Results 31 to 40 of about 896,517 (311)

Metabolic effects of a high-fat diet post-weaning after low maternal dietary folate during pregnancy and lactation [PDF]

, 2014
Scope Investigate the influence of low-folate supply during pregnancy and lactation on obesity and markers of the metabolic syndrome in offspring, and how provision of a high-fat diet post weaning may exacerbate the resultant phenotype.
Ford, Dianne, Langie, Sabine, Manus, Caroline, Mathers, John C., Maxwell, Ross, McKay, Jill, Xie, Long   +6 more
core   +1 more source

Effects of Excess Energy Intake on Glucose and Lipid Metabolism in C57BL/6 Mice. [PDF]

PLoS ONE, 2016
Excess energy intake correlates with the development of metabolic disorders. However, different energy-dense foods have different effects on metabolism.
Jing Pang, Chao Xi, Xiuqing Huang, Ju Cui, Huan Gong, Tiemei Zhang   +5 more
doaj   +1 more source

High-Fructose/High-Fat Diet Downregulates the Hepatic Mitochondrial Oxidative Phosphorylation Pathway in Mice Compared with High-Fat Diet Alone

Cells, 2022
Both high-fat diet (HFD) alone and high-fructose plus HFD (HFr/HFD) cause diet-induced non-alcoholic fatty liver disease in murine models. However, the mechanisms underlying their impacts on inducing different levels of liver injury are yet to be ...
Milton D. Chiang Morales, Chao-Yuan Chang, Van Long Le, I-Tao Huang, I-Lin Tsai, Hung-Jen Shih, Chun-Jen Huang   +6 more
doaj   +1 more source

A high fat diet fosters elevated bisretinoids

Journal of Biological Chemistry, 2023
High dietary fat intake is associated with metabolic dysregulation, but little is known regarding the effects of a high fat diet (HFD) on photoreceptor cell functioning. We explored the intersection of an HFD and the visual cycle adducts that form in photoreceptor cells by nonenzymatic reactions.
Kim, Hye Jin, Zhao, Jin, Walewski, Jose L., Sparrow, Janet R.   +3 more
openaire   +2 more sources

Vitamin D3 supplementation of a high fat high sugar diet ameliorates prediabetic phenotype in female LDLR–/–and LDLR+/+mice [PDF]

, 2017
© 2017 The Authors. Immunity, Inflammation and Disease Published by John Wiley & Sons Ltd. INTRODUCTION: Fatty liver disease is prevalent in populations with high caloric intake.
Asai, Baldock, Bieghs, Bora, Cani, Chan, Chawla, Del Ben, DeLuca, Dongiovanni, Drewnowski, George, Giugliano, Glaros, Hummasti, Iwaki, Jorde, Jump, Kalra, Karbowska, Kennedy, Kheder, Kitson, Kleiner, Kraakman, Lira, Livak, Lytle, Machado, Madar, Marcotorchino, Merat, Minto, Oh, Okamoto, Parekh, Pham, Roth, Saraswathi, Schwen, Sergeev, Shu, Subramanian, Teramoto, Tintut, Vanlint, Wortsman, Wouters, Yin, Zhang, Zhang   +50 more
core   +1 more source

Beneficial effects of an alternating high- fat dietary regimen on systemic insulin resistance, hepatic and renal inflammation and renal function.

PLoS ONE, 2012
BackgroundAn Alternating high- cholesterol dietary regimen has proven to be beneficial when compared to daily high- cholesterol feeding. In the current study we explored whether the same strategy is applicable to a high- fat dietary regimen.ObjectiveTo ...
Gopala K Yakala, Roel van der Heijden, Grietje Molema, Martin Schipper, Peter Y Wielinga, Robert Kleemann, Teake Kooistra, Peter Heeringa   +7 more
doaj   +1 more source

In vitro study of dietary factors affecting the biohydrogenation shift from trans-11 to trans-10 fatty acids in the rumen of dairy cows [PDF]

, 2012
On the basis of the isomer-specific effects of trans fatty acids (FA) on human health, and the detrimental effect of t10,c12-conjugated linoleic acid (CLA) on cows’ milk fat production, there is a need to identify factors that affect the shift from trans-
Enjalbert, Francis, Nicot, Marie-Claude, Troegeler-Meynadier, Annabelle, Zened, Asma   +3 more
core   +2 more sources

Dietary-induced hypertrophic–hyperplastic obesity in mice

Journal of Lipid Research, 1974
Metabolically intact NMRI mice and genetically obese NZO mice were fed ad lib. either a high-carbohydrate diet (standard) or a high-fat diet for a period of about 11 (NMRI mice) or 38 (NZO mice) wk.
L. Herberg, W. Döppen, E. Major, F.A. Gries   +3 more
doaj   +1 more source

The effects of diet and streptozotocin on metabolism and gut microbiota in a type 2 diabetes mellitus mouse model

Food and Agricultural Immunology, 2020
Diabetes mellitus is a metabolic disorder disease. Diabetes models can be established using diet and/or chemical agents. However, the effects of these methods on the intestinal microbiota are poorly understood. In this study, C57BL/6 mice were fed with a
Ruiyang Yin, Yong Xue, Jinrong Hu, Xiaosong Hu, Qun Shen   +4 more
doaj   +1 more source

High‐Fat‐Diet Intake Enhances Cerebral Amyloid Angiopathy and Cognitive Impairment in a Mouse Model of Alzheimer's Disease, Independently of Metabolic Disorders

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2016
BackgroundThe high‐fat Western diet is postulated to be associated with the onset and progression of Alzheimer's disease (AD). However, the role of high‐fat‐diet consumption in AD pathology is unknown.
Bowen Lin, Yu Hasegawa, Koki Takane, Nobutaka Koibuchi, Cheng Cao, Shokei Kim‐Mitsuyama   +5 more
doaj   +1 more source