Results 61 to 70 of about 2,091,851 (310)

Interactions of Astrophysical Neutrinos with Dark Matter: A model building perspective

open access: yes, 2019
We explore the possibility that high energy astrophysical neutrinos can interact with the dark matter on their way to Earth. Keeping in mind that new physics might leave its signature at such energies, we have considered all possible topologies for ...
Karmakar, Siddhartha   +2 more
core   +1 more source

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

open access: yesFEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López   +2 more
wiley   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

The Green Future Building Through Energy Optimization in High‐Rise Buildings

open access: yesEnergy Science & Engineering
This study investigates the application of photovoltaic (PV) systems in 30‐meter high‐rise residential buildings in Tehran, evaluating the impact of four geographical orientations (north, south, east, and west).
Mobina Kalantari   +3 more
doaj   +1 more source

Cost overruns analysis in high rise building and apartment projects

open access: yesTạp chí Khoa học Đại học Mở Thành phố Hồ Chí Minh - Kinh tế và Quản trị kinh doanh, 2021
Cost overruns is the lasting problem in construction industry, appears in all over the world. This research was conducted to assess the influence of each factor to the cost overruns in construction projects. The percentage of cost overruns caused by each
Nguyễn Lê Kế Nghiệp   +2 more
doaj  

Livingstone versus Serota: the High-rise Battle of Bankside [PDF]

open access: yes, 2008
In 2001, plans were unveiled by a private developer for a 32-storey residential tower next to the Tate Gallery of Modern Art in Bankside. Although not the tallest building proposed within London's high-rise landscape, this tower became a minor cause ...
Harris, A.
core  

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

Numerical Simulation of Airflow around a High-Rise Building [PDF]

open access: yesE3S Web of Conferences
Details of the wind environment around high-rise buildings and the wind load acting on them vary with complex factors such as the shape and height of buildings.
Du Rongqiang
doaj   +1 more source

Asymptotically safe cosmology - a status report [PDF]

open access: yes, 2017
Asymptotic Safety, based on a non-Gaussian fixed point of the gravitational renormalization group flow, provides an elegant mechanism for completing the gravitational force at sub-Planckian scales. At high energies the fixed point controls the scaling of
Bonanno, Alfio, Saueressig, Frank
core   +4 more sources

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

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