Introduction Obesity is one of the most burdensome health problems and is closely linked to leptin resistance. The study examined whether an alternate-day high-fat diet (ADF) and/or GLP-1 agonist (exenatide) modulate brain leptin resistance caused by a ...
Mona K. Tawfik +4 more
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Effect of Tocotrienols Derived from Annatto on Lipid Profile and Some Adipokine Hormones in Rats Fed a High-Fat Diet [PDF]
Obesity is a metabolic condition that causes people to develop a variety of diseases and has emerged as a serious global public-health problem. Tocotrienol, a member of the vitamin E family that comes from the annatto bean (Bixa orellana), is special in ...
Eman Rahi, Nameer Khudhair
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Caspase-1 as a central regulator of high fat diet-induced non-alcoholic steatohepatitis. [PDF]
Nonalcoholic steatohepatitis (NASH) is associated with caspase activation. However, a role for pro-inflammatory caspases or inflammasomes has not been explored in diet-induced liver injury.
Laura J Dixon +4 more
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The Effect of Exercise on Serum Resistin and Leptin Values in Rats Fed with a High Fat Diet
Aim: This study was performed to investigate the effect of exercise on serum resistin and leptin values in rats fed with a high-fat diet. Material and Method: 24 Wistar albino male rats were used in the study.
Nizamettin Günbatar, Bahattin Bulduk
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Body fat accumulation in zebrafish is induced by a diet rich in fat and reduced by supplementation with green tea extract. [PDF]
Fat-rich diets not only induce obesity in humans but also make animals obese. Therefore, animals that accumulate body fat in response to a high-fat diet (especially rodents) are commonly used in obesity research.
Shinichi Meguro +2 more
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High-intensity interval training ameliorates high-fat diet-induced elevation of aminotransferases in male Wistar rats [PDF]
Background and aims: A high-fat diet increases triglyceride (TG) accumulations in hepatocytes and results in non-alcoholic fatty liver diseases (NAFLDs). In this regard, this study investigated the effect of high-intensity interval training (HIIT), along
Qazaleh Asqari +3 more
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Excessive dietary fat intake has extensive impacts on several physiological systems and can lead to metabolic and nonmetabolic disease. In animal models of ingestion, exposure to a high fat diet during pregnancy predisposes offspring to increase intake ...
Kinning Poon
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Metabolomic study of the LDL receptor null mouse fed a high-fat diet reveals profound perturbations in choline metabolism that are shared with ApoE null mice [PDF]
Failure to express or expression of dysfunctional low-density lipoprotein receptors (LDLR) causes familial hypercholesterolemia in humans, a disease characterized by elevated blood cholesterol concentrations, xanthomas, and coronary heart disease ...
Benson, G. Martin +5 more
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Failure of a dietary model to affect markers of inflammation in domestic cats [PDF]
Background: Oxidative stress and inflammation can be altered by dietary factors in various species. However, little data are available in true carnivorous species such as domestic cats.
Cox, Eric +6 more
core +6 more sources
Rats Fed Diets with Different Energy Contribution from Fat Do Not Differ in Adiposity
Objective: To determine whether rats reaching the same body mass, having been fed either a low-fat (LFD) or a high-fat diet (HFD), differ in white adipose tissue (WAT) deposition.
Alexander D. Miras +7 more
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