Advanced Science, EarlyView.Progressive stiffening of the hepatic extracellular matrix and free fatty acid overload activate the mechanosensor Piezo1 in steatotic hepatocytes, inducing calcium influx and nuclear translocation of Yes‐associated protein. YAP‐dependent nuclear signaling further drives inflammatory and fibrotic gene programs, lipid metabolic reprogramming, and ...
Juan Ma +15 more
wiley +1 more source
Simvastatin Improves the High-Fat-Diet-Induced Metabolic Disorder in Juvenile Chinese Giant Salamander (<i>Andrias davidianus</i>) Through Inhibiting Endoplasmic Reticulum Stress and Enhancing Mitochondrial Function. [PDF]
Animals (Basel)Wang Y +7 more
europepmc +1 more source
Stimulation of trace element absorption by major metals in vitro. [PDF]
, 1992 Adekalu, J. B., Heaton, F. W.
core +1 more source
Nanozymes Integrated Biochips Toward Smart Detection System
Advanced Science, EarlyView.This review systematically outlines the integration of nanozymes, biochips, and artificial intelligence (AI) for intelligent biosensing. It details how their convergence enhances signal amplification, enables portable detection, and improves data interpretation.
Dongyu Chen +10 more
wiley +1 more source
High Dietary Plant Protein Impairs Astaxanthin Pigmentation in Rainbow Trout by Disrupting Cholesterol-Bile Acid Metabolism and Gut Microbiota. [PDF]
Int J Mol SciVillasante A +10 more
europepmc +1 more source
Advanced Science, EarlyView.We generated multi‐tissue single‐cell transcriptomic atlases of camels and cattle, uncovering conserved and lineage‐specific cellular features across digestive and metabolic systems. Cross‐species comparisons revealed the evolutionary origin of the camel glandular sac and identified novel cell populations linked to physiological specialization ...
Tao Shi +22 more
wiley +1 more source
Ketogenic diets and metabolic dysfunction-associated steatotic liver disease: a literature review. [PDF]
Cell BiosciSun K +5 more
europepmc +1 more source
Resilient Calvarial Bone Marrow Supports Retinal Repair in Type 2 Diabetes
Advanced Science, EarlyView.Skull bone (calvarium) marrow in diabetic mice stay structurally intact and keeps making blood cells, unlike the bone marrow of the leg bones. The skull marrow is exposed to cerebrospinal fluid (CSF), which contains protective molecules called oxysterols.
Bright Asare‐Bediako +16 more
wiley +1 more source
Weight-loss effects of macronutrient-based diets modified by genetic variants: a protocol for systematic review of randomised controlled trials. [PDF]
BMJ OpenSubardjo YP +4 more
europepmc +1 more source
Polysaccharides from the Cherry Peel of Coffea arabica L. Attenuate Obesity by Altering Lipid Metabolism and Inflammation and Regulating Gut Microbiota in Mice Fed a High-Fat Diet [PDF]
Guiqin Hu +7 more
openalex +1 more source