Results 71 to 80 of about 747,976 (285)

Large Scale Variational Bayesian Inference for Structured Scale Mixture Models [PDF]

open access: yes, 2012
Natural image statistics exhibit hierarchical dependencies across multiple scales. Representing such prior knowledge in non-factorial latent tree models can boost performance of image denoising, inpainting, deconvolution or reconstruction substantially ...
Ko, Young Jun, Seeger, Matthias
core   +2 more sources

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

One Standard for All: Uniform Scale for Comparing Individuals and Groups in Hierarchical Bayesian Evidence Accumulation Modeling

open access: yesJournal of Cognition
In recent years, a growing body of research uses Evidence Accumulation Models (EAMs) to study individual differences and group effects. This endeavor is challenging because fitting EAMs requires constraining one of the EAM parameters to be equal for all ...
Rotem Berkovich, Nachshon Meiran
doaj   +1 more source

Malaria parasite clearance rate regression: an R software package for a Bayesian hierarchical regression model

open access: yesMalaria Journal, 2019
Background Emerging resistance to anti-malarial drugs has led malaria researchers to investigate what covariates (parasite and host factors) are associated with resistance.
Saeed Sharifi-Malvajerdi   +7 more
doaj   +1 more source

Why human connection is the true metric of research success

open access: yesFEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan   +3 more
wiley   +1 more source

Optimal shrinkage estimation in heteroscedastic hierarchical linear models

open access: yes, 2015
Shrinkage estimators have profound impacts in statistics and in scientific and engineering applications. In this article, we consider shrinkage estimation in the presence of linear predictors.
Kou, Samuel, Yang, Justin J.
core  

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

open access: yesFEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin   +3 more
wiley   +1 more source

Personalized medicine enrichment design for DHA supplementation clinical trial

open access: yesContemporary Clinical Trials Communications, 2017
Personalized medicine aims to match patient subpopulation to the most beneficial treatment. The purpose of this study is to design a prospective clinical trial in which we hope to achieve the highest level of confirmation in identifying and making ...
Yang Lei   +3 more
doaj   +1 more source

Partitioned conditional generalized linear models for categorical data [PDF]

open access: yes, 2014
In categorical data analysis, several regression models have been proposed for hierarchically-structured response variables, e.g. the nested logit model. But they have been formally defined for only two or three levels in the hierarchy.
Guédon, Yann   +2 more
core   +4 more sources

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

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