Results 71 to 80 of about 834,651 (394)

Macrophage-derived upd3 Cytokine causes impaired glucose homeostasis and reduced lifespan in drosophila fed a lipid-rich diet [PDF]

, 2014
Long-term consumption of fatty foods is associated with obesity, macrophage activation and inflammation, metabolic imbalance, and a reduced lifespan. We took advantage of Drosophila genetics to investigate the role of macrophages and the pathway(s) that ...
Dionne, MS, Geissmann, F, Kierdorf, K, Pouchelon, CA, Vivancos, V, Woodcock, KJ   +5 more
core   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Adiponectin and adiponectin receptors in common carp (Cyprinus carpio): Tissue distribution and their expressions in response to high-carbohydrate and high-lipid diets

Aquaculture Reports, 2022
In order to investigate the roles of adiponectin in glucose and lipid metabolism in common carp, the tissue distribution of adiponectin and its receptor genes in common carp were firstly detected in this study, and then the effects of high-carbohydrate ...
Daming Pi, Junli Wang, Mengjuan Zhao, Mingyu Liu, Yingxin Zhang, Chaobin Qin, Liping Yang, Xiao Yan, Guoxing Nie   +8 more
doaj   +1 more source

Diet contributes to urban-induced alterations in gut microbiota : experimental evidence from a wild passerine [PDF]

, 2020
Urban sprawl increasingly affects the ecology of natural populations, including host-microbiota interactions, with observed differences in the gut microbiota between urban and rural hosts.
De Neve, Liesbeth, Lens, Luc, Matthysen, Erik, Salleh Hudin, Noraine, Teyssier, Aimeric, White, Joël   +5 more
core   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

A field study to optimize protein and lipid levels in diet for cage-cultured subadult rockfish Sebastes schlegelii

Aquaculture Reports
A feeding trial was conducted to evaluate growth, body composition, serum biochemistry, digestion and metabolism, and oxidation resistence of S. schlegelii fed 9 diets in a 3×3 factorial design (protein levels: 44 %, 48 %, 52 %; lipid levels: 6 %, 10 ...
Zhidong Song, Yuhua Liu, Peiyu Li, Baoshan Li, Tiantian Hao, Xiaoyan Wang, Chengqiang Wang, Lu Li   +7 more
doaj   +1 more source

Differential expression of lipid metabolism‐related genes and miRNAs in Ctenopharyngodon idella liver in relation to fatty liver induced by high non‐protein energy diets

, 2017
To explore the mechanism of fatty liver formation induced by high non-protein energy diets in grass carp (Ctenopharyngodon idella), basal diet and high-energy diets were fed to juvenile grass carp for 9 weeks.
Junli Wang, Ronghua Lu, Jun-jun Sun, Dizhi Xie, Feng Yang, G. Nie   +5 more
semanticscholar   +1 more source

Effect of high and low glycaemic index recovery diets on intramuscular lipid oxidation during aerobic exercise [PDF]

, 2008
Intramyocellular lipid (IMCL) and plasma NEFA are important skeletal muscle fuel sources. By raising blood insulin concentrations, carbohydrate ingestion inhibits lypolysis and reduces circulating NEFA.
Emma Stevenson, Jennie Brand-Miller, Karola Stockmann, Michael I. Trenell, Stannard, Stevenson   +5 more
core   +1 more source

Redox regulation meets metabolism: targeting PRDX2 to prevent hepatocellular carcinoma

Molecular Oncology, EarlyView.
PRDX2 acts as a central redox hub linking metabolic dysfunction‐associated steatohepatitis (MASH) to hepatocellular carcinoma (HCC). In normal hepatocytes, PRDX2 maintains redox balance and metabolic homeostasis under oxidative stress. In contrast, during malignant transformation, PRDX2 promotes oncogenic signaling, stemness, and tumor initiation ...
Naroa Goikoetxea‐Usandizaga, María Luz Martinez‐Chantar, Carolina Conter   +2 more
wiley   +1 more source

Effects of dietary lipid levels on growth performance and feed utilization in juvenile Black Sea turbot (Psetta maxima) with reference to nitrogen excretion

Marine Science and Technology Bulletin, 2014
In the present study, iso-nitrogenous test diets were formulated to contain two different levels of lipid (9% and 12%) with dietary energy ranging from 19 kJ/g to 20 kJ/g diet. White fish meal was the main protein source of the diet and the protein level
Fatma Burcu Harmantepe, Murat Yigit, Gaye Dogan, Zafer Karsli, Umut Yigit, Orhan Uyan   +5 more
doaj