Results 51 to 60 of about 40,457 (178)

Features of Human Herpesvirus-6A and -6B Entry

Advances in Virology, 2012
Human herpesvirus-6 (HHV-6) is a T lymphotropic herpesvirus belonging to the Betaherpesvirinae subfamily. HHV-6 was long classified into variants A and B (HHV-6A and HHV-6B); however, recently, HHV-6A and HHV-6B were reclassified as different species ...
Takahiro Maeki, Yasuko Mori
doaj   +1 more source

Impact of Host Telomere Length on HHV-6 Integration

Viruses, 2022
Human herpesvirus 6A and 6B are two closely related viruses that infect almost all humans. In contrast to most herpesviruses, HHV-6A/B can integrate their genomes into the telomeres during the infection process.
Darren J. Wight, Giulia Aimola, Georg Beythien, Louis Flamand, Benedikt B. Kaufer   +4 more
doaj   +1 more source

Copy Number Heterogeneity, Large Origin Tandem Repeats, and Interspecies Recombination in Human Herpesvirus 6A (HHV-6A) and HHV-6B Reference Strains. [PDF]

J Virol, 2018
Quantitative PCR is a diagnostic pillar for clinical virology testing, and reference materials are necessary for accurate, comparable quantitation between clinical laboratories.
Greninger AL, Roychoudhury P, Makhsous N, Hanson D, Chase J, Krueger G, Xie H, Huang ML, Saunders L, Ablashi D, Koelle DM, Cook L, Jerome KR.   +12 more
europepmc   +2 more sources

Accumulation of viral telomeric signals during HHV-6A infection. [PDF]

, 2020
A) Schematic representation of the HHV-6A/B genome. The unique (U) region of the HHV-6A/B genome (143–145 kbp) is flanked by two direct repeat sequences (8–10 kbp) referred to as DRL and DRR. The DRs contain perfect (TTAGGG)n and imperfect (het (TTAGGG)n)
Eros Lazzerini-Denchi (8748756), Benedikt B. Kaufer (6877832), Shella Gilbert-Girard (8748750), Annie Gravel (501989), Darren J. Wight (6877826), Vanessa Collin (8748753), Louis Flamand (501990)   +6 more
core   +1 more source

Functionalization‐Mediated Synthesis of Bridge‐Coordinated Fe Atoms on MoS2 Nanosheets for PEM Water Electrolyzers

Angewandte Chemie, EarlyView.
We report a functionalization‐mediated strategy to synthesize robust iron (Fe) atoms selectively coordinated at bridge sites on molybdenum disulfide (MoS2) nanosheets. The resulting b‐Fe‐MoS2 catalyst exhibits enhanced activity and durability for the hydrogen evolution reaction in proton exchange membrane water electrolyzers compared to atop ...
Zakaria Anfar, Haitham Maslouh, Yuwei Yang, Mathilde Moderne, Jiefeng Liu, Loïc Assaud, Mikhael Bechelany, Chrystelle Salameh, Kun Qi, Yuying Meng, Huali Wu, Ji Li, Nicholas M. Bedford, Damien Voiry   +13 more
wiley   +2 more sources

Active HHV-6 Infection of Cerebellar Purkinje Cells in Mood Disorders

Frontiers in Microbiology, 2018
Early-life infections and associated neuroinflammation is incriminated in the pathogenesis of various mood disorders. Infection with human roseoloviruses, HHV-6A and HHV-6B, allows viral latency in the central nervous system and other tissues, which can ...
Bhupesh K. Prusty, Bhupesh K. Prusty, Nitish Gulve, Sheila Govind, Gerhard R. F. Krueger, Julia Feichtinger, Julia Feichtinger, Lee Larcombe, Richard Aspinall, Dharam V. Ablashi, Carla T. Toro, Carla T. Toro   +11 more
doaj   +1 more source

Human herpesvirus 6A promotes glycolysis in infected T cells by activation of mTOR signaling.

PLoS Pathogens, 2020
Human herpesvirus 6 (HHV-6) is an important immunosuppressive and immunomodulatory virus worldwide. However, whether and how HHV-6 infection influences the metabolic machinery of the host cell to provide the energy and biosynthetic resources for virus ...
Zhisheng Wu, Junli Jia, Xianyi Xu, Mengyuan Xu, Guangyong Peng, Jingjing Ma, Xuefeng Jiang, Jialin Yao, Kun Yao, Lingyun Li, Huamin Tang   +10 more
doaj   +1 more source

Complete Genome Sequence of Germline Chromosomally Integrated Human Herpesvirus 6A and Analyses Integration Sites Define a New Human Endogenous Virus with Potential to Reactivate as an Emerging Infection

Viruses, 2016
Human herpesvirus-6A and B (HHV-6A, HHV-6B) have recently defined endogenous genomes, resulting from integration into the germline: chromosomally-integrated “CiHHV-6A/B”.
Joshua Tweedy, Maria Alexandra Spyrou, Max Pearson, Dirk Lassner, Uwe Kuhl, Ursula A. Gompels   +5 more
doaj   +1 more source

Human herpesvirus 6A induces apoptosis of primary human fetal astrocytes via both caspase-dependent and -independent pathways

Virology Journal, 2011
Background Human herpesvirus 6 (HHV-6) is a T-lymphtropic and neurotropic virus that can infect various types of cells. Sequential studies reported that apoptosis of glia and neurons induced by HHV-6 might act a potential trigger for some central nervous
Gu Bin, Zhang Guo-Feng, Li Ling-Yun, Zhou Feng, Feng Dong-Ju, Ding Chuan-Lin, Chi Jing, Zhang Chun, Guo Dan-Dan, Wang Jing-Feng, Zhou Hong, Yao Kun, Hu Wei-Xing   +12 more
doaj   +1 more source

HHV-6A and HHV-6B duplex ddPCR assay design and specificity validation. [PDF]

, 2014
(A) Primers were designed to amplify an 89 base pair region of U57, encoding the major capsid protein of HHV-6. The shared forward and reverse primers (in bold) amplify both HHV-6A and HHV-6B, while the probes are specific for each virus with a three ...
Joan Ohayon (541615), Breanna Caruso (541613), Giovanna S. Brunetto (541612), Steven Jacobson (67090), Kaylan Fenton (541614), Emily C. Leibovitch (541611), Daniel S. Reich (114120)   +6 more
core   +1 more source