HIF-1α attenuates ferroptosis-associated dermal fibroblast senescence via modulation of NF-κB-DPP4 signaling. [PDF]
Ng SC +8 more
europepmc +1 more source
Kuanxiong aerosol protects against coronary microvascular dysfunction through improving angiogenesis via HIF-1α-ITGAX axis. [PDF]
Jiang Y +10 more
europepmc +1 more source
HIF-1α as a Central Regulator of Monocyte Responses to Hypoxia. [PDF]
Lampiasi N, Russo R.
europepmc +1 more source
BCAT1-dependent HIF-1α stabilization is a targetable metabolic vulnerability in hepatocellular carcinoma. [PDF]
Zhang MS +28 more
europepmc +1 more source
ADSC-Derived CCL8 Regulates HIF-1α Signaling and Promotes Colorectal Cancer Progression in a 3D Coculture Platform. [PDF]
Yun JE +7 more
europepmc +1 more source
HIF-1-dependent transcriptional activity is required for oxygen-mediated HIF-1α degradation [PDF]
Hypoxia-inducible factor-1α (HIF-1α) plays a central role in oxygen homeostasis. In normoxia, HIF-1α is a short lived protein, whereas hypoxia rapidly increases HIF-1α protein levels by relaxing its ubiquitin–proteasome-dependent degradation.
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