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When is a high fat diet not a high fat diet? [PDF]
Nutrition & Metabolism, 2005 The observation that a high fat/low carbohydrate (CHO) diet has a beneficial effect on a mouse model of Alzheimer's disease (AD) published today is notable given previous results showing that high fat diets have a deleterious effect on AD. Van de Auwera, et al. [1] reported that mice fed a ketogenic diet (
Feinman Richard D
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High fat diet causes rebound weight gain [PDF]
Molecular Metabolism, 2013 Obesity is at epidemic proportions but treatment options remain limited. Treatment of obesity by calorie restriction (CR) despite having initial success often fails due to rebound weight gain. One possibility is that this reflects an increased body weight (BW) set-point.
McNay, David E. G., Speakman, John R.
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Archives of Medical Science, 2023 Introduction Obesity is one of the most burdensome health problems and is closely linked to leptin resistance. The study examined whether an alternate-day high-fat diet (ADF) and/or GLP-1 agonist (exenatide) modulate brain leptin resistance caused by a ...
Mona K. Tawfik +4 more
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Effect of Tocotrienols Derived from Annatto on Lipid Profile and Some Adipokine Hormones in Rats Fed a High-Fat Diet [PDF]
Basrah Journal of Veterinary Research, 2023 Obesity is a metabolic condition that causes people to develop a variety of diseases and has emerged as a serious global public-health problem. Tocotrienol, a member of the vitamin E family that comes from the annatto bean (Bixa orellana), is special in ...
Eman Rahi, Nameer Khudhair
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High-Fat Diet and Female Fertility [PDF]
Endocrinology, 2017 The prevalence of obesity is high among reproductive-age women and is associated with impaired reproductive function. Obesity is multifactorial in origin, yet many cases of obesity result from overconsumption of a diet high in fat. Excess dietary fat increases both adipose and nonadipose tissue lipid content and, through lipotoxicity, leads to cell ...
Natalie M, Hohos +1 more
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High fat diet induced diabetic cardiomyopathy [PDF]
Prostaglandins, Leukotrienes and Essential Fatty Acids (PLEFA), 2011 In response to a chronic high plasma concentration of long-chain fatty acids (FAs), the heart is forced to increase the uptake of FA at the cost of glucose. This switch in metabolic substrate uptake is accompanied by an increased presence of the FA transporter CD36 at the cardiac plasma membrane and over time results in the development of cardiac ...
Dirkx, Ellen +4 more
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Caspase-1 as a central regulator of high fat diet-induced non-alcoholic steatohepatitis. [PDF]
PLoS ONE, 2013 Nonalcoholic steatohepatitis (NASH) is associated with caspase activation. However, a role for pro-inflammatory caspases or inflammasomes has not been explored in diet-induced liver injury.
Laura J Dixon +4 more
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The Effect of Exercise on Serum Resistin and Leptin Values in Rats Fed with a High Fat Diet
Journal of Contemporary Medicine, 2023 Aim: This study was performed to investigate the effect of exercise on serum resistin and leptin values in rats fed with a high-fat diet. Material and Method: 24 Wistar albino male rats were used in the study.
Nizamettin Günbatar, Bahattin Bulduk
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Body fat accumulation in zebrafish is induced by a diet rich in fat and reduced by supplementation with green tea extract. [PDF]
PLoS ONE, 2015 Fat-rich diets not only induce obesity in humans but also make animals obese. Therefore, animals that accumulate body fat in response to a high-fat diet (especially rodents) are commonly used in obesity research.
Shinichi Meguro +2 more
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High-Fat Diet–Induced Retinal Dysfunction [PDF]
Investigative Opthalmology & Visual Science, 2015 The purpose of this study was to investigate the impact of obesity-induced prediabetes/early diabetes on the retina to provide new evidence on the pathogenesis of type 2 diabetes-associated diabetic retinopathy (DR).A high-fat diet (HFD)-induced obesity mouse model (male C57BL/6J) was used in this study.
Richard Cheng-An, Chang +6 more
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