Results 191 to 200 of about 19,695,084 (324)

Investigations of the Evolved Molecular Basis for Terpenoid Biosynthesis in Marine Sponges

Advanced Science, EarlyView.
Confirming and extending a previous observation in another Bubarida sponge, genomic and functional analyses of A. cavernosa reveal that sponges retain the mevalonate pathway and employ single α‐domain T1TSs and UbiA‐type TSs for terpenoid biosynthesis. The absence of T1TSs clustering with other biosynthetic genes tentatively suggests, based on limited ...
Fangyan Chen, Bao Chen, Wenhui Zhang, Guifang Sun, Yao Zhao, Jianpeng Zhang, Baofu Xu   +6 more
wiley   +1 more source

Identifying the principal mechanism of star formation feedback. [PDF]

Sci Adv
Li C, Li R, Qiu K, Krco M, Li D, Wang H, Lyu X, Duan Y, Fang M, Chen X, Wang L, Feng H, Zhang S, Zhang M, Zhang S, Cao Y, Wang Y, Gong Y, Du F, Chen Z, Su Y, Ma Y, Xing Y, Zheng Y, Zhang T, Niu S, Li C, Liu J, Zhang Z, Guo Y.   +29 more
europepmc   +1 more source

The Mitogen‐Activated Protein Kinase GhNTF3 Modulates the Arbuscular Mycorrhizal Symbiosis‐Immunity Trade‐Off in Cotton by Regulating Salicylic Acid Biosynthesis

Advanced Science, EarlyView.
AM symbiosis induces GhWAK13 to promote fungal colonization. GhNTF3 negatively regulates symbiosis by promoting SA biosynthesis. GhWAK13 sequesters GhNTF3 at the membrane, limiting its nuclear translocation and relieving SA‐mediated suppression. Under Verticillium stress, GhNTF3 enters the nucleus and interacts with GhJAZ6 to activate SA signaling ...
Shuangjie Jia, Jingshang Wen, Jihang Li, Meina Feng, Yiming He, Ruojun Liu, Qian Liu, Junli Zhang, Kai Cheng, Xiangyu Zhang, Xiao Zhang   +10 more
wiley   +1 more source

Optimized M-SHAKE Constraint Implementations for GPU-Accelerated Molecular Dynamics: Balancing Precision and Performance Across Architectures. [PDF]

J Comput Chem
Jung J, La Torre DU, Kobayashi C, Ozaki K, Sugita Y.   +4 more
europepmc   +1 more source

CHST1 Drives Immunotherapy Resistance in Triple‐Negative Breast Cancer by Orchestrating an Immunosuppressive Microenvironment via the NKRF–CCL20–Macrophage Axis

Advanced Science, EarlyView.
Proposed model of CHST1‐associated immune remodeling in triple‐negative breast cancer. In CHST1‐low tumors, greater nuclear accumulation of NKRF is associated with repression of an NF‐κB‐related CCL20 transcriptional program and an immune‐inflamed microenvironment.
Shu‐Hao Jiang, Xiao‐Han Ying, Ruo‐Qing Wang, Qun Zhang, Li Chen, Zhi‐Ming Shao, Jun‐Jie Li   +6 more
wiley   +1 more source

Bacterial Meningitis Epidemiology in Burkina Faso and Niger-High-Risk Countries in the Meningitis Belt of Sub-Saharan Africa, 2015-2023. [PDF]

J Infect Dis
Pinell-McNamara VA, Ouédraogo HS, Kafando L, Sani O, Issoufou AA, Tassiou EI, Sanou M, Tarbangdo F, Bita A, Fernandez K, Kekeisen-Chen J, Cureau N, Aboubacar A, Acho F, Aké F, Childs L, Farrar JL, Gbaguidi CAP, Kambou F, Katsande R, Kobayashi M, Latt A, Lingani C, Marjuki H, McGee L, Neatherlin J, Novak RT, Ouattara M, Pezzoli L, Soeters HM, Tonde I, Tamboura M, Mamane Z, Yameogo I, McNamara LA.   +34 more
europepmc   +1 more source

In Vivo Direct Reprogramming: Current Progress and Future Prospects from Mechanisms to Therapeutic Application

Advanced Science, EarlyView.
This review examines the potential of in vivo direct reprogramming in regenerative medicine for functional tissue restoration, highlighting the role of tissue‐resident cues in generating functionally mature reprogrammed cells from lineage‐related cells. It contains a discussion on mechanisms, reprogramming factors, delivery approaches, and applications
Rishabh Deo Singh, Mauro Calvoli, Kyeong Kyu Kim   +2 more
wiley   +1 more source

Lower Hospitalization Rates During Fluid Management with Relative Blood Volume Monitoring: A Retrospective Cohort Analysis. [PDF]

J Clin Med
Ficociello LH, Zhou M, Xiao M, Han H, Anger MS, Hymes JL, Chatoth D.   +6 more
europepmc   +1 more source

An Engineered HR1‐Stem Helix‐HR2 Trimeric Platform for Developing Broad‐Spectrum Coronavirus Vaccines

Advanced Science, EarlyView.
Sun et al. report a self‐assembling trimeric subunit vaccine platform termed RHS, which integrates the JN.1 receptor‐binding domain (RBD) with the heptad repeat 1 (HR1), stem helix (SH), and heptad repeat 2 (HR2) regions. The SARS‐CoV‐2 RHS vaccine elicits variant‐reactive RBD‐specific antibodies and cross‐reactive SH‐specific antibodies against ...
Xikui Sun, Junhao Fan, Xiaolu Xie, Yuting Shi, Xiaoqing Liu, Tiefeng Xu, Sidi Yang, Keda Shi, Chengshu Xie, Shixiong Li, Siwen Chen, Ruoxi Cai, Ping He, Yuzhen Ye, Tao Chen, Xiancai Ma, Chunmei Li, Jingyou Yu, Deyin Guo   +18 more
wiley   +1 more source

Effective Solvent‐Engineered All‐Inorganic CsPbI2Br Perovskite Solar Cells

Advanced Science, EarlyView.
All‐inorganic CsPbI2Br perovskite composition has gathered a lot of attention in recent years due to its thermal robustness, convenience for space applications as well as for the all‐perovskite triple junction applications as a top cell due to its wide‐bandgap (1.9 eV) nature.
Rajarshi Roy, Mahdi Malekshahi Byranvand, Tim Kodalle, Maximilian Krappel, Laxman Gouda, Stephan Boehringer, Chittaranjan Das, Mayank Kedia, Carolin M. Sutter‐Fella, Michael Saliba   +9 more
wiley   +1 more source