Results 71 to 80 of about 1,467,276 (295)

Group-Fusion One-Dimensional Convolutional Neural Network for Ballistic Target High-Resolution Range Profile Recognition with Layer-Wise Auxiliary Classifiers

International Journal of Computational Intelligence Systems, 2023
Ballistic missile defense systems require accurate target recognition technology. Effective feature extraction is crucial for this purpose. The deep convolutional neural network (CNN) has proven to be an effective method for recognizing high-resolution ...
Qian Xiang, Xiaodan Wang, Jie Lai, Yafei Song, Rui Li, Lei Lei   +5 more
doaj   +1 more source

An attractor for the dynamical state of the intracluster medium

, 2012
Galaxy clusters provide us with important information about the cosmology of our universe. Observations of the X-ray radiation or of the SZ effect allow us to measure the density and temperature of the hot intergalactic medium between the galaxies in a ...
Barber, Binney, Buote, Cavaliere, Frederiksen, Hansen, Hansen, Host, Host, Kennicutt, Kneib, Li, Lynden-Bell, Sparre, Vikhlinin, Vikhlinin, ZuHone   +16 more
core   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Few-shot Radar High-resolution Range Profile: Target Recognition with Simulated Data Assistance

Leida xuebao
Research on target recognition using radar High-Resolution Range Profiles (HRRPs) is extensive and diverse in methodology. In particular, the application and development of deep learning to radar HRRP target recognition have enabled efficient, precise ...
Jian CHEN, Gang YU, Lan DU, Wenqiang DONG, Yuchen GUO   +4 more
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

The rationale and suggested approaches for research geosynchronous satellite measurements for severe storm and mesoscale investigations [PDF]

The measurements from current and planned geosynchronous satellites provide quantitative estimates of temperature and moisture profiles, surface temperature, wind, cloud properties, and precipitation.
Adler, R. F., Chesters, D., Shenk, W. E., Susskind, J., Uccellini, L.   +4 more
core   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

Radar HRRP Target Recognition Based on Deep One-Dimensional Residual-Inception Network

IEEE Access, 2019
A novel radar target recognition method based on the deep one-dimensional residual-inception network is proposed for a high-resolution range profile (HRRP).
Chen Guo, You He, Haipeng Wang, Tao Jian, Shun Sun   +4 more
doaj   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source