Results 61 to 70 of about 1,044,365 (214)

Normal Binary Hierarchical Models

, 2016
Each simplicial complex and integer vector yields a vector configuration whose combinatorial properties are important for the analysis of contingency tables.
Bernstein, Daniel Irving, Sullivant, Seth   +1 more
core   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source

Key Habitat and Predatory Influences on the Community- and Species-Level Population Dynamics of Spring-Breeding Amphibian Larvae Within a Remnant Tupelo-Cypress Wetland

Hydrobiology
Understanding the factors influencing amphibian populations is essential for effective freshwater conservation, particularly for species with biphasic life histories.
Jacob M. Hutton, Robin W. Warne
doaj   +1 more source

A class of admissible estimators of multiple regression coefficient with an unknown variance

Statistical Theory and Related Fields, 2020
Suppose that we observe ${\boldsymbol y} \mid {\boldsymbol \theta },\ \tau \sim N_p({\boldsymbol X}{\boldsymbol \theta },\tau ^{-1}{\boldsymbol I}_p) $, where ${\boldsymbol \theta } $ is an unknown vector with unknown precision τ.
Chengyuan Song, Dongchu Sun
doaj   +1 more source

Large positive ecological changes of small urban greening actions

Ecological Solutions and Evidence, 2023
The detrimental effects of environmental change on human and non‐human diversity are acutely manifested in urban environments. While urban greenspaces are known to mitigate these effects and support functionally diverse ecological communities, evidence ...
Luis Mata, Amy K. Hahs, Estibaliz Palma, Anna Backstrom, Nikolas Johnston, Tyler King, Ashley R. Olson, Christina Renowden, Tessa R. Smith, Blythe Vogel, Samantha Ward   +10 more
doaj   +1 more source

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

Molecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath, Irene A. George, Srikanth S. Manda, Prasanth Ariyannur, Ekta R. Dhawale, Raja Sekhar Kommu, Rajan Datar, Darshana Patil, Vinita Trivedi, Manisha Singh, Kumar Prabhash, Sewanti Limaye, Richa Chauhan, Prashant Kumar   +13 more
wiley   +1 more source

A New Zero-Inflated Negative Binomial Multilevel Model for Forecasting the Demand of Disaster Relief Supplies in the State of Sao Paulo, Brazil

Mathematics, 2022
This article presents the results of the implementation of a forecasting model, to predict the relief materials needed for assisting in decisions prior to natural disasters, thus filling a gap in the exploration of Generalized Linear Mixed Models (GLMM ...
Camila Pareja Yale, Hugo Tsugunobu Yoshida Yoshizaki, Luiz Paulo Fávero   +2 more
doaj   +1 more source

Scaling Laws in Hierarchical Clustering Models with Poisson Superposition

, 1994
Properties of cumulant- and combinant ratios are studied for multihadron final states composed of Poisson distributed clusters. The application of these quantities to ``detect'' clusters is discussed.
Carruthers, Carruthers, Carruthers, Carruthers, de Deus, de Deus, De Wolf, Dokshitzer, Eggers, Feller, Fry, Fry, Giovannini, Giovannini, Groth, Gyulassy, Hegyi, Hegyi, Hegyi, Hegyi, Kauffmann, Le Bellac, Lupia, Mandelbrot, Meiksin, Peebles, Peebles, Peschanski, S. Hegyi, Szapudi, Szapudi, Ugoccioni, Van Hove, Van Hove, White   +34 more
core   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

The environmental dependence of clustering in hierarchical models

, 2005
In hierarchical models, density fluctuations on different scales are correlated. This induces correlations between dark halo masses, their formation histories, and their larger-scale environments.
Balogh, Balogh, Balogh, Benson, Blanton, Cole, Cooray, Dressler, Farouki, Gao, Gomez, Gunn, Hogg, Kaiser, Kauffmann, Kauffmann, Kauffmann, Kravtsov, Lacey, Lemson, Mo, Mo, Moore, Navarro, Peebles, Peebles, Press, Ravi K. Sheth, Sheth, Sheth, Sheth, Sheth, Sheth, Sheth, Sheth, Sheth, Sheth, Sheth, Somerville, Ummi Abbas, White, White, Yang, Zehavi   +43 more
core   +1 more source