Results 191 to 200 of about 126,163 (218)

Circadian gene BMAL1 ameliorates renal ischaemia-reperfusion injury in diabetic mice by enhancing mitophagy via the HIF-1/BNIP3 pathway. [PDF]

Sci Rep
Deng X, Leng Y, Xiong Y, Li W, Chen W, Yang Y, Wang B, Gong S, Wang Y, Yang B, Li W.   +10 more
europepmc   +1 more source

Rhaponticin Blocks Glycolysis‐Mediated Histone Lactylation to Suppress Tongue Squamous Cell Carcinoma via HIF‐1α Activity Inhibition

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Tongue squamous cell carcinoma (TSCC) often develops therapeutic resistance. Metabolic reprogramming, particularly the glycolysis/lactate/histone lactylation axis, is a critical driver of tumor progression and therapy resistance. This study investigated the anti‐tumor mechanism of Rhaponticin (Rha), focusing on the metabolic/epigenetic axis ...
Yuan Wu, Liang‐Liang Yao, Lin Jiang, Zhi‐Yi Fang, Jia‐Jun Zhu, Yi‐Sen Shao, Wen‐Juan Wang, Xiao‐Wen Wan   +7 more
wiley   +1 more source

Early plasma changes of HIF-1 alpha, matrix metalloproteinases-2 and - 9, and tissue inhibitor of matrix metalloproteinase-1 in patients with infantile hemangiomas treated with propranolol. [PDF]

Pharmacol Rep
Kowalska M, Koper-Lenkiewicz OM, Kamińska J, Dębek W, Hermanowicz A, Matuszczak E.   +5 more
europepmc   +1 more source

mRNA Vaccination for COVID-19 Lowers the Risk for Pulmonary Fibrosis Through GIP-10/Gal-3/HIF-1 Downregulation. [PDF]

Cureus
Al-Sammarraie MR, Azaiez FD, Litaiem H.
europepmc   +1 more source

A dynamic model of gene activation in response to hypoxia accounting for both HIF-1 and HIF-2. [PDF]

Brief Funct Genomics
Cabaj A, Charzyńska A, Moszyńska A, Jaśkiewicz M, Bartoszewski R, Dąbrowski M.   +5 more
europepmc   +1 more source

Carbonic anhydrase IX downregulation linked to disruption of HIF-1, NFκB and STAT3 pathways as a new mechanism of ibuprofen anti-cancer effect. [PDF]

PLoS One
Grossmannova K, Belvoncikova P, Puzderova B, Simko V, Csaderova L, Pastorek J, Barathova M.   +6 more
europepmc   +1 more source

CaMKIIγ advances chronic intermittent hypoxia-induced cardiomyocyte apoptosis via HIF-1 signaling pathway. [PDF]

Sleep Breath
Yang X, Sha X, Wang G, Xu D, Zhang J, Tang M, Shi J.   +6 more
europepmc   +1 more source

Correction to: A dynamic model of gene activation in response to hypoxia accounting for both HIF-1 and HIF-2. [PDF]

Brief Funct Genomics
europepmc   +1 more source

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Revisiting the HIF switch in the tumor and its immune microenvironment

Trends in Cancer, 2022
Mei Yee Koh
exaly  

Hif-1a suppresses ROS-induced proliferation of cardiac fibroblasts following myocardial infarction

Cell Stem Cell, 2022
Vaibhao Janbandhu, Vikram Tallapragada, Ralph Patrick   +2 more
exaly