Results 11 to 20 of about 41,584,039 (265)
HiCeekR: A Novel Shiny App for Hi-C Data Analysis [PDF]
Frontiers in Genetics, 2019 The High-throughput Chromosome Conformation Capture (Hi-C) technique combines the power of the Next Generation Sequencing technologies with chromosome conformation capture approach to study the 3D chromatin organization at the genome-wide scale. Although
Lucio Di Filippo +5 more
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Comparison of normalization methods for Hi-C data [PDF]
BioTechniques, 2020 Hi-C has been predominately used to study the genome-wide interactions of genomes. In Hi-C experiments, it is believed that biases originating from different systematic deviations lead to extraneous variability among raw samples, and affect the ...
Hongqiang Lyu, Erhu Liu, Zhifang Wu
doaj +3 more sources
Visualizing and Annotating Hi-C Data
, 2021 Epigenomics studies require the combined analysis and integration of multiple types of data and annotations to extract biologically relevant information.
Pal K +3 more
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The DLO Hi-C Tool for Digestion-Ligation-Only Hi-C Chromosome Conformation Capture Data Analysis [PDF]
Genes, 2020 It is becoming increasingly important to understand the mechanism of regulatory elements on target genes in long-range genomic distance. 3C (chromosome conformation capture) and its derived methods are now widely applied to investigate three-dimensional (
Hao Jiang +6 more
core +4 more sources
BEKVAEM: INTEGRATIVE DATA EXPLORER FOR HI-C DATA
Journal of Bioinformatics and Genomics, 2019 Motivation: The browser-based visualization of Hi-C contact maps alongside complementary data tracks is a computationally challenging task and requires an efficient software implementation to run on small clients.
Андреас Хофманн +3 more
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Measuring the reproducibility and quality of Hi-C data
Genome Biology, 2019 Background Hi-C is currently the most widely used assay to investigate the 3D organization of the genome and to study its role in gene regulation, DNA replication, and disease.
Galip Gürkan Yardımcı +18 more
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Galaxy HiCExplorer 3: a web server for reproducible Hi-C, capture Hi-C and single-cell Hi-C data analysis, quality control and visualization [PDF]
Nucleic Acids Research, 2020 International audienceThe Galaxy HiCExplorer provides a web service at https://hicexplorer.usegalaxy.eu. It enables the integrative analysis of chromosome conformation by providing tools and computational resources to pre-process, analyse and visualize ...
Manke, Thomas +7 more
core +6 more sources
Loop detection using Hi-C data with HiCExplorer [PDF]
GigaScience, 2022 BACKGROUND: Chromatin loops are an essential factor in the structural organization of the genome; however, their detection in Hi-C interaction matrices is a challenging and compute-intensive task.
Grüning, Björn +2 more
core +4 more sources
Comparison of computational methods for Hi-C data analysis [PDF]
Nature Methods, 2017 Hi-C is a genome-wide sequencing technique used to investigate 3D chromatin conformation inside the nucleus. Computational methods are required to analyze Hi-C data and identify chromatin interactions and topologically associating domains (TADs) from ...
Livi, Carmen Maria +17 more
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Inferring chromosome radial organization from Hi-C data [PDF]
BMC Bioinformatics, 2020 Background The nonrandom radial organization of eukaryotic chromosome territories (CTs) inside the nucleus plays an important role in nuclear functional compartmentalization. Increasingly, chromosome conformation capture (Hi-C) based approaches are being
Priyojit Das +2 more
doaj +4 more sources