Results 81 to 90 of about 61,354 (196)
A viral APOBEC3 antagonist distinguishes HHV-6A from HHV-6B
Human herpesviruses exhibit diverse pathogenic outcomes and the molecular reasons are not fully understood. Human herpesvirus 6B (HHV-6B) causes exanthema subitum and encephalitis, whereas the closely related HHV-6A is typically asymptomatic.
Jun Arii +11 more
doaj +1 more source
Human herpesvirus-6A (HHV-6A) and −6B (HHV-6B) might be involved in the etiopathogenesis of multiple sclerosis (MS), especially the HHV-6A. We aim at assessing, for the first time in the scientific literature, the HHV-6A/B microRNAs in MS patients.
María I. Domínguez-Mozo +5 more
doaj +1 more source
A one‐step bulk integration of the surfactant Tween 20 into PDMS enables intrinsic and water‐triggered hydrophilicity. Combined molecular simulations and experiments reveal a dual mechanism where bound and mobile Tween 20 molecules cooperatively induce self‐activating, stretch‐tolerant, and long‐term wettability, supporting self‐driven liquid transport,
Haotian Cha +8 more
wiley +1 more source
Role for the shelterin protein TRF2 in human herpesvirus 6A/B chromosomal integration.
Human herpesviruses 6A and 6B (HHV-6A/B) are unique among human herpesviruses in their ability to integrate their genome into host chromosomes. Viral integration occurs at the ends of chromosomes within the host telomeres.
Shella Gilbert-Girard +6 more
doaj +1 more source
DNA Virus Detection in Olfactory Neuroblastomas Using Targeted Enrichment NGS
ABSTRACT A variety of malignancies can be found in the sinonasal tract including the nasal cavity, paranasal sinuses, and skull base. Many of these are attributed to viruses, for example, carcinomas with the presence of transcriptionally active high‐risk human papillomavirus, as well as Epstein–Barr virus associated malignant lymphoepithelial carcinoma
Maria K. Jauhiainen +7 more
wiley +1 more source
Latency, Integration, and Reactivation of Human Herpesvirus-6
Human herpesvirus-6A (HHV-6A) and human herpesvirus-6B (HHV-6B) are two closely related viruses that infect T-cells. Both HHV-6A and HHV-6B possess telomere-like repeats at the terminal regions of their genomes that facilitate latency by integration into
Shara N. Pantry, Peter G. Medveczky
doaj +1 more source
Nano‐ and Micro‐Sized Solid Materials Used as Antiviral Agents
Due to the rise of viral infections in humans and possible viral outbreaks, the use of nano‐ or micro‐sized materials as antiviral agents is rapidly increasing. This review explores their antiviral properties against RNA and DNA viruses, either as a prevention or a treatment tool, by delving into their mechanisms of action and how to properly assess ...
Orfeas‐Evangelos Plastiras +6 more
wiley +1 more source
Human Cytomegalovirus Inhibitor AL18 Also Possesses Activity against Influenza A and B Viruses [PDF]
AL18, an inhibitor of human cytomegalovirus DNA polymerase, was serendipitously found to also block the interaction between the PB1 and PA polymerase subunits of influenza A virus.
Cruciani, Gabriele +6 more
core +2 more sources
GP96 interacts with HHV-6 during viral entry and directs it for cellular degradation.
CD46 and CD134 mediate attachment of Human Herpesvirus 6A (HHV-6A) and HHV-6B to host cell, respectively. But many cell types interfere with viral infection through rapid degradation of viral DNA.
Bhupesh K Prusty +4 more
doaj +1 more source
HHV-6A and HHV-6B are neurotropic viruses able to dysregulate autophagy and activate ER stress/UPR in several cell types. The appropriate functioning of these processes is required for cell homeostasis, particularly in post-mitotic cells such as neuronal
M. Romeo +5 more
semanticscholar +1 more source

