Chromosomal integration of HHV-6A during non-productive viral infection [PDF]
Scientific Reports, 2017 Human herpesvirus 6A (HHV-6A) and 6B (HHV-6B) are two different species of betaherpesviruses that integrate into sub-telomeric ends of human chromosomes, for which different prevalence rates of integration have been reported.
Nitish Gulve +3 more
doaj +3 more sources
HHV-6A Infection and Systemic Sclerosis: Clues of a Possible Association [PDF]
Microorganisms, 2019 Systemic sclerosis (SSc) is an autoimmune disease characterized by vasculopathy, excessive extracellular matrix deposition, and fibrosis of the skin and internal organs.
Elisabetta Caselli +7 more
doaj +4 more sources
Presence of HHV-6A in Endometrial Epithelial Cells from Women with Primary Unexplained Infertility. [PDF]
PLoS ONE, 2016 To elucidate the roles of human herpesvirus (HHV)-6 primary unexplained infertile women, a prospective randomized study was conducted on a cohort of primary unexplained infertile women and a cohort of control women, with at least one successful pregnancy.
Roberto Marci +8 more
doaj +3 more sources
SARS-CoV-2 Infection Associated with HHV-6A Reactivation and an Inhibitory KIR2DL2/HLA-C1 Immunogenetic Profile [PDF]
MicroorganismsNatural killer (NK) cells are central to antiviral immunity through a balance of activating and inhibitory receptors, including killer immunoglobulin-like receptors (KIRs).
Sabrina Rizzo +8 more
doaj +2 more sources
HHV-6A infection induces amyloid-beta expression and activation of microglial cells [PDF]
Alzheimer’s Research & Therapy, 2019 Background The control of viral infections in the brain involves the activation of microglial cells, the macrophages of the brain that are constantly surveying the central nervous system, and the production of amyloid-beta (Aβ) as an anti-microbial ...
Daria Bortolotti +4 more
doaj +2 more sources
Coinfection of human herpesviruses 6A (HHV-6A) and HHV-6B as demonstrated by novel digital droplet PCR assay. [PDF]
PLoS ONE, 2014 The human herpesviruses HHV-6A and HHV-6B have been associated with various neurologic disorders partly due to the detection of elevated viral DNA levels in patients compared to controls.
Emily C Leibovitch +6 more
doaj +2 more sources
The clinical and epidemiological features of HHV-6A and HHV-6B infections in children of Moscow [PDF]
Детские инфекции (Москва), 2019 Human herpes virus type 6 (HHV-6) is the etiological agent of plenty diseases. The form of the developing pathology depends on the localization of the virus in T-lymphocytes and on virus type: HHV-6A or HHV-6B, but identification of the type is possible ...
M. Yu. Lysenkova +11 more
doaj +2 more sources
Evolutionary analysis of exogenous and integrated HHV-6A/HHV-6B populations. [PDF]
Virus Evol, 2020 Human betaherpesviruses 6A and 6B (HHV-6A and HHV-6B) are highly prevalent in human populations. The genomes of these viruses can be stably integrated at the telomeres of human chromosomes and be vertically transmitted (inherited chromosomally integrated
Forni D +4 more
europepmc +2 more sources
gp96 Is Critical for both Human Herpesvirus 6A (HHV-6A) and HHV-6B Infections. [PDF]
Journal of Virology, 2020 Zhisheng Wu, Huamin Tang, Junli Jia
exaly +2 more sources
HHV-8-unrelated primary effusion-like lymphoma associated with clonal loss of inherited chromosomally-integrated human herpesvirus-6A from the telomere of chromosome 19q [PDF]
, 2016 Primary effusion lymphomas (PEL) are associated with human herpesvirus-8 (HHV-8) and usually occur in immunocompromised individuals. However, there are numerous reports of HHV-8-unrelated PEL-like lymphomas with unknown aetiology. Here we characterize an
Nicola J. Royle (7581539) +14 more
core +4 more sources