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KSHV/HHV8-mediated hematologic diseases

Blood, 2022
Abstract Kaposi sarcoma (KS) herpesvirus (KSHV), also known as human herpesvirus 8, is the causal agent of KS but is also pathogenetically related to several lymphoproliferative disorders, including primary effusion lymphoma (PEL)/extracavitary (EC) PEL, KSHV-associated multicentric Castleman disease (MCD), KSHV+ diffuse large B-cell ...
Ethel Cesarman   +2 more
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Multiple Myeloma and HHV8 Infection

Blood, 1998
To the Editor: In a recent issue of BLOOD Said et al[1][1] reported the presence of human herpesvirus 8 (HHV8) DNA in bone marrow stromal dendritic cells of patients with multiple myeloma and acquired immunodeficiency syndrome patients with plasmocytosis.
G, Cathomas   +5 more
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HHV8 and female Kaposi's sarcoma

The Journal of Pathology, 1997
Kaposi's sarcoma (KS) is an enigmatic tumour of uncertain histogenesis. Epidemiological data have long suggested that KS may be caused by an infectious agent, possibly sexually transmitted. Following the documentation of human herpesvirus 8 (HHV8) and its strong association with all forms of KS, it now appears that the putative agent has at last been ...
M M, Kennedy   +8 more
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HHV8-Associated Lymphoproliferative Disorders

2020
Human herpesvirus type 8 (HHV8) causes several lymphoproliferative disorders, including multicentric Castleman disease (MCD), HHV8-positive diffuse large B-cell lymphoma (DLBCL), HHV8-positive germinotropic lymphoproliferative disorder (GLPD), and primary effusion lymphoma (PEL).
Wei Wang, L. Jeffrey Medeiros
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A bibliometric analysis of KSHV/HHV8 research

COLLNET Journal of Scientometrics and Information Management, 2020
A bibliometric analysis was conducted to evaluate the global scientific output of KSHV/HHV8 research in the Science Citation Index Expanded from 1991 to 2016.
Yi-Fen Wang   +2 more
openaire   +1 more source

Diagnosis of hhv8 infection

Hematology Meeting Reports, 2009
Before 1994, the idea that an infectious agent played a role in Kaposi’s sarcoma, was nothing more than a strong suspicion. In that year, human herpesvirus 8 (HHV8) was identified in KS tissue. HHV8, also known as Kaposi’s sarcoma-associated Herpesvirus (KSHV), belongs to the Gammaherpesvirinae subfamily of genus Rhadinovirus and is the first member of
openaire   +1 more source

HHV6, HHV7, and HHV8

2017
HHV6, HHV7, and HHV8, the newest human herpes virus, are not identified in ocular disorders. However, we have recently noticed that these viral infections are implicated in ocular inflammatory diseases including uveitis, endophthalmitis, corneal inflammation (keratitis, endotheliitis), and optic neuropathy because these virus-positive cases are found ...
Sunao Sugita, Tomoyuki Inoue
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Kshv/hhv8-associated lymphomas

Hematology Meeting Reports, 2009
It was only after the discovery of KSHV/HHV8, that primary effusion lymphoma (PEL) could be recognized as a distinct entity, thanks to its consistent association with HHV-8 infection. As a consequence, PEL has been included in the recent WHO lymphoma classification, within the group of lymphomas occurring more specifically in HIV positive patients. PEL
openaire   +1 more source

Differences in the frequency and function of HHV8-specific CD8 T cells between asymptomatic HHV8 infection and Kaposi sarcoma

Blood, 2006
AbstractIt is unclear how the immune response controls human herpesvirus 8 (HHV8; also known as Kaposi sarcoma–associated herpesvirus [KSHV]) replication and thereby prevents Kaposi sarcoma (KS). We compared CD8 T-cell responses to HHV8 latent (K12) and lytic (glycoprotein B, ORF6, ORF61, and ORF65) antigens in patients who spontaneously controlled the
Marion, Lambert   +9 more
openaire   +2 more sources

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