Results 81 to 90 of about 747,976 (285)

Combining Methods in Supervised Classification: a Comparative Study on Discrete and Continuous Problems

Revstat Statistical Journal, 2006
Often in discriminant analysis several models are estimated but based on some validation criterion, a single model is selected. In the purpose of taking profit from several potential models, classification rules combining models are considered in this ...
Isabel Brito , Gilles Celeux , Ana Sousa Ferreira   +2 more
doaj   +1 more source

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

The Best Fit Bayesian Hierarchical Generalized Linear Model Selection Using Information Complexity Criteria in the MCMC Approach

Journal of Mathematics
Both frequentist and Bayesian statistics schools have improved statistical tools and model choices for the collected data or measurements. Model selection approaches have advanced due to the difficulty of comparing complicated hierarchical models in ...
Endris Assen Ebrahim, Mehmet Ali Cengiz, Erol Terzi   +2 more
doaj   +1 more source

Impact of communities, health, and emotional-related factors on smoking use: comparison of joint modeling of mean and dispersion and Bayes’ hierarchical models on add health survey

BMC Medical Research Methodology, 2017
Background The analysis of correlated binary data is commonly addressed through the use of conditional models with random effects included in the systematic component as opposed to generalized estimating equations (GEE) models that addressed the random ...
Jie Pu, Di Fang, Jeffrey R. Wilson
doaj   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

Hierarchical Bayesian models for the estimation of unemployment rates in small domains of the italian labour force survey

Statistica, 2007
In this paper we introduce shrinkage estimators for the estimation of the Unemployment rate in small domains of the Italian Labour Force Survey. The proposed estimators are based on Hierarchical Linear Mixed Models and on the borrowing strength on both ...
Enrico Fabrizi
doaj   +1 more source

Whole‐Body Pattern of Muscle Degeneration and Progression in Sarcoglycanopathies

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To characterize whole‐body intramuscular fat distribution pattern in patients with sarcoglycanopathies and explore correlations with disease severity, duration and age at onset. Methods Retrospective, cross‐sectional, multicentric study enrolling patients with variants in one of the four sarcoglycan genes who underwent whole‐body ...
Laura Costa‐Comellas, Mauro Monforte, Angel Sanchez‐Montañez, Penélope Romero‐Duque, Elena Pegoraro, Jordi Díaz‐Manera, Dmitry Vlodavets, Lorenzo Maggi, Marco Moscatelli, Adele D‘Amico, Montse Olivé, Jorge Alonso‐Pérez, Giacomo Comi, José Miguel Escudero‐Fernández, Gabriela S. Urcuyo, Anna Pichiecchio, Angela Berardinelli, Kristl G. Claeys, Claudio Bruno, Chiara Panicucci, Sara Bortolani, Eleonora Torchia, Enzo Ricci, Soledad Monges, Jorge A. Bevilacqua, Jorge Diaz‐Jara, Maggie C. Walter, Simone Thiele, Nicoline Løkken, John Vissing, Susana Quijano‐Roy, Robert Y. Carlier, Nicol C. Voermans, Chiara Marini‐Bettolo, Michela Guglieri, Volker Straub, Lea Leonardis, Francina Munell, David Gómez‐Andrés, Giorgio Tasca   +39 more
wiley   +1 more source

Unraveling the Molecular Mechanisms of Glioma Recurrence: A Study Integrating Single‐Cell and Spatial Transcriptomics

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Glioma recurrence severely impacts patient prognosis, with current treatments showing limited efficacy. Traditional methods struggle to analyze recurrence mechanisms due to challenges in assessing tumor heterogeneity, spatial dynamics, and gene networks.
Lei Qiu, Yinjiao Fei, Jiaxuan Ding, Kexin Shi, Jinyan Luo, Yuchen Zhu, Xingjian Sun, Gefei Jiang, Yuandong Cao, Weilin Xu, Shu Zhou   +10 more
wiley   +1 more source

A Framework to Interpret Nonstandard Log-Linear Models

Austrian Journal of Statistics, 2016
The formulation of log-linear models within the framework of Generalized Linear Models offers new possibilities in modeling categorical data. The resulting models are not restricted to the analysis of contingency tables in terms of ordinary hierarchical ...
Patrick Mair
doaj   +1 more source

Hierarchical Models, Marginal Polytopes, and Linear Codes

Kybernetika, 2008
In this paper, we explore a connection between binary hierarchical models, their marginal polytopes and codeword polytopes, the convex hulls of linear codes. The class of linear codes that are realizable by hierarchical models is determined. We classify all full dimensional polytopes with the property that their vertices form a linear code and give an ...
Thomas Kahle, Walter Wenzel, Nihat Ay
openaire   +4 more sources