Results 11 to 20 of about 40,457 (178)

HHV-6A Infection and Systemic Sclerosis: Clues of a Possible Association [PDF]

Microorganisms, 2019
Systemic sclerosis (SSc) is an autoimmune disease characterized by vasculopathy, excessive extracellular matrix deposition, and fibrosis of the skin and internal organs.
Elisabetta Caselli, Irene Soffritti, Maria D’Accolti, Daria Bortolotti, Roberta Rizzo, Gianluca Sighinolfi, Dilia Giuggioli, Clodoveo Ferri   +7 more
doaj   +10 more sources

Chromosomal integration of HHV-6A during non-productive viral infection [PDF]

Scientific Reports, 2017
Human herpesvirus 6A (HHV-6A) and 6B (HHV-6B) are two different species of betaherpesviruses that integrate into sub-telomeric ends of human chromosomes, for which different prevalence rates of integration have been reported.
Nitish Gulve, Celina Frank, Maximilian Klepsch, Bhupesh K. Prusty   +3 more
doaj   +8 more sources

HHV-6A infection induces amyloid-beta expression and activation of microglial cells [PDF]

Alzheimer’s Research & Therapy, 2019
Background The control of viral infections in the brain involves the activation of microglial cells, the macrophages of the brain that are constantly surveying the central nervous system, and the production of amyloid-beta (Aβ) as an anti-microbial ...
Daria Bortolotti, Valentina Gentili, Antonella Rotola, Elisabetta Caselli, Roberta Rizzo   +4 more
doaj   +8 more sources

Presence of HHV-6A in Endometrial Epithelial Cells from Women with Primary Unexplained Infertility. [PDF]

PLoS ONE, 2016
To elucidate the roles of human herpesvirus (HHV)-6 primary unexplained infertile women, a prospective randomized study was conducted on a cohort of primary unexplained infertile women and a cohort of control women, with at least one successful pregnancy.
Roberto Marci, Valentina Gentili, Daria Bortolotti, Giuseppe Lo Monte, Elisabetta Caselli, Silvia Bolzani, Antonella Rotola, Dario Di Luca, Roberta Rizzo   +8 more
doaj   +9 more sources

Coinfection of human herpesviruses 6A (HHV-6A) and HHV-6B as demonstrated by novel digital droplet PCR assay. [PDF]

PLoS ONE, 2014
The human herpesviruses HHV-6A and HHV-6B have been associated with various neurologic disorders partly due to the detection of elevated viral DNA levels in patients compared to controls.
Emily C Leibovitch, Giovanna S Brunetto, Breanna Caruso, Kaylan Fenton, Joan Ohayon, Daniel S Reich, Steven Jacobson   +6 more
doaj   +4 more sources

Classification of HHV-6A and HHV-6B as distinct viruses. [PDF]

Arch Virol, 2014
Shortly after the discovery of human herpesvirus 6 (HHV-6), two distinct variants, HHV-6A and HHV-6B, were identified. In 2012, the International Committee on Taxonomy of Viruses (ICTV) classified HHV-6A and HHV-6B as separate viruses. This review outlines several of the documented epidemiological, biological, and immunological distinctions between HHV-
Ablashi D, Agut H, Alvarez-Lafuente R, Clark DA, Dewhurst S, DiLuca D, Flamand L, Frenkel N, Gallo R, Gompels UA, Höllsberg P, Jacobson S, Luppi M, Lusso P, Malnati M, Medveczky P, Mori Y, Pellett PE, Pritchett JC, Yamanishi K, Yoshikawa T.   +20 more
europepmc   +9 more sources

Evolutionary analysis of exogenous and integrated HHV-6A/HHV-6B populations. [PDF]

Virus Evol, 2020
AbstractHuman betaherpesviruses 6A and 6B (HHV-6A and HHV-6B) are highly prevalent in human populations. The genomes of these viruses can be stably integrated at the telomeres of human chromosomes and be vertically transmitted (inherited chromosomally integrated HHV-6A/HHV-6B, iciHHV-6A/iciHHV-6B).
Forni D, Cagliani R, Clerici M, Pozzoli U, Sironi M.   +4 more
europepmc   +8 more sources

HHV-6A in Syncytial Giant-Cell Hepatitis [PDF]

New England Journal of Medicine, 2008
Syncytial giant-cell hepatitis is a rare but severe form of hepatitis that is associated with autoimmune diseases, drug reactions, and viral infections. We used serologic, molecular, and immunohistochemical methods to search for an infectious cause in a case of syncytial giant-cell hepatitis that developed in a liver-transplant recipient who had latent
POTENZA, Leonardo, LUPPI, Mario, BAROZZI, Patrizia, ROSSI, Giulio, COCCHI, Stefania, Codeluppi, Mauro, Pecorari, Monica, MASETTI, Michele, DI BENEDETTO, Fabrizio, Gennari, William, PORTOLANI, Marinella, GERUNDA, Giorgio Enrico, LAZZAROTTO, TIZIANA, Landini, Maria Paola, Schulz, Thomas F., TORELLI, Giuseppe, GUARALDI, Giovanni   +16 more
openaire   +4 more sources

HHV-6A and HHV-6B in Autoimmune Disease [PDF]

, 2014
A role for HHV-6 has been proposed in several autoimmune disorders (ADs), including multiple sclerosis (MS), autoimmune connective tissue diseases, and Hashimoto's thyroiditis. There are several potential mechanisms by which HHV-6 might induce autoimmune responses.
Francesco Broccolo, BROCCOLO, FRANCESCO
openaire   +3 more sources

gp96 Is Critical for both Human Herpesvirus 6A (HHV-6A) and HHV-6B Infections [PDF]

Journal of Virology, 2020
Although new clinical importance has been revealed for human herpesviruses 6A (HHV-6A) and 6B, much is still unknown about the life cycles of these viruses in target cells. We identified a novel cellular factor, gp96, that is critical for both HHV-6A and -6B entry into host cells.
Wu Zhisheng, Huamin Tang
exaly   +5 more sources