Results 81 to 90 of about 2,937 (141)

Guidelines from the 2017 European Conference on Infections in Leukaemia for management of HHV-6 infection in patients with hematologic malignancies and after hematopoietic stem cell transplantation

open access: yesHaematologica, 2019
Of the two human herpesvirus 6 (HHV-6) species, human herpesvirus 6B (HHV-6B) encephalitis is an important cause of morbidity and mortality after allogeneic hematopoietic stem cell transplant. Guidelines for the management of HHV-6 infections in patients
Katherine N Ward   +9 more
doaj   +1 more source

“Systematic review of HHV-6 and febrile seizures: Should the ER include it in the viral panel?”

open access: yesJournal of Clinical Virology Plus
Background: Human herpesvirus 6 (HHV-6), particularly subtype B, is a common viral infection in childhood and the cause of roseola infantum. Beyond its dermatologic effects, HHV-6B is an important yet often underrecognized contributor to febrile seizures
Shaina Gagadam, Valerie Foy
doaj   +1 more source

Atomic structure of the human herpesvirus 6B capsid and capsid-associated tegument complexes

open access: yesNature Communications, 2019
Human Herpesvirus 6B (HHV-6) can cause fever, diarrhea and roseola rash. Here the authors present a cryoEM approach to image crude, minimally purified virus samples and employ it to determine the atomic structures of HHV-6B capsid and capsid-associated ...
Yibo Zhang   +10 more
doaj   +1 more source

Clinical Relevance of High HHV-6B Viral Load in Immunocompromised Host

open access: yesImmunology and Genetics Journal
The peculiarity of the chromosomally integrated form of human herpesvirus type 6 (ciHHV-6) is its wide distribution (up to 1% of the population), the possibility of transmission by inheritance, the problem of diagnosis, including issues of differential diagnosis with the acute form of HHV-6 infection, which, in turn, makes it difficult to resolve the ...
Elena Kishkurno   +3 more
openaire   +1 more source

The immediate-early protein 1 of human herpesvirus 6B interacts with NBS1 and inhibits ATM signaling

open access: yesEMBO Reports
Viral infection often trigger an ATM serine/threonine kinase (ATM)-dependent DNA damage response in host cells that suppresses viral replication. Viruses evolved different strategies to counteract this antiviral surveillance system.
Vanessa Collin   +11 more
doaj   +1 more source

Human Herpes Virus-6 (HHV-6) Reactivation after Hematopoietic Cell Transplant and Chimeric Antigen Receptor (CAR)- T Cell Therapy: A Shifting Landscape

open access: yesViruses
HHV-6B reactivation affects approximately half of all allogeneic hematopoietic cell transplant (HCT) recipients. HHV-6B is the most frequent infectious cause of encephalitis following HCT and is associated with pleiotropic manifestations in this setting,
Eleftheria Kampouri   +2 more
doaj   +1 more source

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