Results 51 to 60 of about 740 (163)

Biotransformation of Ambrisentan by A. niger and P. mineoluteum Monitored by High Performance Liquid Chromatography and Ultra High Performance Liquid Chromatography/Quadrupole Time‐of‐Flight Mass Spectrometry

SEPARATION SCIENCE PLUS, Volume 8, Issue 6, June 2025.
ABSTRACT The focus of the present study was the monitoring of ambrisentan (AMB) in vitro biotransformation by two fungal cultures: Aspegillus niger ATCC 9029 and Penicillium mineoluteum URM 6889. This drug is a selective endothelin Type A, receptor antagonist, used for pulmonary arterial hypertension.
Rafaela Martins Sponchiado, Brendha Lang Camboim, Julia Medeiros Sorrentino, Leticia Cordenonsi, Alexsandro Dallegrave, Alexandre Meneghello Fuentefria, Martin Steppe, Cássia Virginia Garcia   +7 more
wiley   +1 more source

A green separation mode of synephrine from Citrus aurantium L. (Rutaceae) by nanofiltration technology

Food Science &Nutrition, Volume 7, Issue 12, Page 4014-4020, December 2019., 2019
Thermal breakage of alkaloids ingredients was a common problem to which attention should be paid in the application of fruit ingredient separation. In this study, the mathematical models were based on the operating pressure and initial concentration to predict the rejection of synephrine.
Cunyu Li, Yun Ma, Jiamei Gu, Xinglei Zhi, Hemin Li, Guoping Peng   +5 more
wiley   +1 more source

Separation and Purification of Fructo-Oligosaccharide by High-Speed Counter-Current Chromatography Coupled with Precolumn Derivatization

, 2018
High-speed counter-current chromatography (HSCCC) coupled with precolumn derivatization was developed for isolating and purifying fructo-oligosaccharides (FOSs).
Wenhua Ji, Yuanan Wei, Yanling Geng, Feng Jing, Ruixuan Zhao, Xiao Wang, Wenjuan Duan, Zijian Chen   +7 more
core   +1 more source

Chemical Constituents of the Ethyl Acetate Extract from Diaphragma juglandis Fructus and Their Inhibitory Activity on Nitric Oxide Production In Vitro

Molecules, 2017
Diaphragma juglandis fructus contains various bioactive constituents. Fourteen compounds were isolated from Diaphragma juglandis fructus by preparative high performance liquid chromatography (pre-HPLC) and high-speed counter-current chromatography (HSCCC)
Dan Wang, Yan Mu, Hongjing Dong, Huijiao Yan, Cui Hao, Xiao Wang, Lisi Zhang   +6 more
doaj   +1 more source

Liquid Chromatographic and Capillary Electromigration Techniques for the Analysis of Azole Antifungals

Journal of Separation Science, Volume 48, Issue 4, April 2025.
ABSTRACT Since the introduction of azoles as antifungals in 1979, they gradually gained a spotlight in both medicinal and industrial fields. Other than being the leading antifungal medicinal drug agents, azoles have also been a major pesticide in agricultural industry.
Tuuliina Tuominen, Dumidu Perera, Giacomo Russo, Susanne K. Wiedmer   +3 more
wiley   +1 more source

Fingerprint Analysis of Cnidium monnieri (L.) Cusson by High-Speed Counter-Current Chromatography

, 2019
Cnidium monnieri (L.) Cusson is a popular Traditional Chinese Medicine (TCM) with a variety of bioactivities. However, there are some problems that have affected the development of Cnidium monnieri (L.) Cusson. At present, many methods have been reported
Xuemin Gao, Shuyi Zhang, Xuan Zhu, Xinmei Liu, Huayu Yang, Qing Chen, Xiaoxue Wu, Hua Song   +7 more
core   +1 more source

High speed counter current chromatography: A support-free LC technique

Journal of Pharmacy and Bioallied Sciences, 2009
As separation of components is the major requirement of an analytical chemist, there is always a need for a convenient high throughput technique with minimum sample loss, high efficiency, high resolution, and ease of sample recovery, without ...
Neha Sethi, Ankit Anand, Aarti Sharma, Kaushal K Chandrul, Garima Jain, Kona S Srinivasa   +5 more
doaj   +1 more source

Adsorption characteristics of modified bentonites for purification of anthocyanin from saffron tepal

Food Science &Nutrition, Volume 12, Issue 11, Page 9136-9150, November 2024.
The adsorption isotherms and kinetics of the anthocyanin on the modified bentonites extracted from waste of saffron flower was evaluated. The activation of bentonite by both acid and heat exhibited more adsorption than bentonite modified byonly acid or thermal.
Hasan Oliaei Torshizi, Samieh Oliaei
wiley   +1 more source

Preparative isolation and purification of phillyrin from the medicinal plant Forsythia suspensa by high-speed counter-current chromatography

, 2005
Forsythia suspensa (Thunb.) Vahl. has been used widely in traditional medicines to treat gonorrhea, erysipelas, inflammation, pyrexia and ulcer. It has also shown antioxidant activity, as well as antibacterial, antiviral, choleretic and antiemetic ...
Li, HB, Chen, F
core   +1 more source

Separation of Four Flavonoid Glycosides from Hydrocotyle sibthorpioides Lam. by High-speed Counter-current Chromatography

Shipin gongye ke-ji, 2022
For an improved study of flavonoid glycosides of great polarity from Hydrocotyle sibthorpioides Lam (HSL), the large polar flavonoid glycosides were extracted with n-BuOH, purified by DM 301 macroporous resin, Sephadex LH-20 and reversed-phase silica gel
Daoguang SONG, Zhi CHEN
doaj   +1 more source