Results 251 to 260 of about 834,651 (394)

The Gut Commensal Butyricimonas Virosa Modulates Gut Microbiota‐Dependent Thiamine Metabolism and Attenuates Mouse Steatotic Liver Disease

Advanced Science, EarlyView.
This study reveals that dietary stachyose enriches Butyricimonas virosa, effectively attenuating metabolic dysfunction‐associated steatotic liver disease (MASLD). Mechanistically, B. virosa enhances gut thiamine monophosphate synthesis, which elevates hepatic thiamine pyrophosphate levels.
Ningning He, Haoyu Wang, Zizhen Yang, Hui Li, Bei Liu, Kaiwei Chen, Zhinan Wu, Xinnan Zhao, Hewei Liang, Mengmeng Wang, Xiaofang Li, Yiyi Zhong, Haifeng Zhang, Liang Xiao, Karsten Kristiansen, Jixing Peng, Yuanqiang Zou, Shangyong Li   +17 more
wiley   +1 more source

The Effects of Biofortified Cowpeas on Iron, Glucose, and Lipid Metabolism in Rats Fed a High-Fat/High-Sugar Diet. [PDF]

Mol Nutr Food Res
Gaspar APR, Sant' Ana CT, Grancieri M, Cruz APCM, Viana LS, Fornazier EL, Corrêa MDS, Venial HJ, Boeloni JN, Costa NMB.   +9 more
europepmc   +1 more source

LIVER FUNCTION AND LIPID METABOLISM MARKERS IN YOUNG ATHLETES FOLLOWING HIGH-PROTEIN DIETS

Kacper Trząsalski, Katarzyna Oświeczyńska, Aleksandra Sowa, Sebastian Kupisiak, Patrycja Jędrzejewska-Rzezak   +4 more
openalex   +2 more sources

Differential effects of dietary choline and methionine on plasma lipid levels in rats fed on a high cholesterol diet.

, 1991
Kimio SUGIYAMA, Akio Ohishi, Haruna Takano, Hisanao TAKEUCHI   +3 more
openalex   +2 more sources

Genome‐Wide CRISPR Screen Reveals PIK3CA Inhibition Enhances Lipid Nanoparticle‐Mediated siRNA Delivery

Advanced Science, EarlyView.
A genome‐wide CRISPR screen and identifies PIK3CA as a key regulator of lipid nanoparticle (LNP) uptake is performed. Modulating PIK3CA with small‐molecule inhibitor BAY1082439 enhanced LNP uptake, siRNA delivery, and gene silencing in a variety of epithelial cells, and improved therapeutic outcomes in vivo.
Wenhan Wang, Kangfu Chen, Zongjie Wang
wiley   +1 more source

Biochemical hepatic alterations and body lipid composition in the herbivorous grass carp (Ctenopharyngodon idella) fed high-fat diets

British Journal of Nutrition, 2006
Z. Du, P. Clouet, Wen-Hui Zheng, P. Degrace, L. Tian, Yong‐jian Liu   +5 more
semanticscholar   +1 more source

A Simplified Three‐Tailed N‐Alkyl Phosphoramidate Lipid Platform Enables Inguinal Adipose‐Accumulated mRNA Delivery for Anti‐Obesity Therapy

Advanced Science, EarlyView.
This study develops an mRNA therapy encoding a long‐acting GLP‐1/FGF21 fusion protein. A three‐tailed ionizable lipid engineered three‐component lipid nanoparticle delivers the mRNA to inguinal adipose tissue. In obese mice, this targeted, dual‐hormone treatment potently reduces body weight, fat mass, presenting a localized strategy for metabolic ...
Bin Ma, Yunxuan Liu, Huijuan Zhang, Yian Fang, Yizhe Xue, Junsheng Xue, Ziqiong Jiang, Tianyan Zhou, Yanyun Hao, Fei Xie, Lei Miao   +10 more
wiley   +1 more source

Impact of partial replacement of fish meal with polychaete meal (Hediste diversicolor) on growth, nutrient digestibility, fatty acid profiles, and fish-in: fish-out ratio in diets of European seabass, Dicenctrarchus labrax. [PDF]

Fish Physiol Biochem
Akbaş Y, Gümüş E, Koçer MAT, Kurtoğlu A, Aydın İ, Aktaş Ö, Pak F, Sevgili H.   +7 more
europepmc   +1 more source

Lipid-lowering activity of Cow urine ark in guinea pigs fed with a high cholesterol diet.

, 2014
Chawda Hiren Manubhai, Mandavia Divyesh Rasiklal, Baxi Seema Natvarlal, Vadgama Vishalkumar Kishorbhai, Tripathi Chandrabhanu Rajkishor   +4 more
openalex   +1 more source

Mechanisms of Aristolochic Acid Resistance in Specialist Butterflies and Evolutionary Insights for Potential Protective Pathways

Advanced Science, EarlyView.
The study provides an extreme example of insect adaptation to highly toxic defenses of host plants, and investigates the complex strategies to resist carcinogenic aristolochic acids, including physical isolation, metabolic detoxification, and DNA repair.
Yang Luan, Yubo Zhang, Jingjing Li, Jianqing Zhu, Yuyang Lei, Yushi Hu, Zhenqiang Xin, Tianpei Xie, Jiang Zheng, Yuanyuan Lin, Jingjing Shen, Yiyi Cao, Xinyue You, Jing Xi, Jiaying Wu, Weiying Liu, Xinyu Zhang, Yuanting Zheng, David J. Lohman, Leming Shi, Wei Zhang   +20 more
wiley   +1 more source