scDIAGRAM: detecting chromatin compartments from individual single-cell Hi-C matrix without imputation or reference features. [PDF]
Peng Y +8 more
europepmc +1 more source
SMAD4 is identified as a guardian of 3D genome architecture in lung squamous cell carcinoma. Loss of SMAD4 unleashes EP300 at chromatin loop anchors, strengthening enhancer–promoter looping and H3K27ac at the SOX2 locus to drive aberrant SOX2 activation and tumor cell proliferation.
Qian Tang +33 more
wiley +1 more source
Integrating Hi-C data and RNA-seq data to reveal the 3D genome in sheep. [PDF]
Xu Q +15 more
europepmc +1 more source
Thermally activated LiHCOO induces in situ pseudo‐halide diffusion, promoting buried interface strain release and perovskite crystallization. The monoclinic LiHCOO phase forms an open framework structure that enhances HCOO− diffusion and drives interfacial restructuring.
Chao Gao +4 more
wiley +1 more source
Detecting chromosomal rearrangements in boars using Hi-C. [PDF]
Burden F +5 more
europepmc +1 more source
Resistant Peanut Genotype Reprograms Rhizosphere Metabolism to Enhance Bacterial Wilt Suppression
The resistant peanut genotype selectively recruits beneficial bacteria, which coincides with the activation of salicylic acid (SA)‐dependent systemic acquired resistance (SAR) against Ralstonia solanacearum. Keystone rhizosphere metabolites are positively correlated with both beneficial microbiome assembly and SAR gene expression.
Rui Ren +20 more
wiley +1 more source
Hi-C Links Reveal Viral Activity and Infection Within the Free-Living Microbial Community of a Secondary Chlorophyll Maximum in the Eastern Tropical North Pacific. [PDF]
Rathwell C, Fuchsman CA, Rocap G.
europepmc +1 more source
Mixed‐Polymer Hole Transport Layers Reinforce Au‐Anode Top Emitting Perovskite Light Emitting Diodes
Au‐anode corrosion is shown to occur rapidly under voltage bias in MAPbI3 perovskite LEDs. Resulting Au+ migration quickly leads to device shorting and unstable emission during constant current driving. We demonstrate that using a simple mixed‐polymer hole transport layer containing polyTPD and PVK can reduce Au‐corrosion and stabilize LED operation ...
James C. Loy +5 more
wiley +1 more source
Protocol for the generation of low-input Hi-C sequencing libraries of FACS-isolated mitotic cells. [PDF]
Nichols A +5 more
europepmc +1 more source
The Spatiotemporal Genetic Architecture of Seed Vigor in Upland Cotton
Leveraging the semi‐automated SeedRanger platform, we profiled the germination kinetics of 356 cotton accessions at a 30‐min interval. This high‐throughput phenomic approach delineated a temporal genetic network comprising 541 stage‐specific loci. Crucially, functional validation identified FLA2 as a pivotal, auxin‐modulated regulator that orchestrates
Luyao Wang +32 more
wiley +1 more source

