Results 61 to 70 of about 61,354 (196)

Prevalence and risk factors for Betaherpesvirus DNAemia in children >3 weeks and <2 years of age admitted to a large referral hospital in sub-Saharan Africa [PDF]

, 2015
Background. Betaherpesviruses are established causes of morbidity and mortality in immunosuppressed patient groups but have been little studied in sub-Saharan Africa, the epicenter of the human immunodeficiency virus (HIV) pandemic.
A. Zumla, Achour, Anne de Pagter, Asano, Bates, Bates, Bello, C. Chabala, Chintu, Downing, Goussard, Hall, J. Tembo, Kasolo, Khansarinejad, Kovacs, L. Chilukutu, Lindquester, Liu, Lou, M. Bates, M. Chilufya, M. Kabwe, Manicklal, Milbradt, N. Mwaanza, Oliveira, Pellett, Salahuddin, Yamamoto, Yamanishi, Zerr   +31 more
core   +1 more source

HHV-6 in liver transplantation : A literature review [PDF]

, 2017
Human herpesvirus 6 (HHV-6A and HHV-6B) can cause primary infection or reactivate from latency in liver transplant recipients, which can result in a variety of clinical syndromes, including fever, hepatitis, encephalitis and higher rates of graft ...
Lautenschlager, Irmeli, Munoz, Flor M., Phan, Tuan L., Razonable, Raymund R.   +3 more
core   +1 more source

Human herpesvirus 6A promotes glycolysis in infected T cells by activation of mTOR signaling.

PLoS Pathogens, 2020
Human herpesvirus 6 (HHV-6) is an important immunosuppressive and immunomodulatory virus worldwide. However, whether and how HHV-6 infection influences the metabolic machinery of the host cell to provide the energy and biosynthetic resources for virus ...
Zhisheng Wu, Junli Jia, Xianyi Xu, Mengyuan Xu, Guangyong Peng, Jingjing Ma, Xuefeng Jiang, Jialin Yao, Kun Yao, Lingyun Li, Huamin Tang   +10 more
doaj   +1 more source

Human herpesvirus 6A and axonal injury before the clinical onset of multiple sclerosis [PDF]

, 2023
Recent research indicates that multiple sclerosis is preceded by a prodromal phase with elevated levels of serum neurofilament light chain (sNfL), a marker of axonal injury.
Alonso-Magdalena, Lucia, Andersen, Oluf, Bergström, Tomas, Biström, Martin, Blennow, Kaj, Butt, Julia, Fogdell-Hahn, Anna, Grut, Viktor, Gustafsson, Rasmus, Huang, Jesse, Jons, Daniel, Kockum, Ingrid, Lindam, Anna, Nilsson, Staffan, Olsson, Tomas, Salzer, Jonatan, Stridh, Pernilla, Sundström, Peter, Waterboer, Tim, Zetterberg, Henrik   +19 more
core  

Analyses of tissue culture adaptation of human Herpesvirus-6A by whole genome deep sequencing redefines the reference sequence and identifies virus entry complex changes [PDF]

, 2017
Tissue-culture adaptation of viruses can modulate infection. Laboratory passage and bacterial artificial chromosome (BAC)mid cloning of human cytomegalovirus, HCMV, resulted in genomic deletions and rearrangements altering genes encoding the virus entry ...
Escriva, E., Gompels, U., Topf, Maya, Tweedy, J.   +3 more
core   +2 more sources

Cell Host-Microbe Interactions: Turning Pathogen Mechanisms Into Cell's Advantages [PDF]

, 2013
Host-Pathogen Interaction is a very vast field of biological sciences, indeed every year many un- known pathogens are uncovered leading to an exponential growth of this field.
Avanzi, Simone <1982>
core   +1 more source

Evolutionary History of Endogenous Human Herpesvirus 6 Reflects Human Migration out of Africa. [PDF]

, 2021
Human herpesvirus 6A and 6B (HHV-6) can integrate into the germline, and as a result, ∼70 million people harbor the genome of one of these viruses in every cell of their body. Until now, it has been largely unknown if 1) these integrations are ancient, 2)
Aimola, Giulia, Aswad, Amr, Breuer, Judith, Charnock-Jones, D Stephen, Greninger, Alexander L, Hill, Joshua, Huang, Meei-Li, Kaufer, Benedikt B, Lager, Susanne, Lassner, Dirk, Parrish, Nicholas F, Roychoudhury, Pavitra, Schultheiss, Heinz-Peter, Smith, Gordon CS, Venturini, Cristina, Wight, Darren, Xie, Hong, Zimmermann, Cosima   +17 more
core   +4 more sources

Human herpesvirus 6A induces apoptosis of primary human fetal astrocytes via both caspase-dependent and -independent pathways

Virology Journal, 2011
Background Human herpesvirus 6 (HHV-6) is a T-lymphtropic and neurotropic virus that can infect various types of cells. Sequential studies reported that apoptosis of glia and neurons induced by HHV-6 might act a potential trigger for some central nervous
Gu Bin, Zhang Guo-Feng, Li Ling-Yun, Zhou Feng, Feng Dong-Ju, Ding Chuan-Lin, Chi Jing, Zhang Chun, Guo Dan-Dan, Wang Jing-Feng, Zhou Hong, Yao Kun, Hu Wei-Xing   +12 more
doaj   +1 more source

Human herpes virus type 6 (Orthoherpesviridae: Roseolovirus): features of epidemiology and diagnosis

Вопросы вирусологии
Human herpes virus 6A and human herpes virus 6B (HHV-6A and HHV-6B) are ubiquitous viruses. The spectrum of clinical manifestations of HHV-6A/B infections is quite wide.
Inara S. Saydullayeva, Dmitry S. Tikhomirov, Mikhail Y. Drokov, Tatiana A. Tupoleva   +3 more
doaj   +1 more source

The HCMV‐encoded miR‐UL36‐3p promotes angiogenesis of endothelial cells by downregulating FOXO3

Animal Models and Experimental Medicine, EarlyView.
This illustration shows the role of hcmv‐miR‐UL36‐3p in endothelial cell angiogenesis. During productive infection, endothelial cells express HCMV‐encoded miRNAs. Viral hcmv‐miR‐UL36‐3p promotes endothelial cell proliferation, migration, and capillary tube formation by directly targeting and downregulating FOXO3. The pro‐angiogenic activity of hcmv‐miR‐
Chen Wang, Mengyu Li, Guosheng Li, Hao Zhang, Cheng Wang, Chen‐Yu Zhang   +5 more
wiley   +1 more source