infection is a rare cause of paroxysmal dyskinesias.
Wang Z, Li H, Du X, Wang Q, Zhang Y, Wang H.   +5 more
europepmc   +2 more sources