Results 161 to 170 of about 10,771 (216)

High-Grade Prostatic Intraepithelial Neoplasia

Reviews in urology, 2011
Prostatic intraepithelial neoplasia (PIN) is considered a precursor lesion to prostate carcinoma and a surrogate marker for cancer in prostate biopsies. It is characterized by secretory epithelial proliferation within the prostate glands and acini that display significant cytological atypia. PIN does not result in an abnormal digital rectal examination
Rajal B. Shah, Ming Zhou
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Epidemiology of High-Grade Prostatic Intraepithelial Neoplasia

Scandinavian Journal of Urology and Nephrology, 2000
This review summarizes published data dealing with the prevalence of high-grade prostatic intraepithelial neoplasia (HGPIN) in a variety of prostate tissue samples. Additionally, we have attempted to document the relationship between HGPIN and the pathological parameters of prostate cancer in autopsy and radical prostatectomy specimens.
W A, Sakr, A, Billis, P, Ekman, T, Wilt, D G, Bostwick   +4 more
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Foamy Gland High-Grade Prostatic Intraepithelial Neoplasia

The American Journal of Surgical Pathology, 2000
A 60-year-old man underwent radical prostatectomy for biopsy-proved adenocarcinoma of the prostate. Histologic examination of the entirely embedded prostatectomy specimen revealed extensive ordinary adenocarcinoma, Gleason's grade 3 + 3 = 6, involving both sides of the gland, and extending into extraprostatic soft tissue at the left base.
D M, Berman, J, Yang, J I, Epstein
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Epidemology of High Grade Prostatic Intraepithelial Neoplasia

Pathology - Research and Practice, 1995
The prevalence of high grade prostatic intraepithelial neoplasia (HGPIN), the age at which this lesion starts and the potential racial or ethnic differences in its distribution are poorly documented. HGPIN is becoming increasingly implicated as a premalignant lesion for clinically significant prostatic carcinoma (PCa) with mounting evidence linking it ...
W A, Sakr, D J, Grignon, G P, Haas, K L, Schomer, L K, Heilbrun, B J, Cassin, J, Powell, J A, Montie, J E, Pontes, J D, Crissman   +9 more
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Multilocular prostatic cystadenoma with high-grade prostatic intraepithelial neoplasia

Urology, 2003
Multilocular prostatic cystadenoma is a rarely encountered neoplasm located in the midline between the bladder and rectum that is either attached to the prostate by a pedicle or separate from the prostate entirely. Histologically and immunohistochemically these lesions resemble benign prostate tissue.
Elizabeth A, Allen, David A, Brinker, Domenico, Coppola, Jose I, Diaz, Jonathan I, Epstein   +4 more
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Architectural patterns of high-grade prostatic intraepithelial neoplasia

Human Pathology, 1993
High-grade prostatic intraepithelial neoplasia (PIN) is characterized by cellular proliferations within pre-existing ducts and glands with cytologic changes mimicking adenocarcinoma, including prominent nucleoli, but lacking stromal invasion. To determine the architectural spectrum of high-grade PIN, 60 serially sectioned radical prostatectomy ...
D G, Bostwick, M B, Amin, P, Dundore, W, Marsh, D S, Schultz   +4 more
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Shifting Paradigms for High-grade Prostatic Intraepithelial Neoplasia

European Urology, 2016
High-grade prostatic intraepithelial neoplasia (HGPIN) has long been considered a histologic precursor to invasive prostate adenocarcinoma (PCA), with the canonical view stating that HGPIN progresses unidirectionally to PCA. This notion is based on the observations that HGPIN lesions are often found in close proximity to PCA and share a large ...
Michael C, Haffner, Christopher E, Barbieri   +1 more
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Significance of high-grade prostatic intraepithelial neoplasia on prostate biopsy

Urologic Oncology: Seminars and Original Investigations, 2003
The early diagnosis of prostate cancer has been facilitated by the development of serum prostate-specific antigen (PSA) testing and evolution in transrectal ultrasound-guided biopsy of the prostate. Over a decade has passed since the initial recommendations for systematic sextant sampling of the prostate to increase the accuracy of cancer detection ...
Maxwell V, Meng, Katsuto, Shinohara, Gary D, Grossfeld   +2 more
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Unusual Histologic Types of High-Grade Prostatic Intraepithelial Neoplasia

The American Journal of Surgical Pathology, 1997
High-grade prostatic intraepithelial neoplasia (HGPIN) is the most likely precursor proliferation of peripheral zone, moderately to poorly differentiated prostatic adenocarcinomas. The usual cell type of the epithelial lining of HGPIN is a glandular epithelial cell with characteristic nuclear abnormalities. Here we report nine cases of unusual types of
A O, Reyes, P E, Swanson, J M, Carbone, P A, Humphrey   +3 more
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