Results 41 to 50 of about 19,695,084 (324)

The Mechanism of the Neuroprotective Effect of Kynurenic Acid in the Experimental Model of Neonatal Hypoxia–Ischemia: The Link to Oxidative Stress

Antioxidants, 2021
The over-activation of NMDA receptors and oxidative stress are important components of neonatal hypoxia–ischemia (HI). Kynurenic acid (KYNA) acts as an NMDA receptor antagonist and is known as a reactive oxygen species (ROS) scavenger, which makes it a ...
Ewelina Bratek-Gerej, Apolonia Ziembowicz, Jakub Godlewski, Elzbieta Salinska   +3 more
doaj   +1 more source

Changes in Amplitude-integrated Electroencephalograms in Piglets During Selective Mild Head Cooling After Hypoxia-ischemia

Pediatrics and Neonatology, 2014
Amplitude-integrated electroencephalogram (aEEG) is a simplified, alternative means of monitoring cerebral function and may be more useful clinically in some situations than conventional EEG.
Ji-Mei Wang, Guo-Fu Zhang, Wen-Hao Zhou, Ze-Dong Jiang, Xiao-Mei Shao   +4 more
doaj   +1 more source

Hearing characteristics of infantile-onset Pompe disease after early enzyme-replacement therapy

Orphanet Journal of Rare Diseases, 2021
Background Studies suggest that enzyme-replacement therapy (ERT) is crucial to the survival of patients with infantile-onset Pompe disease (IOPD). Hearing impairment (HI) is one of the clinical sequelae observed in long-term survivors.
Chien-Yu Hsueh, Chii-Yuan Huang, Chia-Feng Yang, Chia-Chen Chang, Wei-Sheng Lin, Hsiu-Lien Cheng, Shang-Liang Wu, Yen-Fu Cheng, Dau-Ming Niu   +8 more
doaj   +1 more source

The effect of hypothalamic involvement and growth hormone treatment on cardiovascular risk factors during the transition period in patients with childhood-onset craniopharyngioma [PDF]

Annals of Pediatric Endocrinology & Metabolism, 2022
Purpose Hypothalamic damage may increase the risk of adulthood obesity and cardiovascular disease in patients with craniopharyngioma. We evaluated the effects of hypothalamic involvement (HI) and growth hormone (GH) discontinuation on cardiovascular risk
Sang Hee Park, Yun Jeong Lee, Jung-Eun Cheon, Choong Ho Shin, Hae Woon Jung, Young Ah Lee   +5 more
doaj   +1 more source

Assessment of the Therapeutic and Anticonvulsive Efficacy of a Drug Combination Consisting of Trihexyphenidyle and HI-6 in Soman-Poisoned Rats

Acta Medica, 2004
1. The influence of two anticholinergic drugs (atropine, trihexyphenidyle) on the effectiveness of antidotal treatment to eliminate soman-induced lethal effects and convulsions was studied in rats. 2.
Jiří Kassa, Ivan Samnaliev
doaj   +1 more source

Efficacy of antidotes (midazolam, atropine and HI-6) on nerve agent induced molecular and neuropathological changes

BMC Neuroscience, 2014
BackgroundRecent alleged attacks with nerve agent sarin on civilians in Syria indicate their potential threat to both civilian and military population.
G. RamaRao, Prachiti Afley, J. Acharya, B. K. Bhattacharya   +3 more
semanticscholar   +1 more source

Therapeutic Efficacy of Different Antidotal Mixtures Against Poisoning with GF-Agent in Mice

Acta Medica, 2004
The toxicity of cyclohexyl methylphosphonofluoridate (GF-agent; cyclosarin) and therapeutic efficacy of four oximes (trimedoxime, methoxime, obidoxime and HI-6) in combination with atropine or benactyzine (BNZ) was studied in mice.
Lucie Bartošová, Gabriela Kunešová, Kamil Kuča, Josef Vachek   +3 more
doaj   +1 more source

Effectiveness and safety of hydrogen inhalation as an adjunct treatment in Chinese type 2 diabetes patients: A retrospective, observational, double-arm, real-life clinical study

Frontiers in Endocrinology, 2023
AimTo analyze the effectiveness and safety of hydrogen inhalation (HI) therapy as an adjunct treatment in Chinese type 2 diabetes mellitus (T2DM) patients in a real-life clinical setting.MethodsThis observational, non-interventional, retrospective ...
Ziyi Zhao, Hongxiang Ji, Yunsheng Zhao, Zeyu Liu, Ruitao Sun, Yuquan Li, Tongshang Ni   +6 more
doaj   +1 more source

Nanoparticulate transport of oximes over an in vitro blood-brain barrier model [PDF]

, 2010
Background: Due to the use of organophosphates (OP) as pesticides and the availability of OP-type nerve agents, an effective medical treatment for OP poisonings is still a challenging problem.
Tikva Vogel, Kreuter, Jörg (Prof. Dr.), Sascha Wien, Zensi, Anja, Kufleitner, Jürgen, Jörg Kreuter, Wien, Sascha, Jürgen Kufleitner, Bungert, Judith, Wagner, Sylvia, Judith Bungert, Dadparvar, Miriam, Vogel, Tikva, Anja Zensi, Sylvia Wagner, Worek, Franz, Miriam Dadparvar, Hagen von Briesen, Briesen, Hagen von, Franz Worek   +19 more
core   +2 more sources

Kiinnityssovite HI-TEC kaivinkoneelle [PDF]

, 2021
Tämän opinnäytetyön tarkoituksena oli suunnitella HI-TEC kaivuulaitteelle välyksetön pikakiinnityssovite, joka on kiinnitettynä Valtra N143 traktorin runkoon.
Karesto, Timo
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