Results 111 to 120 of about 36,236,534 (364)
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
An adaptive excitation source for high speed multiphoton microscopy
Nature Methods, 2019 Optical imaging is important for understanding brain function. However, established methods with high spatiotemporal resolution are limited by the potential for laser damage to living tissues.
Bo Li +4 more
semanticscholar +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Railway Engineering ScienceThe issue of fatigue damage to rails has become increasingly prominent with the rise in subway traffic and speed. The hazardous space of the turnout frog significantly intensifies the dynamic interaction between the vehicle and the frog rail, leading to ...
Zhaoguang Zheng +5 more
doaj +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
High speed miling in tool and die making
, 2022 S.263 ffThe development of superabrasive cutting materials and highspeed motor spindles has led to further development of High Speed Milling in tool and die making. The main focus is generally on engineering developments (machine, tools, etc.), while the
Klocke, Fritz, Altmüller, Stefan
core
China's High-speed Railway Industry and its Overseas Development [PDF]
, 2014 With 30 years of sustained economic growth, China is not only steadily pushing forward its domestic high-speed railway construction, but also positively articipating in the overseas railway market.
白, 春騮 +2 more
core +1 more source
Data processing and uncertainty evaluation method for five-hole probe considering compressibility [PDF]
AIP AdvancesThe data processing and uncertainty evaluation method of the five-hole probe, considering compressibility, is studied to meet the application requirements of the five-hole probe in a high-speed wind tunnel.
Yufeng Du +4 more
doaj +1 more source
FEBS Letters, EarlyView.Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas +3 more
wiley +1 more source
Calibration of Aluminum Sheets by High-Speed Hydroforming
A new, robust production system for tubular and sheet-based workpieces is presented. It combines the methodologies of high-speed forming with conventional hydroforming and is based on components and drive technology that can be easy controlled by the ...
Wieseler, T. +4 more
core +1 more source