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Long-term abuse of a high-carbohydrate diet is as harmful as a high-fat diet for development and progression of liver injury in a mouse model of NAFLD/NASH.

Nutrition (Burbank, Los Angeles County, Calif.), 2020
OBJECTIVES Non-alcoholic fatty liver disease (NAFLD) has become the most common liver disease globally. It is caused by a complex network of factors, including diet.
S. Pompili   +8 more
semanticscholar   +1 more source

Gemfibrozil improves lipid metabolism in Nile tilapia Oreochromis niloticus fed a high-carbohydrate diet through peroxisome proliferator activated receptor-α activation.

General and Comparative Endocrinology, 2020
High carbohydrate diet (HCD) can induce lipid metabolism disorder, characterized by excessive lipid in farmed fish. Peroxisome proliferator activated receptor-α (PPARα) plays an important role in lipid homeostasis.
Yuan Luo   +6 more
semanticscholar   +1 more source

Effect of Calorie-Unrestricted Low-Carbohydrate, High-Fat Diet Versus High-Carbohydrate, Low-Fat Diet on Type 2 Diabetes and Nonalcoholic Fatty Liver Disease

Annals of Internal Medicine, 2022
BACKGROUND It remains unclear if a low-carbohydrate, high-fat (LCHF) diet is a possible treatment strategy for type 2 diabetes mellitus (T2DM), and the effect on nonalcoholic fatty liver disease (NAFLD) has not been investigated.
C. D. Hansen   +22 more
semanticscholar   +1 more source

Responses of glycolysis, glycogen accumulation and glucose-induced lipogenesis in grass carp and Chinese longsnout catfish fed high-carbohydrate diet

, 2020
This study investigated the different adaptive metabolic strategies of grass carp (Ctenopharyngodon idellus) and Chinese longsnout catfish (Leiocassis longirostris Gunther) to a high-carbohydrate diet (HCD).
Jingzhi Su   +9 more
semanticscholar   +1 more source

Low versus high carbohydrate diet in type 1 diabetes: A 12‐week randomized open‐label crossover study

Diabetes, obesity and metabolism, 2019
To compare the effects of a low carbohydrate diet (LCD  250 g carbohydrate/d) on glycaemic control and cardiovascular risk factors in adults with type 1 diabetes.
S. Schmidt   +8 more
semanticscholar   +1 more source

High carbohydrate diets and Alzheimer's disease

Medical Hypotheses, 2004
Alzheimer's disease (AD) is a common, progressive, neurodegenerative disease that primarily afflicts the elderly. A well-defined risk factor for late onset AD is possession of one or more alleles of the epsilon-4 variant (E4) of the apolipoprotein E gene.
openaire   +2 more sources

Hypolipidemic effects of high-carbohydrate, high-fiber diets

Metabolism, 1980
Abstract Serial measurements of serum cholesterol and triglyceride (TG) concentrations were performed in diabetic men fed high-carbohydrate, high-fiber (HCF) as well as high-carbohydrate, low-fiber (HCLF) diets. Fourteen lean men were first fed control diets for 1 wk and then fed weight-maintaining HCF diets (70% carbohydrate) that were restricted in ...
J W, Anderson, W J, Chen, B, Sieling
openaire   +2 more sources

Low-fat, High-carbohydrate Diets and Atherogenic Risk

Nutrition Reviews, 2009
The debate surrounding the use of low-fat, high-carbohydrate diets has raised concerns regarding the atherogenicity of triglyceride-rich lipoproteins. A recent study has demonstrated that feeding a diet high in carbohydrate delays very low-density lipoprotein (VLDL) clearance.
C L, Baum, M, Brown
openaire   +2 more sources

Diet and HDL Metabolism: High Carbohydrate vs. High Fat Diets

1987
An increased level of plasma low density lipoproteins (LDL) is a major risk factor in the development of coronary artery disease (1). Conversely, plasma high density lipoproteins (HDL) and apolipoprotein A-I, the major protein constituent of HDL, are inversely related to the disease (2-4).
R L, Jackson   +3 more
openaire   +2 more sources

Diabetic diets: high carbohydrate combined with high fiber

The American Journal of Clinical Nutrition, 1980
The ideal level of carbohydrate intake for diabetics placed on high-fiber diets is unknown. Nineteen diabetics, therefore, took part in a total of twenty-four 5-day studies of fiber supplementation (guar) with carbohydrate intakes ranging from 22 to 61% of total calories.
D J, Jenkins   +7 more
openaire   +2 more sources

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