Results 1 to 10 of about 126,064 (119)
Hypoxia-Inducible Factor 1 and Mitochondria: An Intimate Connection
Biomolecules, 2022 The general objective of the review is to explain the interaction between HIF-1 and mitochondria. On the one hand, this review describes the effects of HIF-1 on mitochondrial structure, including quantity, distribution, and morphology, as well as on ...
Xiaochen Huang, Li Zhao, Ruiyun Peng
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Intestinal HIF-2α Regulates GLP-1 Secretion via Lipid Sensing in L-CellsSummary
Cellular and Molecular Gastroenterology and Hepatology, 2022 Background & Aims: Compelling evidence shows that glucagon-like peptide-1 (GLP-1) has a profound effect in restoring normoglycemia in type 2 diabetic patients by increasing pancreatic insulin secretion.
Raja Gopal Reddy Mooli +8 more
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MicroRNA-122-5p ameliorates tubular injury in diabetic nephropathy via FIH-1/HIF-1α pathway
Renal Failure, 2022 Diabetes kidney disease (DKD) affects approximately one-third of diabetes patients, however, the specific molecular mechanism of DKD remains unclear, and there is still a lack of effective therapies.
Li Cheng, Xinying Qiu, Liyu He, Li Liu
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Metals, 2022 Lithium-ion batteries (LIBs) are an important pillar for the sustainable transition of the mobility and energy storage sector. LIBs are complex devices for which waste management must incorporate different recycling technologies to produce high-quality ...
Denis Manuel Werner +2 more
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Influence of Pretreatment Strategy on the Crushing of Spent Lithium-Ion Batteries
Metals, 2022 The rising production of lithium-ion batteries (LIBs) due to the introduction of electric mobility as well as stationary energy storage devices demands an efficient and sustainable waste management scheme for legislative, economic and ecologic reasons ...
Denis Manuel Werner +2 more
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Biomedicines, 2020 Oxygen (O2) is essential for human life. Molecular oxygen is vital for the production of adenosine triphosphate (ATP) in human cells. O2 deficiency leads to a reduction in the energy levels that are required to maintain biological functions.
Kiichi Hirota
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Effect of exercise on HIF-1 and VEGF signaling
Journal of Physical Fitness and Sports Medicine, 2012 This review summarizes the literature describing the significance of various conditions, such as hypoxia, oxidative stress, and, above all, physical exercise, in the hypoxia-inducible factor-1 (HIF-1) and vascular endothelial growth factor (VEGF ...
Hideki Ohno +8 more
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Hypoxia and HIFs in Ewing sarcoma: new perspectives on a multi-facetted relationship
Molecular Cancer, 2023 Hypoxia develops during the growth of solid tumors and influences tumoral activity in multiple ways. Low oxygen tension is also present in the bone microenvironment where Ewing sarcoma (EwS) – a highly aggressive pediatric cancer – mainly arises. Hypoxia
A. Katharina Ceranski +5 more
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Hipoksiyle İndüklenen Faktör-1: Hücrenin Hipoksiye Fizyolojik ve Patolojik Cevabı
Sakarya Tıp Dergisi, 2014 Oksijen homeostazında kritik bir rol oynayan hipoksiyle indüklenen faktör-1 (HIF-1); anjiyogenezis, eritropoezis, demir metabolizması ve glukoz metabolizması gibi metabolik süreçlerin transkripsiyonel regülatörüdür.
Saygın Hasan Demirel +1 more
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Hypoxia-induced chemoresistance in cancer cells: The role of not only HIF-1
Biomedical Papers, 2015 Background: The aim of this review is to provide the information about molecular basis of hypoxia-induced chemoresistance, focusing on the possibility of diagnostic and therapeutic use.
Helena Doktorova +3 more
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