Predicting the Perceptual Consequences of Hidden Hearing Loss [PDF]
Trends in Hearing, 2016 Recent physiological studies in several rodent species have revealed that permanent damage can occur to the auditory system after exposure to a noise that produces only a temporary shift in absolute thresholds.
Andrew J. Oxenham
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Slight and hidden hearing loss differentially affect short- and long-term memory in young rats. [PDF]
Behav PharmacolMild forms of hearing loss (HL) have been linked to cognitive impairments in children, yet the neurobiological mechanisms underlying this connection remain unclear.
Jagersma JD, Pyott SJ, Olivier JDA.
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From hidden hearing loss to supranormal auditory processing by neurotrophin 3-mediated modulation of inner hair cell synapse density. [PDF]
PLoS BiolLoss of synapses between spiral ganglion neurons and inner hair cells (IHC synaptopathy) leads to an auditory neuropathy called hidden hearing loss (HHL) characterized by normal auditory thresholds but reduced amplitude of sound-evoked auditory ...
Ji L +6 more
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Protection of Cochlear Ribbon Synapses and Prevention of Hidden Hearing Loss [PDF]
Neural Plasticity, 2020 In the auditory system, ribbon synapses are vesicle-associated structures located between inner hair cells (IHCs) and spiral ganglion neurons that are implicated in the modulation of trafficking and fusion of synaptic vesicles at the presynaptic ...
Mei Wei +5 more
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FGF22 deletion causes hidden hearing loss by affecting the function of inner hair cell ribbon synapses. [PDF]
Front Mol Neurosci, 2022 Ribbon synapses are important structures in transmitting auditory signals from the inner hair cells (IHCs) to their corresponding spiral ganglion neurons (SGNs).
Hou S +10 more
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The role of GDF15 in attenuating noise-induced hidden hearing loss by alleviating oxidative stress. [PDF]
Cell Biol ToxicolNoise-induced hidden hearing loss (HHL) is a newly uncovered form of hearing impairment that causes hidden damage to the cochlea. Patients with HHL do not have significant abnormalities in their hearing thresholds, but they experience impaired speech ...
Jiang Y +11 more
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Is allergic rhinitis associated with hidden hearing loss in pediatric/adolescent patients? A cross-sectional study [PDF]
Frontiers in PediatricsIntroductionThis study aims to investigate the potential impact of allergic rhinitis (AR) on auditory function in children/adolescents and whether AR causes hidden hearing loss.MethodsThis cross-sectional study enrolled children/adolescents (12–18 years)
Shang Gao +6 more
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Trk agonist drugs rescue noise-induced hidden hearing loss [PDF]
JCI Insight, 2021 TrkB agonist drugs are shown here to have a significant effect on the regeneration of afferent cochlear synapses after noise-induced synaptopathy. The effects were consistent with regeneration of cochlear synapses that we observed in vitro after synaptic
Katharine A. Fernandez +6 more
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Animal models of hidden hearing loss: Does auditory-nerve-fiber loss cause real-world listening difficulties? [PDF]
Mol Cell Neurosci, 2022 Afferent innervation of the cochlea by the auditory nerve declines during aging and potentially after sound overexposure, producing the common pathology known as cochlear synaptopathy.
Henry KS.
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Iron deficiency at birth and risk of hidden hearing loss in infants modification by socioeconomic status: mother-newborn cohort in Shenyang, China. [PDF]
BMC Public HealthThe diagnosis of hidden hearing loss (HHL) in calm state has not yet been determined, while the nutritional status is not involved in its pathogenic risk factors. In utero iron deficiency (ID) may delay auditory neural maturation in infants. We evaluated
Hao S +7 more
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