Results 61 to 70 of about 39,833,464 (257)
Scool: a new data storage format for single-cell Hi-C data
, 2020 MotivationSingle-cell Hi-C research currently lacks an efficient, easy to use and shareable data storage format. Recent studies have used a variety of sub-optimal solutions: publishing raw data only, text-based interaction matrices, or reusing ...
Grüning, Björn +7 more
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Data for the HAdV55 RNA-seq and Hi-C
, 2023 Analysis data for the RNA-seq and Hi-C about adenovirus and A549 cells ...
Kaiying Wang (14583608)
core +1 more source
Effective normalization for copy number variation in Hi-C data
BMC Bioinformatics, 2018 Background Normalization is essential to ensure accurate analysis and proper interpretation of sequencing data, and chromosome conformation capture data such as Hi-C have particular challenges. Although several methods have been proposed, the most widely
Nicolas Servant +4 more
doaj +1 more source
DeepHiC: A generative adversarial network for enhancing Hi-C data resolution.
PLoS Computational Biology, 2020 Hi-C is commonly used to study three-dimensional genome organization. However, due to the high sequencing cost and technical constraints, the resolution of most Hi-C datasets is coarse, resulting in a loss of information and biological interpretability ...
Hao Hong +14 more
doaj +1 more source
Genomics and Computational Biology, 2017 The detailed analysis of chromatin structure has been enabled due to rapid development of chromosome conformation capture techniques. One of the most popular and widespread variations is high throughput conformation capture, or Hi-C, based on paired-end sequencing.
Aleksey Aleksandrovich Gavrilov +4 more
openaire +1 more source
Rich chromatin structure prediction from Hi-C data [PDF]
IEEE/ACM Transactions on Computational Biology and Bioinformatics, 2015 ABSTRACT Recent studies involving the 3-dimensional conformation of chromatin have revealed the important role it has to play in different processes within the cell. These studies have also led to the discovery of densely interacting segments of the chromosome, called topologically associating domains.
Laraib Malik, Rob Patro
openaire +3 more sources
Computational and Structural Biotechnology Journal, 2023 High-throughput chromatin conformation capture technologies, such as Hi-C and Micro-C, have enabled genome-wide view of chromatin spatial organization.
Jonathan Rosen +6 more
doaj +1 more source
Hi-C data reveals interactions within and among chromosomes.
, 2018 A. Each element of the matrix reflects the frequency of contacts between two genomic windows in an exemplar region of chromosome 3. Repeat density and the locations of AT-rich regions (blue) are plotted below the matrix, as in Fig 2.
Daniel Berry (3482828) +9 more
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Supplement_Material_1 Quality control of Hi-C data
, 2022 Quality control of Hi-C ...
Guofeng Meng (6159248)
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