Results 131 to 140 of about 41,974,173 (304)

Determination of GISSMO Damage Parameters for High-Speed Blanking of 22MnB5 and EN AW-5754 [PDF]

High-speed blanking (HSB) of high-strength materials, such as the steel 22MnB5, is an established method that delivers high-quality cut surfaces. Due to high shear rates, this process is associated with the formation of adiabatic shear bands (ASB) in the
Linnemann, Maik, Galiev, Elmar, Galiev, E., Linnemann, M., Winter, S., Psyk, V., Dix, M., Dix, Martin, Winter, Sven, Psyk, Verena   +9 more
core   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Reynolds Number Effects on Transonic Aerodynamic Characteristics of the CHN-T1 Standard Model

Aerospace
Experimental data at flight-relevant Reynolds numbers remain scarce for publicly available transport aircraft standard models. This study analyses Reynolds number effects on the CHN-T1 large-aspect-ratio configuration using measurements from the ...
Dawei Liu, Xin Peng, Qiang Li, Yanru Chen, Jia Meng   +4 more
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Experimental study on the mechanical properties of fly ash stabilized bentonite via sodium hydroxide-geopolymerization process

Scientific Reports
Expansive clay is problematic for transportation infrastructures due to its vulnerability to water induced decrease in strength. Building on existing geopolymer stabilization techniques, this study focuses on optimizing the mix design for expansive soils
Tengshen Jing, Shengyang Yuan, Xianfeng Liu, Yulin Liu, Haibin Xu, Weixing Zhou, Gaofeng Pan, Guanlu Jiang   +7 more
doaj   +1 more source

Tri-state study of high speed rail service

This report, the Final Report for the Tri-State Study of High Speed Rail Service, describes the work carried out by TMS/Benesch in analyzing the potential for high speed rail in the Tri-State Corridor.
TMS/Benesch Tri-State High Speed Rail Consultants
core  

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Machine Learning for High-Speed Corner Detection

European Conference on Computer Vision, 2006
E. Rosten, T. Drummond
semanticscholar   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Simulation on Buffet Response and Mitigation of Variant-Tailed Aircraft in Maneuver State

Vibration
This study proposes a computational fluid dynamics and computational structure dynamics (CFD/CSD) coupled method for calculating the buffet response of a variant tail wing.
Dawei Liu, Peng Zhang, Binbin Lv, Hongtao Guo, Li Yu, Yanru Chen, Bo Lu   +6 more
doaj   +1 more source